Category Archives: Cardiac Regeneration

Cardiac muscle – Wikipedia

Posted: April 24, 2018 at 1:41 am

Cardiac muscle (heart muscle) is one of the three major types of muscle, the others being skeletal and smooth muscle. It is an involuntary, striated muscle that is found in the walls of the heart. This muscle tissue is known as myocardium, and forms a thick middle layer between the outer layer of the heart wall (the epicardium) and the inner layer (the endocardium). Continue reading

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Myogenesis – Wikipedia

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Myogenesis is the formation of muscular tissue, particularly during embryonic development. Muscle fibers generally form the fusion of myoblasts into multi-nucleated fibers called myotubes. In the early development of an embryo, myoblasts can either proliferate, or differentiate into a myotube. Continue reading

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Zebrafish Heart Regeneration | HHMI BioInteractive

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More About Zebrafish Heart Regeneration When the zebrafish heart is damaged, the wound site is rapidly sealed with a fibrin clot that stems bleeding within seconds. Following clot formation, the tissue that surrounds the heart musclethe epicardiumgradually covers the fibrin clot via migration and cell division Continue reading

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Cardiac Regeneration – Mayo Clinic

Posted: April 22, 2018 at 5:40 am

Reparative stem cells have the capability to restore function to damaged tissue by renewing cell growth (shown in green) in cardiac cells destroyed by heart disease. Continue reading

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Cardiac Regeneration – What Science Can Do – AstraZeneca

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The partnership dates back to March 2013, when Moderna Therapeutics and AstraZeneca signed a five year exclusive option agreement to apply the companys platform in the search for new ways to treat cardiovascular and other diseases. In preparation for the first in-human safety studies the two companies are now working towards taking a mRNA therapeutic candidate through toxicology studies while addressing further in vivo proof of concept and targeted delivery. Ken and I speak several times a week to keep the programme moving and to discuss novel applications of this fascinating technology, says Dr Fritsche-Danielson. Continue reading

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Cardiac Regeneration – Center for Regenerative Medicine – Mayo Clinic …

Posted: April 11, 2018 at 9:40 am

Reparative stem cells have the capability to restore function to damaged tissue by renewing cell growth (shown in green) in cardiac cells destroyed by heart disease. Approximately 28 million Americans have been diagnosed with heart disease. Traditional medical therapies are not able to fully address the burden of disease, and the shortage of organs for transplantation remains a key barrier more than 117,000 people are on the national transplant list. Continue reading

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Cardiac Repair and Regeneration Research Unit | Heart and …

Posted: April 5, 2018 at 8:42 pm

DEB Laboratory Research Aims: We broadly investigate mechanisms of cardiac repair and regeneration and in particular study the interface of scar forming cells and cardiac progenitors in regulating a cardiac injury response. We use a variety of genetic, molecular and physiologic approaches to study how the outcome of a repair response can be manipulated to minimize scarring and enhance cardiac function. Continue reading

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