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Category Archives: Myocardial Infarction

Add-On Colchicine Cost-Effective After MI – MedPage Today

Posted: March 30, 2020 at 3:45 pm

Low-dose colchicine lowered the risk of ischemic cardiovascular (CV) events after MI, and did so cost-effectively, according to results from the Canadian COLCOT trial. The primary efficacy outcome -- CV death (CVD), MI, stroke, resuscitated cardiac arrest, or urgent hospitalization for unstable angina leading to revascularization -- occurred in 5.5% of the colchicine group versus 7.1% of the placebo group (HR 0.77, 95% CI 0.61-0.96, P=0.02), reported Michelle Samuel, PhD, of the Montreal Heart Institute, at the virtual American College of Cardiology (ACC) meeting Continue reading

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Aspirin Versus Clopidogrel Monotherapy for the Secondary Prevention of Recurrent Cerebrovascular Attack Following Previous Ischemic Stroke in Patients…

Posted: at 3:45 pm

Type 2 diabetes mellitus (T2DM) and stroke are two different diseases, but have many aspects in common. Aspirin is recommended as an initial treatment for the secondary prevention of recurrent ischemic stroke in patients with T2DM. However, clopidogrel is an oral antiplatelet drug that might be another choice in case of aspirin intolerance. Continue reading

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Safe to Skip Post-TAVR Clopidogrel in Patients on OAC for AF – Medscape

Posted: at 3:45 pm

The guidelines allow for the addition of short-term clopidogrel to an oral anticoagulant (OAC) in patients with an established OAC indication, such as atrial fibrillation (AF), who undergo transcatheter aortic valve replacement (TAVR). But does the extra antithrombotic protection come with safety issues? Continue reading

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Anatomic Burden, Ischemia Severity, and Outcomes in ISCHEMIA – TCTMD

Posted: at 3:45 pm

Anatomic severity of diseasebut not severity of ischemiapredicted the risk of death or MI over 4 years of follow-up in the ISCHEMIA trial, a new analysis shows. However, an invasive strategy as compared with medical therapy offered no benefit regardless of disease severity based on level of ischemia or extent of coronary disease, according to ISCHEMIA investigators. Continue reading

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Clopidogrel exposure along with aspirin and rivaroxaban should be minimised or avoided to reduce bleeding risk – Vascular News

Posted: at 3:45 pm

William R Hiatt More bleeding with background clopidogrel, even if not severe by adjudication, may be associated with broad consequences, including discontinuation of therapies. In the absence of clear benefit, clopidogrel exposure along with aspirin and rivaroxaban should be minimised or avoided to reduce this risk, concluded William R Hiatt (University of Colorado Anschutz School of Medicine, Aurora, USA), presenting a subgroup analysis of the VOYAGER-PAD trial during the American College of Cardiology/World Congress of Cardiologys virtual scientific sessions (ACC.20/WCC Virtual)originally scheduled to take place on 2830 March in Chicago, USA Continue reading

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The ACC.20/WCC Sessions Are Virtually Here: A Preview – Medscape

Posted: at 3:45 pm

CYBERSPACE Online learning rises to the next level starting March 28 with the ambitious, pioneering response from the American College of Cardiology (ACC) to the cancellation of its annual scientific sessions live meeting forced by the COVID-19 pandemic, uncharted territory in most every way. The sessions are going online in three simultaneous real-time streams and videos and slides on demand, archived for 30-day access. And it will be free to literally anyone with internet and a computer, tablet, or smartphone Continue reading

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Efficacy and Safety of High-intensity Statins in Patients With Acute Myocardial Infarction: An Asian Perspective – DocWire News

Posted: March 27, 2020 at 11:44 pm

BACKGROUND: The 2013 American College of Cardiology/American Heart Association cholesterol guideline recommends high-intensity statin (HIS) in patients with atherosclerotic cardiovascular disease, but little is known about the efficacy and safety of HIS in Asian ethnicity. We assessed the effects of HIS in Taiwanese with acutemyocardial infarction(AMI). Consecutive patients admitted for new AMI between January 2010 and December 2013 without prior statin use were enrolled from the Taiwan National Health Insurance Research Database Continue reading

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Cardiology in the Time of COVID-19 – Medscape

Posted: at 11:44 pm

Jaya Mallidi, MD, MHS We are in the midst of a pandemic. Continue reading

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Guidance on Cardiac Implications of COVID-19 (ACC, 2020) – Medscape

Posted: at 11:44 pm

In February 2020, the American College of Cardiology (ACC) released a clinical bulletin to address early cardiac implications of the current novel coronavirus epidemic, COVID-19 (coronavirus disease 2019).[1,2] The guidance is based on case reports as well as provides information on the potential cardiac implications from analog viral respiratory pandemics and offers early clinical guidance given current COVID-19 uncertainty." Because viral infections such as influenza can destabilize and worsen cardiac conditions, it is likely that COVID-19 will also have an effect, with varying severity in individuals, particularly given indications that 40% of patients with COVID-19 have underlying cardiovascular or cerebrovascular disease.[1,2] These patients are at high risk of having complications and/or dying. COVID-19-related cardiac complications include arrhythmia and acute cardiac injury Continue reading

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A Score to Differentiate Takotsubo Syndrome from Non-ST-Elevation Myocardial Infarction in Women at the Bedside – DocWire News

Posted: at 11:44 pm

OBJECTIVE: A score to distinguish Takotsubo syndrome (TS) from acute coronary syndrome would be useful to facilitate appropriate patient investigation and management. This study sought to derive and validate a simple score using demographic, clinical and ECG data to distinguish women with non-ST elevationmyocardial infarction(NSTEMI) from NSTE-TS Continue reading

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