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Category Archives: MS Treatment

Treatment Options | MS Living Well

Posted: December 8, 2018 at 9:42 pm

AubagioAubagio (teriflunomide) is a once-a-day tablet for the treatment of adults with relapsing forms of multiple sclerosis (MS). The Aubagio 14 mg dose has been shown to reduce relapses by 31.5% in the TEMSO trial and 36% in the TOWER trial Continue reading

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Types of MS and MS Treatment Optionsmultiplesclerosis.com

Posted: at 9:42 pm

Patients usually experience a first neurologic event suggestive of MS known as Clinically Isolated Syndrome (CIS). It lasts for at least 24 hours, with symptoms and signs indicating either a single lesion (monofocal) or more than one lesion (multifocal) within the central nervous system.1 There are 4 types of MS Continue reading

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Pill for Relapsing MS | RRMS Treatment | GILENYA (fingolimod)

Posted: at 9:42 pm

GILENYA has a pregnancy registryclick here to learn more. *GILENYA can result in a slow heart rate when first taken. You will be observed by a health care professional for at least 6 hours after you take your first dose. Continue reading

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Comprehensive Care : National Multiple Sclerosis Society

Posted: December 5, 2018 at 10:42 am

Modifying the disease course More than a dozen disease-modifying medications have been approved by the U.S. Food and Drug Administration (FDA) to treat relapsing formsof MS Continue reading

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Multiple Sclerosis (MS) Symptoms and Treatment – OnHealth

Posted: November 29, 2018 at 6:48 pm

What Is MS? Multiple sclerosis (MS) is an autoimmune disease in which the body's immune system attacks its own central nervous system (the brain and spinal cord) Continue reading

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About Stem Cell Treatment for Multiple Sclerosis | StemGenex

Posted: November 1, 2018 at 9:53 am

UNDERSTANDING MULTIPLE SCLEROSIS Multiple sclerosis (MS) is an unpredictable, often disabling disease of the central nervous system (CNS) that disrupts the flow of information within the brain, and between the brain and body. According to the National Multiple Sclerosis Society, the disease is thought to affect more than 2.3 million people worldwide, that number may be a significant under estimate since MS is not a reportable disease and no centralized reporting system exists at this time. Also, MS can be difficult to diagnose. Since there is no single test for MS, the diagnosis can be missed, delayed or even incorrect. In MS, the immune system malfunctions destroying the myelin which is the fatty substance that coats and protects nerve fibers in the brain and spinal cord. Often times, the myelin is compared to the insulation coating that surrounds electrical wires. When the surrounding protective myelin is damaged and the nerve fibers are exposed, the messages traveling along the nerve become slow or potentially blocked. In some cases, the nerve becomes damaged. Adult stem cells are potentially the most diverse and effective healing agents ever known and have been proven to treat an astounding variety of conditions, ranging from injuries to … Continue reading

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Multiple sclerosis – Wikipedia

Posted: October 17, 2018 at 7:43 am

Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.[1] This damage disrupts the ability of parts of the nervous system to communicate, resulting in a range of signs and symptoms, including physical, mental, and sometimes psychiatric problems.[5][8][9] Specific symptoms can include double vision, blindness in one eye, muscle weakness, trouble with sensation, or trouble with coordination.[1] MS takes several forms, with new symptoms either occurring in isolated attacks (relapsing forms) or building up over time (progressive forms).[10] Between attacks, symptoms may disappear completely; however, permanent neurological problems often remain, especially as the disease advances.[10] While the cause is not clear, the underlying mechanism is thought to be either destruction by the immune system or failure of the myelin-producing cells.[3] Proposed causes for this include genetics and environmental factors such as being triggered by a viral infection.[8][11] MS is usually diagnosed based on the presenting signs and symptoms and the results of supporting medical tests.[4] There is no known cure for multiple sclerosis.[1] Treatments attempt to improve function after an attack and prevent new attacks.[8] Medications used to treat MS, while modestly effective, can have side effects … Continue reading

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Multiple Sclerosis Treatment & Management: Approach …

Posted: October 2, 2018 at 8:41 am

Disease-modifying therapies have shown beneficial effects in patients with relapsing MS, including reduced frequency and severity of clinical attacks. These agents appear to slow the progression of disability and the reduce accumulation of lesions within the brain and spinal cord. The disease-modifying agents for MS (DMAMS) currently approved for use by the US Food and Drug Administration (FDA) include the following: Interferon beta-1a (Avonex, Rebif) [6] Interferon beta-1b (Betaseron, Extavia) [7] Peginterferon beta-1a (Plegridy) [8] Glatiramer acetate (Copaxone) [9] Natalizumab (Tysabri) [10, 11] Fingolimod (Gilenya) [13] Teriflunomide (Aubagio) [14] Dimethyl fumarate (Tecfidera) [15, 16, 17, 18] Alemtuzumab (Lemtrada) [19, 20, 21] Daclizumab (Zinbryta) [22, 23] Fingolimod, teriflunomide, and dimethyl fumarate are administered orally; natalizumab and mitoxantrone are administered by intravenous infusion; interferon beta-1a (Avonex) is administered intramuscularly; and interferon beta-1a (Rebif), interferon beta-1b, and glatiramer acetate are administered by subcutaneous injection. Note that in January 2013, the FDA approved a single-use autoinjector (Rebidose, EMD Serono Inc./Pfizer Inc) for self-injection of interferon beta-1a (Rebif) in patients with relapsing forms of MS. [24] The ease of use, patient satisfaction and acceptability, and functional reliability of the Rebidose are supported by data from a 12-week open-label, single-group study in 109 patients. The autoinjector … Continue reading

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MS Relapse Rates: Measuring MS Treatment Efficacy in …

Posted: August 25, 2018 at 3:45 am

Measuring the effectiveness of treatments for multiple sclerosis (MS) is complicated; the disease biology is not entirely understood, and symptoms vary from person to person. While doctors and researchers continue to explore new endpoints for clinical trials that evaluate MS therapies, measuring relapse rates remains one of the most common. Neurologist Enrique Alvarez, M.D., Ph.D., at the University of Colorado, Denver, discusses the importance of continuing to evaluate potential new therapies based on their ability to reduce relapse rates, along with newer measures that are bolstering these evaluations. How do researchers measure the efficacy of new treatments for MS? NEUROLOGIST ENRIQUE ALVAREZ, M.D., PH.D., AT THE UNIVERSITY OF COLORADO, DENVER, EXPLAINS WHY RELAPSE RATES HAVE REMAINED A BENCHMARK IN MS TRIALS. Relapse rates are a benchmark for measuring the efficacy of new MS treatments in clinical trials. A relapse occurs when a new neurological symptom emerges or an old symptom gets worse for at least 24 hours. MS can cause a variety of symptoms such as vision loss, pain, fatigue or impaired coordination. Signs of a relapse can be reported by the patient, and may have an immediate impact on the quality of a patients life. Relapse rates also tend … Continue reading

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Vitamin D links to MS supported by study

Posted: July 26, 2018 at 10:11 am

SCIENTISTS have moved a step closer to understanding how to better treat multiple sclerosis (MS) after more evidence emerged of a crucial link to vitamin D. In the latest study, University of Tasmania researchers discovered that MS sufferers treated with interferon-beta, a common MS drug, had higher vitamin D levels than those not on the treatment. Interferon-beta caused patients to become far more efficient at making vitamin D in their skin, senior researcher Professor Bruce Taylor said. MS sufferers taking the drug had nearly three times as much vitamin D from the same amounts of sun exposure than those who didn't take interferon-beta, he said. The results also shed light on how the therapy works, which has previously been unclear although it was thought to effect the immune system. Interferon-beta only reduced the risk of having an MS attack if patients had sufficient levels of vitamin D in their system, Prof Taylor said. MS sufferers in Tasmania and other areas of low latitude, where it was impossible to absorb enough vitamin D from sunlight in winter, may need to consider vitamin D supplementation, he said. The study analysed around 200 people living with MS in southern Tasmanian between 2002 and … Continue reading

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