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Category Archives: Ventricular Remodeling

Causes and Prevention of Ventricular Remodeling After MI …

Posted: March 16, 2020 at 9:44 pm

Adverse ventricular remodeling after myocardial infarction (MI) is a process of regional and global structural and functional changes in the heart as a consequence of loss of viable myocardium, exuberant inflammatory response, increased wall stress in the border zone and remote myocardium, and neurohormonal activation (Figure 1). Continue reading

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FierceMedTech Names BioVentrix as One of Its "Fierce 15" Companies of 2019 – Yahoo Finance

Posted: March 15, 2020 at 7:44 pm

BioVentrix, Inc., developer of the first hybrid transcatheter device for left ventricular remodeling after a heart attack, today announced that it has been named by FierceMedTech as one of the "Fierce 15" for 2019, designating it as one of the most promising private medtech companies in the industry. The company offers Less Invasive Ventricular Enhancement, or the LIVE Therapy, which uses the Revivent TC Transcatheter Ventricular Enhancement System to exclude scar tissue on the left ventricle that has occurred from a heart attack so the healthy portion of the heart can operate more efficiently. Continue reading

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Relationship between histopathological features of aspirated thrombi and long-term left ventricular function in patients with ST-segment elevation…

Posted: at 7:44 pm

OBJECTIVE: This study was an investigation of the severity of inflammation (SOI) in aspirated material and thrombus age to examine any association with pre-discharge and long-term left ventricular (LV) function after ST-elevationmyocardial infarction(STEMI). The study group comprised 25 patients with STEMI from whom an occlusive thrombus was aspirated from the infarct-related artery with a 7-F catheter. The SOI in the aspirate was determined according to the mean leukocyte count in 5 high-power magnification fields and graded as mild in the presence of 100 leukocytes per field or significant if there were > 100 leukocytes per field Continue reading

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BioVentrix Announces Ralph Stephan von Bardeleben, MD, as Co- Principal Investigator of the REVIVE-HF Clinical Trial – Yahoo Finance

Posted: March 5, 2020 at 5:44 am

REVIVE-HF seeks to demonstrate superiority of the Revivent TC System to current guideline treatment for heart failure BioVentrix, Inc., developer of the first transcatheter device for left ventricular remodeling after a heart attack, today announced that Ralph Stephan von Bardeleben, MD, of the University Medical Center of Mainz (Germany) has joined the European REVIVE-HF clinical trial of the Revivent TC Transcatheter Ventricular Enhancement System as co-principal investigator. Continue reading

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New Data Confirms Cardiac Dimensions’ Carillon System Shows Favorable Long-Term Survival Rate In Patients With Functional Mitral Regurgitation -…

Posted: February 26, 2020 at 5:46 am

KIRKLAND, Wash., Feb. Continue reading

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Coronary Microvascular Dysfunction Found to Increase Risk for CV Events in Chronic Kidney Disease – The Cardiology Advisor

Posted: February 1, 2020 at 7:48 am

Coronary microvascular dysfunction was found to be associated with an increased risk for cardiovascular events and cardiac dysfunction in patients with chronic kidney disease, according to a study published in Circulation. In this longitudinal study, 352 patients without overt coronary, valvular, or end-organ disease, who underwent cardiac stress positron emission tomography (PET), echocardiogram, and renal function assessment at Brigham and Womens Hospital in Boston, Massachusetts, between 2006 and 2016 were enrolled Continue reading

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Retinoid X receptor alpha is a spatiotemporally predominant therapeutic target for anthracycline-induced cardiotoxicity – Science Advances

Posted: at 7:48 am

INTRODUCTION Anthracycline is a group of chemotherapeutic drugs that are being actively used to treat broad types of cancer (1, 2), but the major clinical complication for these antibiotics is their dose-dependent cardiotoxicity (1). Several mechanisms have been proposed for anthracycline-induced cardiotoxicity (AIC), including topoisomerase II (coded by TOP2B) as a primary mediator (3). On the basis of these mechanisms, dexrazoxane, an iron chelator, has been successfully developed as the only U.S Continue reading

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Increased Long-Term Risk for Venous Thromboembolism After Heart Failure – The Cardiology Advisor

Posted: January 23, 2020 at 7:46 pm

The long-term risk for a venous thromboembolism (VTE) event was found to be associated with the occurrence of heart failure with preserved or reduced ejection fraction, and with left ventricular remodeling, according to a study published in the Journal of the American College of Cardiology. In this prospective, population-based study, the short- and long-term risk for a VTE event was assessed in patients enrolled in the Atherosclerosis Risk in Communities study Continue reading

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Clinical Phenogroups in Heart Failure With Preserved Ejection Fraction: Detailed Phenotypes, Prognosis, and Response to Spironolactone – DocWire News

Posted: at 7:46 pm

Objectives This study sought to assess if clinical phenogroups differ in comprehensive biomarker profiles, cardiac and arterial structure/function, and responses to spironolactone therapy. Previous studies identified distinct subgroups (phenogroups) of patients with heart failure with preserved ejection fraction (HFpEF). Continue reading

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Early Expressed Circulating Long Noncoding RNA CHAST is Associated with Cardiac Contractile Function in Patients with Acute Myocardial Infarction -…

Posted: January 13, 2020 at 6:49 pm

BACKGROUND: The mortality rate during the acutemyocardial infarction(AMI) phase has substantially decreased, but post-AMI cardiac remodeling remains an important factor affecting patient prognosis. Continue reading

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