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Archives
Monthly Archives: February 2012
Opexa Therapeutics Reports Year End 2011 Financial Results and Provides Corporate Update
Posted: Published on February 27th, 2012
THE WOODLANDS, Texas--(BUSINESS WIRE)-- Opexa Therapeutics, Inc. (NASDAQ:OPXA - News), a biotechnology company developing a novel T-cell therapy for multiple sclerosis (MS), today reported financial results for the year ended December 31, 2011 and provided an overview of corporate developments during the last year. 2011 highlights include: Clinical and Regulatory Granted Fast Track designation by the U.S. Food and Drug Administration (FDA) for Tovaxin® for the treatment of patients with Secondary Progressive Multiple Sclerosis (SPMS); Published the results of the Company’s prior Phase IIb TERMS clinical trial of Tovaxin in a leading peer-reviewed publication, Multiple Sclerosis Journal; Executed strategic agreements with the American Red Cross and the Blood Group Alliance, Inc. to streamline blood procurement for future clinical trials; and Met with Health Canada’s Biologics and Genetics Therapies Directorate as part of the process to secure approval for Opexa to conduct a portion of future clinical development in Canada. Operational Optimized the manufacturing process through the implementation of a functionally closed system and single cycle cGMP process; Advanced overall clinical plans for Tovaxin and clearly defined the study protocol for the planned Phase IIb clinical trial in SPMS; Increased employee headcount thereby strengthening our overall cell therapy expertise in preparation … Continue reading
Posted in MS Treatment
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Gilenya (Fingolimod): MS Drug Under Health Canada Review in Light of Serious Adverse Events
Posted: Published on February 27th, 2012
OTTAWA, ONTARIO--(Marketwire -02/27/12)- Health Canada is informing Canadians of an ongoing safety review of the multiple sclerosis (MS) drug Gilenya (the brand name for fingolimod). The review was initiated following reports of serious adverse events, including 11 deaths reported internationally. No deaths have been reported in Canada. Gilenya is a prescription drug authorized for the treatment of relapsing-remitting multiple sclerosis to reduce the frequency of attacks (relapses) and delay physical disability. Gilenya is generally recommended when other MS treatments have not been effective or cannot be tolerated. It was authorized in Canada in March 2011. Currently, it is not clear whether the deaths were caused by Gilenya or whether other factors may have played a role. Four of the 11 reports involved serious heart-related events (three involved heart attacks and one involved a disturbance of the heart rhythm), while the other seven are unexplained. Among these seven is a report involving a patient in the United States who died within 24 hours of taking the first dose. At the time of authorization, it was known that Gilenya can be associated with certain types of heart rhythm disturbances. The Canadian labelling contains several important warnings with respect to these risks. At … Continue reading
Posted in MS Treatment
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Hollywood Reaches Out to Help Westfall Foundation Fight Neuromuscular Disease
Posted: Published on February 27th, 2012
Writer/Actors Jayce and Tiffany Bartok are very familiar with the damaging effects of the neuromuscular disease “Friedreichs Ataxia.” Jayce wrote and starred in the award-winning movie, “The Cake Eaters,” starring Kristen Stewart, which features Stewart playing the role of “Georgia” who has the disease “Friedreichs Ataxia.” This grabbed Kerry Westfall's attention. Wildomar, CA (PRWEB) February 26, 2012 CEO of the Westfall Foundation, Kerry Westfall, was born with a neuromuscular disease called Friedreichs Ataxia. Friedreich's Ataxia (also called FA or FRDA) is a rare inherited disease that causes nervous system damage and movement problems. It usually begins in childhood and leads to impaired muscle coordination (ataxia) that worsens over time. Although there is no effective treatment or cure available, Friedreich's ataxia patients and families have more and more reason for real hope. In fact, that hope has been translated into increasing confidence that treatment and a cure for Friedreich's ataxia will be achieved. When Kerry watched “The Cake Eaters,” he vowed to meet and personally thank the writer, Jayce Bartok. Kerry obtained Jayces email address and told him about his video, “Commit to Your Health," he was inspired, and, although he was currently very busy producing his newest film, "Tiny Dancer,” … Continue reading
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Stem cell find offers hope for infertility
Posted: Published on February 27th, 2012
Stem cell find offers hope for infertility By Lauran Neergard Monday, February 27, 2012 An experiment that produced human eggs from stem cells could one day be a boon for women who are desperate to have a baby, according to a study published yesterday. The work sweeps away the belief that a woman has only a limited stock of eggs and replaces it with the theory that the supply is continuously replenished from precursor cells in the ovary, its authors said. If the report is confirmed, harnessing those stem cells might one day lead to better treatments for women left infertile because of disease — or simply because they’re getting older. "Our current views of ovarian aging are incomplete. There’s much more to the story than simply the trickling away of a fixed pool of eggs," said lead researcher Jonathan Tilly of Harvard’s Massachusetts General Hospital, who had long hunted these cells in a series of studies. His previous work drew fierce scepticism. Independent experts urged caution about the latest findings. A key next step is to see whether other laboratories can verify the work. If so, then it would take years of additional research to learn how to use … Continue reading
Posted in Stem Cell Research
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Seminar to focus on stem cell research development
Posted: Published on February 27th, 2012
The latest discoveries and promises of stem cell research and the development of new therapeutic approaches for a variety of diseases will be in focus at the Qatar International Conference on Stem Cell Science and Policy 2012 which begins today. The four-day event, being held at Qatar National Convention Centre, is a milestone in Qatar Foundation’s ongoing collaboration with the James A Baker III Institute for Public Policy at Rice University, Houston, Texas, US. The aim of QF’s joint initiative with the Baker Institute’s International Programme on Stem Cell Science Policy is to develop stem cell research in Qatar as well as to find ways to address the shared challenges of community support for stem cell research in Doha and Houston. To accomplish this goal, the programme has supported several events since its inception, including meetings, workshops, and training programmes in both cities. The conference, which brings together eminent international as well as regional scientists, ethicists and policymakers, will also present the developed policy options that account for cultural, ethical and religious factors. The event will draw attention to Qatar’s position in the development of stem cell research in the region and the world, given that research on stem cell … Continue reading
Posted in Stem Cell Research
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StemCells, Inc. to Participate in Qatar International Conference on Stem Cell Science and Policy 2012
Posted: Published on February 27th, 2012
NEWARK, Calif., Feb. 27, 2012 (GLOBE NEWSWIRE) -- StemCells, Inc. (Nasdaq:STEM - News) today announced that it will participate in the Qatar International Conference on Stem Cell Science and Policy, which is being held in Qatar from February 27 to March 1, 2012. The Company, which is the leader in development of cell-based therapeutics for central nervous system disorders, was specifically invited by the conference's sponsors, the State of Qatar and Amir of Qatar His Highness Sheikh Hamad bin Khalifa Al-Thani, as well as the James A. Baker III Institute for Public Policy of Rice University, and is the only company to be invited. Ann Tsukamoto, Ph.D., StemCells' Executive Vice President, Research and Development, will make a presentation on the clinical translation of human neural stem cells. StemCells was the first company to receive authorization from the US Food and Drug Administration to conduct a clinical trial of purified human neural stem cells, and the Company is currently conducting two clinical trials with a third anticipated to start later this year. Dr. Tsukamoto will also be the moderator of the panel session on neurological disorders, which is scheduled to be held on March 1 from 9:30 a.m. to 11:00 a.m. … Continue reading
Posted in Stem Cell Research
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Bad breath used as stem cell tool
Posted: Published on February 27th, 2012
27 February 2012 Last updated at 00:06 ET Hydrogen sulphide, the gas famed for generating the stench in stink bombs, flatulence and bad breath, has been harnessed by stem cell researchers in Japan. Their study, in the Journal of Breath Research, investigated using it to help convert stem cells from human teeth into liver cells. The scientists claimed the gas increased the purity of the stem cells. Small amounts of hydrogen sulphide are made by the body. It is also produced by bacteria and is toxic in large quantities. Therapy A group in China has already reported using the gas to enhance the survival of mesenchymal stem cells taken from the bone marrow of rats. Researchers at the Nippon Dental University were investigating stem cells from dental pulp - the bit in the middle of the tooth. They said using the gas increased the proportion of stem cells which were converted to liver cells when used alongside other chemicals. The idea is that liver cells produced from stem cells could be used to repair the organ if it was damaged. Dr Ken Yaegaki, from Nippon Dental University in Japan, said: "High purity means there are less 'wrong cells' that are … Continue reading
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Bad breath used as stem cell tool
Posted: Published on February 27th, 2012
27 February 2012 Last updated at 00:06 ET Hydrogen sulphide, the gas famed for generating the stench in stink bombs, flatulence and bad breath, has been harnessed by stem cell researchers in Japan. Their study, in the Journal of Breath Research, investigated using it to help convert stem cells from human teeth into liver cells. The scientists claimed the gas increased the purity of the stem cells. Small amounts of hydrogen sulphide are made by the body. It is also produced by bacteria and is toxic in large quantities. Therapy A group in China has already reported using the gas to enhance the survival of mesenchymal stem cells taken from the bone marrow of rats. Researchers at the Nippon Dental University were investigating stem cells from dental pulp - the bit in the middle of the tooth. They said using the gas increased the proportion of stem cells which were converted to liver cells when used alongside other chemicals. The idea is that liver cells produced from stem cells could be used to repair the organ if it was damaged. Dr Ken Yaegaki, from Nippon Dental University in Japan, said: "High purity means there are less 'wrong cells' that are … Continue reading
Posted in Mesenchymal Stem Cells
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Stem cell boost in fertility study
Posted: Published on February 27th, 2012
Researchers have isolated egg-producing stem cells from the ovaries of reproductive age women and shown these can produce what appear to be normal egg cells or oocytes, according to a new study. The discovery "opens the door for development of unprecedented technologies to overcome infertility in women" according to the scientist who led the study. Jonathan Tilly, of Massachusetts General Hospital in the United States, said: "The primary objective of the current study was to prove that oocyte-producing stem cells do in fact exist in the ovaries of women during reproductive life, which we feel this study demonstrates very clearly." The researchers developed a precise cell-sorting technique to isolate oocyte producing stem cells (OSCs) without contamination from other cells, according to an article in the March issue of Nature Medicine. The cells were able, in the laboratory, to form cells spontaneously with characteristic features of oocytes. Further experiments on mice showed such eggs could be fertilised. Dr Tilly's team is exploring potential clinical applications from its findings which include the establishment of human OSC banks - since these cells, unlike human oocytes, can be frozen and thawed without damage - and the development of mature human oocytes from OSCs for … Continue reading
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Seminar to focus on stem cell research development
Posted: Published on February 27th, 2012
The latest discoveries and promises of stem cell research and the development of new therapeutic approaches for a variety of diseases will be in focus at the Qatar International Conference on Stem Cell Science and Policy 2012 which begins today. The four-day event, being held at Qatar National Convention Centre, is a milestone in Qatar Foundation’s ongoing collaboration with the James A Baker III Institute for Public Policy at Rice University, Houston, Texas, US. The aim of QF’s joint initiative with the Baker Institute’s International Programme on Stem Cell Science Policy is to develop stem cell research in Qatar as well as to find ways to address the shared challenges of community support for stem cell research in Doha and Houston. To accomplish this goal, the programme has supported several events since its inception, including meetings, workshops, and training programmes in both cities. The conference, which brings together eminent international as well as regional scientists, ethicists and policymakers, will also present the developed policy options that account for cultural, ethical and religious factors. The event will draw attention to Qatar’s position in the development of stem cell research in the region and the world, given that research on stem cell … Continue reading
Posted in Cell Medicine
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