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Category Archives: ALS Treatment

Vascular Biology 2019 – NAVBO

Posted: December 7, 2018 at 7:42 pm

October 27-31, 2019Asilomar Conference Grounds in Monterey, CAKeynote Lecture by Hal Dietz, Johns Hopkins Medical Center:Leveraging Natures Success: Lessons from Modifiers of Cardiovascular DiseaseWorkshops:Developmental Vascular Biology and Genetics Workshop VIII Organized by Victoria Bautch, University of North Carolina, Chapel Hill Co-organizer: Courtney Griffin, Oklahoma Medical Research Foundations Organized by Kayla Bayless, Texas A&M Health Science Center and Marlene Rabinovitch, Stanford University Co-organizers: Christopher Breuer, Nationwide Children's Hospital and Linda Demer, University of California, Los Angeles Microphysiological Models of the MicrocirculationIntegrative Function in the MicrocirculationOrganized by Walter Lee Murfee, University of Florida Earl P. Benditt Award LectureJudah Folkman Award in Vascular Biology LectureSpringer Junior Investigator Award LectureRecipients have not yet been determined Emerging Technologies and ImagingCo-sponsored by the Microcirculatory SocietyMary Dickinson, Baylor College of MedicineNew imaging modalities and vascular developmentRui Benedito, Centro Nacional de Investigaciones CardiovascularesUsing multispectral genetic mosaics to enlighten endothelial heterogeneity during angiogenesisNathan Lawson, University of MassachusettsGenetic dissection of vascular and lymphatic development in zebrafishTodd McDevitt, University of California, San FranciscoEngineering cardiac microtissues to interrogate mechanisms of heterotypic interactionsSong Hu, University of VirginiaListening with light: photoacoustic microscopy of the microcirculation in vivo Vascular Transcriptomics: Discovery and Therapeutic OpportunitiesOrganized by Jan Kitajewski, University of Illinois at Chicago Session Chairs: Jan Kitajewski, University of Illinois at Chicago and Nicholas Gale, RegeneronHenar Cuervo, University of Illinois at ChicagoTranscriptomic analysis of vascular pericytes and pericyte-associated diseaseChrister Betsholtz, Karolinska Institute/Uppsala UniversityVascular single-cell transcriptomicsAmber Stratman, Washington University in St Continue reading

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Lower vascular plant | botany |

Posted: at 7:42 pm

Alternative Titles:Pteridophyta, cryptogam, pteridophyte, seedless vascular plant, vascular cryptogam Lower vascular plant, formerly pteridophyte, also called vascular cryptogam, any of the spore-bearing vascular plants, including the ferns, club mosses, spike mosses, quillworts, horsetails, and whisk ferns. Once considered of the same evolutionary line, these plants were formerly placed in the single group Pteridophyta and were known as the ferns and fern allies Continue reading

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Myocardial infarction – Wikipedia

Posted: December 6, 2018 at 8:44 pm

Myocardial infarctionSynonymsAcute myocardial infarction (AMI), heart attackDiagram showing the blood supply to the heart by the two major blood vessels, the left and right coronary arteries (labelled LCA and RCA). A myocardial infarction (2) has occurred with blockage of a branch of the left coronary artery (1).SpecialtyCardiologySymptomsChest pain, shortness of breath, nausea, feeling faint, cold sweat, feeling tired[1]ComplicationsHeart failure, irregular heartbeat, cardiogenic shock, cardiac arrest[2][3]CausesUsually coronary artery disease[2]Risk factorsHigh blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol[4][5]Diagnostic methodElectrocardiograms (ECGs), blood tests, coronary angiography[6]TreatmentPercutaneous coronary intervention, thrombolysis[7]MedicationAspirin, nitroglycerin, heparin[7][8]PrognosisSTEMI 10% risk of death (developed world)[7]Frequency15.9 million (2015)[9] Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.[1] The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw.[1] Often it occurs in the center or left side of the chest and lasts for more than a few minutes.[1] The discomfort may occasionally feel like heartburn.[1] Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired.[1] About 30% of people have atypical symptoms.[7] Women more often present without chest pain and instead have neck pain, arm pain, or feel tired.[10] Among those over 75 years old, about 5% have had an MI with little or no history of symptoms.[11] An MI may cause heart failure, an irregular heartbeat, cardiogenic shock, or cardiac arrest.[2][3] Most MIs occur due to coronary artery disease.[2] Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others.[4][5] The complete blockage of a coronary artery caused by a rupture of an atherosclerotic plaque is usually the underlying mechanism of an MI.[2] MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others.[12][13] A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography.[6] An ECG, which is a recording of the heart's electrical activity, may confirm an ST elevation MI (STEMI) if ST elevation is present.[7][14] Commonly used blood tests include troponin and less often creatine kinase MB.[6] Treatment of an MI is time-critical.[15] Aspirin is an appropriate immediate treatment for a suspected MI.[8] Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes.[7][8] Supplemental oxygen is recommended in those with low oxygen levels or shortness of breath.[8] In a STEMI, treatments attempt to restore blood flow to the heart, and include percutaneous coronary intervention (PCI), where the arteries are pushed open and may be stented, or thrombolysis, where the blockage is removed using medications.[7] People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use of PCI in those at high risk.[8] In people with blockages of multiple coronary arteries and diabetes, coronary artery bypass surgery (CABG) may be recommended rather than angioplasty.[16] After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.[7] Worldwide, about 15.9 million myocardial infarctions occurred in 2015.[9] More than 3 million people had an ST elevation MI and more than 4 million had an NSTEMI.[17] STEMIs occur about twice as often in men as women.[18] About one million people have an MI each year in the United States.[2] In the developed world the risk of death in those who have had an STEMI is about 10%.[7] Rates of MI for a given age have decreased globally between 1990 and 2010.[19] In 2011, a MI was one of the top five most expensive conditions during inpatient hospitalizations in the US, with a cost of about $11.5 billion for 612,000 hospital stays.[20] Myocardial infarction (MI) refers to tissue death (infarction) of the heart muscle (myocardium). It is a type of acute coronary syndrome, which describes a sudden or short-term change in symptoms related to blood flow to the heart.[21] Unlike other causes of acute coronary syndromes, such as unstable angina, a myocardial infarction occurs when there is cell death, as measured by a blood test for biomarkers (the cardiac protein troponin or the cardiac enzyme CK-MB).[15] When there is evidence of an MI, it may be classified as an ST elevation myocardial infarction (STEMI) or Non-ST elevation myocardial infarction (NSTEMI) based on the results of an ECG.[22] The phrase "heart attack" is often used non-specifically to refer to a myocardial infarction and to sudden cardiac death. Continue reading

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Hyperbaric Medicine | University of Maryland Medical Center

Posted: December 5, 2018 at 10:41 am

Established in 1965, the Center for Hyperbaric Medicine at Shock Trauma is internationally recognized for its leadership and expertise in the clinical application of hyperbaric therapy. With the only multiplace hyperbaric chamber in the State of Maryland, the Center can accommodate up to 23 patients and care providers per dive. Conditions that are responsive to hyperbaric oxygen therapy include: Within this Center, recreational and commercial scuba divers can also undergo dive physicals to ensure they are healthy enough to dive. Continue reading

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Molecular Cardiology Research Institute Boston | Tufts …

Posted: November 29, 2018 at 6:45 pm

The Molecular Cardiology Research Institute (MCRI) at Tufts Medical Center in downtown Boston, MA studies the molecular mechanisms of common cardiovascular diseases including heart attack, stroke, heart failure, and high blood pressure then translates these discoveries into new clinical strategies for diagnosis and therapy. Our mission also emphasizes training and mentoring physicians and scientists committed to careers in cardiovascular research Continue reading

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What is an interventional cardiologist? | Heart Surgeries …

Posted: November 26, 2018 at 11:44 am

Interventional cardiologists rank among the world's foremost authorities on cardiovascular disease and its treatment. An interventional cardiologist is a cardiologist with additional education, training, certification, and experience in minimally invasive procedures performed on the heart and arteries. You might be referred to an interventional cardiologist for a test called an angiogram, which is used to diagnose blockages in your arteries. If tests reveal a problem, your cardiologist may recommend a procedure such as angioplasty or stenting. During angioplasty, the interventional cardiologist feeds a long, slender tube called a catheter into an artery. A balloon on the catheter opens at the site of the blockage, pushing a substance called plaque aside. Plaque builds up in arteries, eventually restricting blood flow. Angioplasty works to restore the flow of blood in the arteries. Sometimes the interventional cardiologist will also complete a stenting procedure, during which a tiny mesh tube called a stent is inserted into the artery at the angioplasty site to help keep the artery open. An interventional cardiologist is a critical part of the care team that will be with you throughout diagnosis, treatment, rehabilitation and prevention. Interventional cardiologists work closely with primary care physicians to coordinate patient cardiovascular care. Original … Continue reading

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Posted: November 24, 2018 at 7:42 pm

Inside NIMH Funding News for Current and Future NIMH Awardees. Find NIMH funding opportunities and announcements, including those specific to clinical research and training, and learn more about NIMH funding strategies, the application process, and grants management. Read More If you or someone you know has a mental illness, there are ways to get help. Use these resources to find help for yourself, a friend, or a family member. Read More Learn more about how to participate in outpatient and inpatient studies at the NIH Clinical Center, a hospital dedicated to the highest quality research. Read More Learn more about our research areas, policies, resources, and initiatives. Learn more about scientists, physicians, and clinicians in NIMHs Division of Intramural Research Programs (IRP). Learn more about Research Domain Criteria Initiative (RDoC), a research framework that supports new ways of studying mental disorders. Connect with Us on Twitter, Facebook, YouTube, and LinkedIn. Learn more about the NIH NeuroBioBank and brain tissue donation. Learn more about our research areas, policies, resources and initiatives. Learn more about scientists, physicians, and clinicians in NIMHs Division of Intramural Research Programs (IRP). Learn more about Research Domain Criteria Initiative (RDoC), a research framework that supports new ways … Continue reading

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Hyperbaric Oxygen Therapy for Wound Healing | Johns …

Posted: November 13, 2018 at 3:44 am

Hyperbaric oxygen therapy involves exposing the body to 100% oxygen at a pressure that is greater than what you normally experience. Wounds need oxygen to heal properly, and exposing a wound to 100% oxygen can, in some cases, speed the healing process. Hyperbaric oxygentherapy can be done in a number of ways. It can be given in a special type of room called a hyperbaric oxygen chamber.In this setting, you are completely immersed in 100% oxygen delivered at high pressure. It can also be given through a gas mask, which delivers 100% oxygen toyour lungs. The rest ofyour body is at normal oxygen levels, but still under higher pressure than normal. Hyperbaric oxygen therapy is used for certain types of wounds. Some of these are: Ask your provider if hyperbaric oxygen therapy is appropriate for your condition, particularly if you have diabetes-related wounds. Side effects of hyperbaric oxygen therapy are extremely rare but include: Pressure-related trauma toyour ears or nose Nearsightedness (This usually resolves within days to weeks after the last treatment.) Nonlife-threatening convulsions related to oxygen toxicity Decompression sickness A few patients with severe congestive heart failure have experienced additional problems with heart function after hyperbaric oxygen therapy.Share your … Continue reading

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Arrhythmia | Cleveland Clinic

Posted: November 2, 2018 at 5:41 am

What is an arrhythmia? An arrhythmia (also called dysrhythmia) is an irregular or abnormal heartbeat. Your pulse indicates your heart rate, or the number of times your heart beats in one minute. Pulse rates vary from person to person. Your pulse is slower when you are at rest and increases when you exercise, since more oxygen- rich blood is needed by the body during exercise. You can tell how fast your heart is beating by feeling your pulse. You can feel your pulse on your wrist or neck. Place the tips of your index and middle fingers on the inner wrist of your other arm, just below the base of your thumb. Or, place the tips of your index and middle fingers on your lower neck, on either side of your windpipe. Press lightly with your fingers until you feel the blood pulsing beneath your fingers. You may need to move your fingers around slightly up or down until you feel the pulsing. You can count the number of beats in 10 seconds and multiply by 6 to determine your heart rate in beats per minute. A normal heart rate, at rest, is 50 to 100 beats per minute. Your … Continue reading

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Cardiac Rhythm Disturbances | The Patient Guide to Heart …

Posted: at 5:41 am

Your doctor usually can diagnose a cardiac rhythm disturbance based on your symptoms, medical history, risk factors, a physical exam, and with results from tests and procedures. During a physical examination, your doctor will check your heart rate and rhythm, together with your pulse. If your doctor believes you may have a cardiac rhythm disturbance, he or she likely will order anelectrocardiogram(EKG) for confirmation. There also is a more advanced version of an EKG where your doctor may ask you to wear an event (or Holter) monitor. This is a portable device that is the size of a smartphone or smaller and can be worn under clothing, similar to an exercise heart rate monitor. This device will relay information back to your doctor and identify any abnormal rhythms that might happen intermittently, but not all of the time. The monitor usually is worn for 24-48 hours to get the required information. Your doctor also may recommend one or more of the following: echocardiogram (echo), chest x-ray, blood tests, stress test, and coronary angiography. For more information on these tests, visit our common diagnostic tests page. If your family doctor discovers the heart rhythm problem, you likely will be referred to … Continue reading

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