Monthly Archives: February 2012

Novelos Therapeutics Announces Enrollment of First Patient in Lung Cancer Trial With I-124-CLR1404 (Light) Cancer …

Posted: Published on February 22nd, 2012

MADISON, WI--(Marketwire -02/22/12)- Novelos Therapeutics, Inc. (OTCQX: NVLT.OB - News) a pharmaceutical company developing novel drugs for treatment and diagnosis of cancer, today announced that the University of Wisconsin Carbone Cancer Center, a leading medical oncology research institution, has enrolled the first patient in a Phase 1-2 positron emission tomography (PET) imaging trial of I-124-CLR1404 (LIGHT), a cancer-targeted PET imaging agent, in patients with advanced non-small cell lung cancer (NSCLC). Details of the trial design are available at http://www.clinicaltrials.gov ID: NCT00582283, or at http://www.novelos.com in the 'Clinical Trials' section. Anne M. Traynor, M.D., is the trial's principal investigator. "Surgical resection in properly selected NSCLC patients offers the best chance for long-term survival and may be curative. Consequently, accurate pre-operative assessment of local, regional and distant metastatic spread is critical for effective disease management," said Dr. Traynor. "If metastatic spread can be more accurately detected, we may be able to customize and optimize treatment decisions." "We are very pleased to be expanding our collaboration with the UW Carbone Cancer Center," said Harry Palmin, President and CEO of Novelos. "We look forward to obtaining initial LIGHT imaging data in the second quarter of 2012 in lung cancer patients. We believe positive data … Continue reading

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Editor’s move sparks backlash

Posted: Published on February 22nd, 2012

Bioethicist Glenn McGee’s new job raised questions of conflict of interest at the journal he founded. J. WILSON/KRT/NEWSCOM The field of bioethics is embroiled in a period of soul-searching, sparked by a startling career move by one of its biggest names. Glenn McGee is the editor-in-chief of the American Journal of Bioethics (AJOB), the most cited bioethics journal, which he founded in 1999. Since December 2011, he has also been president for ethics and strategic initiatives at CellTex Therapeutics in Houston, Texas, a controversial company involved in providing customers with unproven stem-cell therapies. A CellTex press release says that “Dr McGee’s responsibilities will include ensuring that all of the firm’s work, centered on adult stem cells, will meet the highest ethical standards of the medical and scientific communities.” Although McGee has said he will leave the journal on 1 March, many bioethicists have criticized him, the journal’s editorial board and its publisher, London-based Taylor and Francis. They argue that in holding both posts, McGee has a conflict of interest between his responsibilities to the journal and his new employer’s desire to promote the clinical application of stem-cell treatments that are not approved by the US Food and Drug Administration. “Imagine … Continue reading

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Bioethics Backlash

Posted: Published on February 22nd, 2012

Bioethicists debate how to remain impartial as a bioethics journal editor joins a company that peddles unproven stem cell therapies. By Sabrina Richards | February 22, 2012 Bioethicists are debating how, or even whether, one can remain impartial when working for industry as Glenn McGee, founder and editor of the American Journal of Bioethics, joins CellTex, a company that banks patients’ cells for untested stem cell therapies, reported Nature. McGee, who joined CellTex in December of last year and will step down from AJOB on March 1, says he hopes to bring ethical standards to CellTex’s stem cell trials. CellTex licenses therapies from RNL Bio, a South Korea-based company that converts patients’ fat cells into patient-specific mesenchymal stem cells, which the company claims can be reinjected to treat conditions like spinal cord injury. To date, no clinical trials have been completed that back these claims. Though criticism has been leveled at McGee for joining CellTex while remaining at AJOB, observers also wonder whether bioethicists can work in industry at all. McGee has argued that bioethicists have a place in industry, thereby helping bioethics to have a practical purpose. Others, such as Insoo Hyun, a stem-cell bioethicist at Case Western Reserve … Continue reading

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VistaGen Therapeutics Engages MissionIR as Its Investor Relations Advisor

Posted: Published on February 22nd, 2012

ATLANTA, GA--(Marketwire -02/21/12)- VistaGen Therapeutics, Inc. (OTC.BB: VSTA.OB - News) (OTCQB: VSTA.OB - News), a biotechnology company applying stem cell technology for drug rescue and cell therapy, has retained MissionIR, a national investor relations consulting firm, to develop and implement a strategic investor relations campaign. Through a network of investor-oriented online websites and full suite of investor awareness services, MissionIR broadens the influence of publicly traded companies and enhances their ability to attract growth capital and improve shareholder value. "VistaGen's work with human stem cell technology is groundbreaking," said Sherri Snyder, Director of Marketing at MissionIR. "The company's versatile platform, Human Clinical Trials in a Test Tube™, provides clinically relevant predictions of potential heart toxicity of new drug candidates long before they are ever tested on humans. Guided by a management team with decades of experience, VistaGen's stem cell technology can potentially save billions of dollars in the healthcare industry while recapturing prior R&D investment in once-promising new drug candidates." "We are pleased to bring MissionIR on board as our external investor relations partner," said Shawn Singh, VistaGen's Chief Executive Officer. "The crucial work our company is doing can fundamentally change the way medicine is developed. Paired with MissionIR's global … Continue reading

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Man 'stole dying son's care cash'

Posted: Published on February 22nd, 2012

21 February 2012 Last updated at 16:32 ET A businessman is accused of stealing £16,500 from a trust fund set up to pay for his son to have stem cell treatment in China for motor neurone disease. Cardiff Crown Court heard people raised £55,000 in sponsored runs after Julian Emms, 46, of Caerwent, Monmouthshire, established a charity for son Michael. A blank cheque he obtained to take him on a £3,000 trip to New York was cashed for the larger amount, the jury heard. Mr Emms denies fraud. The trial continues. The jury was told on Tuesday that Michael Emms was diagnosed with motor neurone disease, a degenerative neurological condition, while in his teens. Continue reading the main story Emms went to their home and burned the cheques in front of them in a way which was deliberately theatrical” End Quote Meirion Davies Prosecuting The fundraising allowed him to go abroad for stem cell treatment but this failed. After this, the jury was told, Mr Emms told his family he wanted £3,000 to fulfil Michael's dream of visiting New York. He approached Michael's grandmother, Anne Brandon, one of the four people authorised to sign the charity's cheques, the court heard. … Continue reading

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MediVet-America Partners With Butler Schein Animal Health to Distribute World's Leading Animal Stem Cell Technology to …

Posted: Published on February 22nd, 2012

Global leader in animal stem cell technology is poised for significant expansion through new partnership with top U.S. companion animal health distribution company. Las Vegas, Nevada (PRWEB) February 22, 2012 MediVet-America, the global leader in veterinary stem cell technology and regenerative medicine, has entered into a distribution partnership with Butler Schein Animal Health, a division of Henry Schein, the leading companion animal health distribution company in the U.S., to sell and distribute stem cell kits and equipment to veterinarians serving the nation’s fast-growing $50 billion pet industry. The announcement was made today at the Western Veterinary Conference in Las Vegas by Jeremy Delk, CEO of MediVet-America. The two companies will partner to sell and distribute MediVet-America’s advanced stem cell technology to more than 26,000 veterinary clinics nationwide. Adult animal stem cell technology uses the body’s own regenerative healing power to help treat dogs, cats, horses and other animals suffering from painful arthritis, hip dysplasia and tendon, ligament and cartilage injuries and other ailments. The Adipose-Derived Stem Cell Procedure Kit and state of the art equipment, co-developed with Medical Australia, enable veterinarians to remove a small sample of fat, separate the stem cells, then activate and inject them into affected areas. … Continue reading

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Stem cell implants boost monkeys with Parkinson's

Posted: Published on February 22nd, 2012

Monkeys suffering from Parkinson's disease show a marked improvement when human embryonic stem cells are implanted in their brains, in what a Japanese researcher said Wednesday was a world first. A team of scientists transplanted the stem cells into four primates that were suffering from the debilitating disease. The monkeys all had violent shaking in their limbs -- a classic symptom of Parkinson's disease -- and were unable to control their bodies, but began to show improvements in their motor control after about three months, Kyoto University associate professor Jun Takahashi told AFP. About six months after the transplant, the creatures were able to walk around their cages, he said. "Clear improvements were confirmed in their movement," he said. Parkinson's disease is a progressive neurological illness linked to a decrease in dopamine production in the brain. There is currently no medical solution to this drop off in a key neurotransmitter. The condition, which generally affects older people, gained wider public recognition when Hollywood actor Michael J. Fox revealed he was a sufferer. Takahashi said at the time of the implant about 35 percent of the stem cells had already grown into dopamine neuron cells, with around 10 percent still alive … Continue reading

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Celling Biosciences Sponsors 7th Annual Stem Cell Summit

Posted: Published on February 22nd, 2012

AUSTIN, Texas, Feb. 21, 2012 /PRNewswire/ -- Celling Biosciences announces a sponsorship of the 7th Annual Stem Cell Summit being held on February 21st at Bridgewaters New York in New York City. The Stem Cell Summit is consistently the premiere venue for the world's leaders in regenerative medicine to network and promote next generation technologies and cell therapies. The meeting will feature more than 30 thought leaders in stem cell therapy including Dr. Kenneth Pettine of the Orthopedic Stem Cell Institute in Loveland, Colorado.  Dr. Pettine has teamed up with Celling Biosciences' SpineSmith Division to present "Adult Stem Cell Therapy for Orthopedic and Spine Conditions Resulting from Injury or Aging."  Dr. Pettine has become an innovator in the regenerative cell therapy market and believes "regenerative therapies will become the next standard of care in treating many orthopedic conditions."  Following the Stem Cell Summit, Dr. Pettine will be presenting a discussion on regenerative therapies to the trainers and medical staff attending this year's NFL combine.  The NFL has recently gained attention from Peyton Manning going oversees to receive a cell therapy treatment for his cervical spine condition.  Dr. Pettine envisions a day when these professional athletes stop going to foreign countries to … Continue reading

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Promising new compound for treating stroke produced

Posted: Published on February 22nd, 2012

Washington, Feb 22 (ANI): A new chemical compound that has great potential for the possible treatment of brain damage caused by stroke has been designed and produced by researchers at the University of Copenhagen. The compound binds 1,000 times more effectively to the target protein in the brain than the potential drug currently being tested on stroke victims. Stroke causes the brain to release large amounts of glutamate, an activating signal compound, all at once. This overactivates the receptors in the surrounding healthy tissue, causing the level of calcium in the cells to rise dramatically. This then kick-starts a toxic chain reaction causing cell death. Scientists believe that this process is the cause of the brain damage that occurs in the wake of a stroke. Therefore they are looking for compounds that can limit cell death. "Research on animal models shows that the new compound we have designed and produced reduces the dead area in the brain after a stroke by 40 per cent. In addition, we can show that our compound is far more biologically effective than the potential drug currently being tested in clinical trials," explained Anders Bach, medicinal chemist and postdoc at the Faculty of Health and … Continue reading

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Amarantus BioSciences Presents Data on MANF at the 14th Annual Meeting of the American Society of Experimental …

Posted: Published on February 22nd, 2012

SUNNYVALE, CA--(Marketwire -02/22/12)- Amarantus BioSciences, Inc. (OTC.BB: AMBS.OB - News), a biotechnology company developing MANF, a first-in-class disease-modifying therapeutic protein being developed for the treatment of Parkinson's Disease, will present preclinical data on MANF at the 14th Annual Meeting of the American Society of Experimental Neurotherapeutics (ASENT) Conference at the Ritz Carlton Hotel in Washington, D.C. during the Pipeline session on Friday, February 24th, 2012 at 2:15pm ET. A presentation titled, "MANF: A Bi-functional Protein with Multiple Therapeutic Indications is Neuroprotective and is Upregulated in the Unfolded Protein Response," will be given by John W. Commissiong, PhD, Chief Scientific Officer of Amarantus. MANF is the company's lead drug candidate, and is one of the first potential drug candidates to be rationally discovered from an increased understanding of astrocyte-neuron biology. MANF is a novel 18 kDa, astrocyte-derived, secreted protein, with well-defined N- and C-terminal domains separated by a linker region. Prior published studies have synthesized the C-terminal domain of MANF and demonstrated that it is anti-apoptotic. Parkinson's disease is caused, in part, by apoptosis of dopaminergic neurons of the substantia nigra in the brain. "The data that will be presented demonstrate that MANF may be important in the treatment of multiple … Continue reading

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