Monthly Archives: January 2012

Medical Treatments for Epilepsy – Video

Posted: Published on January 30th, 2012

08-12-2011 12:52 http://www.GeorgetownUniversityHospital.org Dr. Cesar C. Santos, pediatric neurologist at Georgetown University Hospital explains the medical treatments that are available for epilepsy. Read more from the original source: Medical Treatments for Epilepsy - Video … Continue reading

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Linda Foley, Executive Director, Families for Effective Autism Treatment – Video

Posted: Published on January 30th, 2012

24-01-2012 14:42 Comcast Newsmakers Western Washington is hosted by Sabrina Register. See the article here: Linda Foley, Executive Director, Families for Effective Autism Treatment - Video … Continue reading

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Redefining Autism: Will New DSM-5 Criteria for ASD Exclude Some People?

Posted: Published on January 30th, 2012

News | Mind & Brain Experts call for small and easy changes to the Diagnostic and Statistical Manual, the "bible" of psychiatry, so that everyone with autism spectrum disorder qualifies for a diagnosis By Ferris Jabr  | January 30, 2012 | DIAGNOSING THE DSM: The DSM-5 should sharpen the definition of autism, if the American Psychiatric Association makes a few tweaks in time Image: UrsaHoogle, iStockphoto People have been arguing about autism for a long time—about what causes it, how to treat it and whether it qualifies as a mental disorder. The controversial idea that childhood vaccines trigger autism also persists, despite the fact that study after study has failed to find any evidence of such a link. Now, psychiatrists and members of the autistic community are embroiled in a more legitimate kerfuffle that centers on the definition of autism and how clinicians diagnose the disorder. The debate is not pointless semantics. In many cases, the type and number of symptoms clinicians look for when diagnosing autism determines how easy or difficult it is for autistic people to access medical, social and educational services. The controversy remains front and center because the American Psychiatric Association (APA) has almost finished redefining autism, … Continue reading

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Rapid Round: What is a Stroke?

Posted: Published on January 30th, 2012

January 30, 2012 -- As Senator Mark Kirk continues to recover, we take a closer look at the warning signs of stroke. In Monday morning's Rapid Round, we're joined by Dr. Melvin Wichter, neurologist with Advocate Christ Hospital and Medical Center in Oak Lawn. 1) What are the signs you're having a stroke? No two strokes are alike, thus the expression "we learn strokes, stroke by stroke". However certain patterns are more common than others. The most important pattern is best remembered by the acronym F.A.S.T. Face meaning a drooped or twisted face, Arm weakness or drifting of the arm, Speech slurred speech or difficulty finding words, Time reminds us that "Time is Brain" and the shorter the time to appropriate therapy the less likely permanent damage will occur. 2) What Types of strokes are there? 85% of total strokes are due to blocked arteries which prevent blood from getting to particular parts of the brain. Overwhelmingly these kinds of stroke are related to the clotting of blood in the heart or the blockage of blood vessels in the neck or within the brain. These are often called "bland" or ischemic strokes they are directly or indirectly related to hardening … Continue reading

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Sen. Mark Kirk's Stroke Shows They Can Hit The Young, Too

Posted: Published on January 30th, 2012

WASHINGTON -- When a stroke hits at 52, like what happened to Sen. Mark Kirk of Illinois, the reaction is an astonished, "But he's so young." The reality is that strokes don't just happen to grandma. They can happen at any age, even to children – and they're on the rise among the young and middle-aged. That makes it crucial to know the warning signs no matter how old you are. "Nobody's invincible," warns Dr. Ralph Sacco, a University of Miami neurologist and past president of the American Heart Association. Every year, about 795,000 people in the U.S. have a stroke. While some strokes are caused by bleeding in the brain, most are like a clogged pipe. Called ischemic strokes, a clot blocks blood flow, starving brain cells to death unless that circulation is restored fast. Make no mistake, the vast majority of strokes do occur in older adults. But up to a quarter of them strike people younger than 65, Sacco says. In the so-called stroke belt in the Southeast, that figure can be markedly worse. At Wake Forest Baptist Medical Center in North Carolina, a stunning 45 percent of stroke patients are young or middle-aged, says stroke center … Continue reading

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Covidien device joins stroke treatment trial

Posted: Published on January 30th, 2012

The Solitaire FR Revascularization Device by Covidien plc won approval for investigational use in the thromectomy part of the Interventional Management of Stroke (IMS III) trial, funded by the National Institute of Neurological Disorders and Stroke. The IMS III Executive Committee approved the device’s inclusion in the trial and in an amendment made to the FDA. The Irish company, which has its U.S. headquarters in Mansfield, develops the Solitaire FR device, a device made to improve blood clots and restore blood flow. The IMS III trial is expected compare two ways to restore blood flow after stroke – the first way uses the current method of giving intravenous rTPA alone, as approved by the FDA, and the second uses a combined intravenous and intra-arterial treatment with the Covidien device. Covidien (NYSE: COV) announced last week that it had named Stacy Enxing Seng, a co-founder and former executive of ev3 Inc., as president of its Vascular Therapies Global Business Unit.  The company notably announced plans in December to spin off its pharmaceuticals business in order to focus entirely on its medical device and supply business.  The business, which is expected to become a stand-alone company, supplies branded generic pain killers, including … Continue reading

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Senator's stroke shows they can hit the young, too

Posted: Published on January 30th, 2012

WASHINGTON (AP) — When a stroke hits at 52, like what happened to Sen. Mark Kirk of Illinois, the reaction is an astonished, "But he's so young." The reality is that strokes don't just happen to grandma. They can happen at any age, even to children — and they're on the rise among the young and middle-aged. That makes it crucial to know the warning signs no matter how old you are. "Nobody's invincible," warns Dr. Ralph Sacco, a University of Miami neurologist and past president of the American Heart Association. Every year, about 795,000 people in the U.S. have a stroke. While some strokes are caused by bleeding in the brain, most are like a clogged pipe. Called ischemic strokes, a clot blocks blood flow, starving brain cells to death unless that circulation is restored fast. Make no mistake, the vast majority of strokes do occur in older adults. But up to a quarter of them strike people younger than 65, Sacco says. In the so-called stroke belt in the Southeast, that figure can be markedly worse. At Wake Forest Baptist Medical Center in North Carolina, a stunning 45 percent of stroke patients are young or middle-aged, says stroke … Continue reading

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Protect Your Brain…Why? – Video

Posted: Published on January 30th, 2012

20-11-2011 13:40 According to research published in Neurology®, the medical journal of the American Academy of Neurology, the development of aggressive behavior after brain injury is linked to injury location and gene expression. The article,Prefrontal cortex lesions and MAO-A modulate aggression in penetrating traumatic brain injury," is authored by a group headed by Jordan Grafman, PhD, director of traumatic brain injury research at Kessler Foundation. This is a follow-up study to the Vietnam Veterans Head Injury Project, which monitors long-term sequelae in more than 200 veterans with penetrating brain injury. Aggressive behavior develops in some individuals after traumatic brain injury--the signature wound of the wars in Iraq and Afghanistan. "Aggressive behavior not only hinders rehabilitation and recovery after brain injury, it's devastating to families. kesslerfoundation.org Head injury has become known as the "signature injury" of the Iraq war. The Website of the Defense and Veterans Brain Injury Center (DVBIC), a congressionally funded research and outreach agency, cites a brain injury rate of 62% among troops returning from combat duty in Iraq. Blast-related TBI, an effect of the over-pressurized shock wave that ripples out from an explosion, is a particular concern in the current conflicts. In the Walter Reed study, about … Continue reading

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Pfizer To Seek FDA Approval For Long-Stalled Menopause Drug

Posted: Published on January 30th, 2012

By Peter Loftus, Of DOW JONES NEWSWIRES Pfizer Inc. (PFE) is preparing to seek U.S. regulatory approval to sell a new menopause drug that could pose an alternative to the company's older hormone- replacement therapies, which have been tied to safety risks. However, repeated delays in developing the new drug, Aprela, have raised questions about its potential. Some analysts and doctors question whether regulators will approve it, and Aprela's market potential could be limited by continued safety concerns about hormone-based drugs. The New York-based drug maker expects to submit Aprela for U.S. Food and Drug Administration approval sometime this year, Olivier Brandicourt, president and general manager of Pfizer's primary care unit, said in an interview earlier this month. Brandicourt said Aprela has the potential to reduce menopausal symptoms including hot flashes and to prevent bone-thinning osteoporosis, but with a better safety and tolerability profile than older hormone-replacement therapies. "We think this is a market which is unsatisfied ... and if you can bring a hormone therapy which doesn't have the traditional side effects, we can actually lead that marketplace," Brandicourt told reporters at a November meeting. Many women stopped using hormone-replacement therapies after a large government study, the Women's Health … Continue reading

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Researchers turn skin cells into neural precusors, bypassing stem-cell stage

Posted: Published on January 30th, 2012

The multiple successes of the direct conversion method could refute the idea that pluripotency (a term that describes the ability of stem cells to become nearly any cell in the body) is necessary for a cell to transform from one cell type to another. Together, the results raise the possibility that embryonic stem cell research and another technique called "induced pluripotency" could be supplanted by a more direct way of generating specific types of cells for therapy or research. This new study, which will be published online Jan. 30 in the Proceedings of the National Academy of Sciences, is a substantial advance over the previous paper in that it transforms the skin cells into neural precursor cells, as opposed to neurons. While neural precursor cells can differentiate into neurons, they can also become the two other main cell types in the nervous system: astrocytes and oligodendrocytes. In addition to their greater versatility, the newly derived neural precursor cells offer another advantage over neurons because they can be cultivated to large numbers in the laboratory — a feature critical for their long-term usefulness in transplantation or drug screening. In the study, the switch from skin to neural precursor cells occurred with … Continue reading

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