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Search Results for: ross levine myeloma
Unraveling the use of CBD in veterinary medicine – Jill Lopez
Posted: Published on September 2nd, 2020
It was about the 3rd week into Bastions recovery from his TPLO surgery and he was already having a rough time. Continue reading
Posted in Spinal Cord Injury Treatment
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First gene therapy ‘a true living drug’ on the cusp of FDA … – Washington Post
Posted: Published on July 12th, 2017
PHILADELPHIA When doctors saw the report on Bill Ludwigs bone-marrow biopsy, they thought it was a mistake and ordered the test repeated. But the results came back the same: His lethal leukemia had been wiped out by an experimental treatment never before used in humans. We were hoping for a little improvement, remembered the 72-year-old retired New Jersey corrections officer, who had battled the disease for a decade. He and his oncologist both broke down when she delivered the good news in 2010. Nobody was hoping for zero cancer. The pioneering therapy administered to Ludwig and a few other adults at the University of Pennsylvania hospital paved the way for clinical trials with children. Six-year-old Emily Whitehead, who was near death, became the first pediatric recipient in 2012. Like Ludwig, she remains cancer-free. Such results are why the treatment is on track to become the first gene therapy approved by the Food and Drug Administration. An FDA advisory committee will decide Wednesday whether to recommend approval of the approach, which uses patients own genetically altered immune cells to fight blood cancers. If the panel gives the nod, the agency probably will follow suit by the end of September. That would … Continue reading
Posted in Cell Therapy
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Leukemia Patients' Outcomes Predicted With Genetic Profiling
Posted: Published on March 16th, 2012
Editor's Choice Academic Journal Main Category: Lymphoma / Leukemia / Myeloma Also Included In: Cancer / Oncology;Genetics Article Date: 16 Mar 2012 - 9:00 PDT email to a friend printer friendly opinions Current Article Ratings: Ross Levine, M.D., lead author of the study, member of Memorial Sloan-Kettering's Human Oncology Pathogenesis Program, and a medical oncologist on the Leukemia Service at Memorial Sloan-Kettering, said: We also want to use existing therapies more intelligently. It helps a great deal to know which subset of patients will actually benefit from intensive therapies, such as a higher dose of chemotherapy or a bone marrow transplant." Currently, there are just a few known genetic biomarkers that clinicians rely on in order to predict outcome in individuals suffering with leukemia. Although these biomarkers provide helpful information for some patients with AML, for the majority it is hard to predict the chance for a cure. The researchers used a method that incorporated information from a set of genes. This allowed them to categorize almost two-thirds of patients into clearly defined prognostic groups. Dr. Levine, explained: "Our goal was not to ask whether a certain gene or two raised or lowered risk, but to determine whether a combination … Continue reading
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The RARE List(TM) – You Must See it to Believe it!
Posted: Published on February 1st, 2012
To: HEALTH AND MEDICAL EDITORS 7,000 Different Rare Diseases and Disorders Comprise 65 Page RARE List(TM), 95% of the Medical Conditions Included on RARE List(TM) Have No FDA Approved Treatments DANA POINT, Calif., Feb. 1, 2012 /PRNewswire-USNewswire/ -- The R.A.R.E. Project (http://RAREproject.org), a leading patient advocacy organization representing the rare disease community, today issued the RARE List(TM), a stunning 65 page alphabetical listing of roughly 7,000 known rare diseases and disorders. The rare diseases and disorders that comprise the RARE List(TM) impact 30 million Americans (or 10% of the U.S. population) and an estimated 350 million people worldwide. The RARE List(TM) was released by the R.A.R.E. Project as part of month long public awareness campaign leading up to World Rare Disease Day on February 29, 2012. In 1983, the U.S. Orphan Drug Act legislation was passed in an attempt to encourage pharmaceutical companies to develop drugs for rare diseases that have a small market. However, during its first 25 years in existence, only 326 drugs were approved by the U.S. Food and Drug Administration (FDA) for all 7,000 rare disease and disorders on the RARE List(TM). Today, a shocking 95 percent of the medical conditions on the RARE List(TM) do … Continue reading
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