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Category Archives: Cardiac Regeneration

What the Hippo pathway in cardiac fibroblasts reveals about heart function – Baylor College of Medicine News

Posted: October 19, 2019 at 10:47 pm

Heart failure remains the leading cause of mortality in the U.S. During a heart attack, blood stops flowing into the heart. Without oxygen, part of the heart muscle dies Continue reading

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TAMassociati: the new Church of the Resurrection in Varignano – Floornature.com

Posted: October 14, 2019 at 1:43 am

The social and urban regeneration of a territory is only possible when ties are created or strengthened among its inhabitants. Translated into architecture, this means designing places for social interaction, where users can rediscover a sense of community. Continue reading

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Reviewing resTORbio Inc. (TORC)’s and Anika Therapeutics Inc. (NASDAQ:ANIK)’s results – MS Wkly

Posted: at 1:43 am

Since resTORbio Inc. (NASDAQ:TORC) and Anika Therapeutics Inc Continue reading

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Regenerative medicine today: Are diabetes and vascular disease treatments ready for the clinic? – Science Magazine

Posted: October 5, 2019 at 10:43 am

Regenerative medicinewhich involves regrowing damaged or dysfunctional cells, tissues, and organs, in order to treat and cure human diseaseholds great promise. Discoveries in stem cell research and tissue engineering as well as advances in regulatory and industry support have brought regenerative medicine treatments closer than ever to the clinic. Continue reading

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Tenaya Therapeutics Closes $92 Million Series B Financing – BioSpace

Posted: at 10:43 am

SOUTH SAN FRANCISCO, Calif., Oct. 3, 2019 /PRNewswire/ -- Tenaya Therapeutics, Inc., a company with a mission to discover, develop, and deliver curative therapies that target the underlying causes of heart disease, today announced the successful completion of a $92 million Series B financing Continue reading

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New insights into heart’s healing capacity – Baylor College of Medicine News

Posted: September 29, 2019 at 8:43 pm

A group of researchers at Baylor College of Medicine, the Texas Heart Institute and the University of Texas Health Science Center at Houston reveals today in the journal Genes & Development new insights into the recently discovered healing capacity of the heart involving the Hippo cellular pathway. The group previously reported that inactivating the Hippo pathway in the adult murine heart promoted cardiac muscle regeneration after injury, opening the possibility of developing promising heart failure therapies. In this study, the researchers discovered that inactivating the Hippo pathway in cardiac fibroblasts, non-muscle heart cells intertwined with cardiac muscle cells, promoted cardiac fibrosis and adversely effected cardiac function Continue reading

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The nanoengineer working to mend broken hearts – UNSW Newsroom

Posted: at 8:43 pm

When Hossein Tavassoli first told his mother that he was researching heart disease, she responded with But, youre an engineer... She was right, of course Hosseins undergraduate degree was in material engineering but at the time, he found it difficult to explain the intersections between biology and engineering. Now, not only is he a nanoengineer working in a tissue regeneration lab, but he is also an avid science communicator Continue reading

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Conjugated polymers optically regulate the fate of endothelial colony-forming cells – Science Advances

Posted: at 8:43 pm

Abstract The control of stem and progenitor cell fate is emerging as a compelling urgency for regenerative medicine. Here, we propose a innovative strategy to gain optical control of endothelial colony-forming cell fate, which represents the only known truly endothelial precursor showing robust in vitro proliferation and overwhelming vessel formation in vivo Continue reading

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New Insights Into the Healing Capacity of the Heart: The Hippo Pathway – Cath Lab Digest

Posted: September 26, 2019 at 10:46 am

HOUSTON, TX (Sept. 25, 2019)-A group of researchers atBaylor College of Medicine, theTexas Heart Instituteandthe University of Texas Health Science Center at Houstonreveals today in the journalGenes & Developmentnew insights into the recently discovered healing capacity of the heart involvingthe Hippo cellular pathway. Continue reading

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MTS Science

Posted: May 3, 2019 at 2:47 am

Ischemic heart disease remains the leading cause of mortality (12.7 %) worldwide, causing more than 7 million deaths per year.Native angiogenesis after infarction most often is not sufficient for appropriate supply of hibernating cardiomyocytes, leading to pathologic left ventricle (LV) remodeling and ischemic cardiomyopathy, a clinical entity characterized by a poor prognosis and severe symptoms in affected patients. Management of this disease often is limited, and curative strategies beside heart transplantation are lacking Continue reading

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