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Archives
Monthly Archives: May 2012
Bentsen Stroke Center Awards Grants for Regenerative Medicine Research
Posted: Published on May 21st, 2012
Newswise Every year, approximately 795,000 people in the United States suffer a stroke and the late U.S. Senator and Democratic Party vice presidential candidate Lloyd Bentsen was one of them. As the senator and his wife, B. A., dealt with the challenges of stroke, they developed the idea for a stroke research center. The couples efforts led to the 2009 opening of the Senator Lloyd and B.A. Bentsen Center for Stroke Research at The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (IMM), a part of The University of Texas Health Science Center at Houston (UTHealth). Sen. Bentsen died prior to the centers opening. In April at the IMM, B.A. Bentsen and one of the couples sons, Lan, got updates on six projects funded by the stroke center. The center was launched with a generous gift from the Bentsen family and the center distributes up to $1 million annually for research. The primary focus of the Bentsen Stroke Center is to develop cell-based therapeutics, including the use of certain populations of stem cells, to reduce secondary brain injury and enhance recovery, said Brian R. Davis, Ph.D., interim director of Center for Stem Cell and Regenerative Medicine … Continue reading
Posted in Cell Medicine
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UTHealth Pediatric Surgery Expands Regenerative Medicine Program
Posted: Published on May 21st, 2012
Newswise About 3 percent of the babies born in the United States have a birth defect. Children without a birth defect are also susceptible to injury or disease. At The University of Texas Health Science Center at Houston (UTHealth), regenerative medicine researchers are exploring innovative ways to treat these conditions. The Department of Pediatric Surgery at the UTHealth Medical School operates a research program devoted to childhood conditions that is seeking to harness the bodys regenerative powers to repair malformed organs and to mitigate injury from illness or trauma. It is called the Childrens Regenerative Medicine Program. Kevin Lally, M.D., chairman of the Department of Pediatric Surgery at the UTHealth Medical School and surgeon-in-chief at Children's Memorial Hermann Hospital, announced the recruitment of four stem cell scientists to the program. The researchers are associate professor Yong Li, M.D., Ph.D., and assistant professors Scott Olson, Ph.D., Fabio Triolo, M.Phil., D.d.R., Ph.D., and Pamela Wenzel, Ph.D. We were able to recruit outstanding investigators thanks in part to the generous support of Mrs. Clare Glassell and Mrs. Evelyn Griffin, said Lally, who is the A.G. McNeese Chair in Pediatric Surgery and the Richard Andrassy, M.D., Endowed Distinguished Professor at UTHealth. Our program in … Continue reading
Posted in Cell Medicine
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Frozen cord could save a life
Posted: Published on May 21st, 2012
Tim and Padma Vellaichamy of Parramatta have had their new born child's umbilical cord stored cryogenically for future treatment. Pictured with their as yet unnamed three week old daughter. Picture: Adam Ward Source: The Daily Telegraph IT'S current preservation for future regeneration - and now umbilical cord tissue is going on ice in Australia for the first time. Usually discarded after birth, umbilical tissue from newborn babies is being collected and cryogenically frozen to be used one day for regenerative and stem cell medicine. And it doesn't just have potential for the babies involved, either. Experts say stem cells could also be used for family members who are genetically compatible. It is hoped the cells will eventually be able to be used to repair damaged tissues and organs, with researchers investigating its uses for treating diseases like multiple sclerosis, cerebral palsy and diabetes, as well as for bone and cartilage repair. Although cord blood storage has been available for many years, Cell Care Australia has added cord tissue storage in anticipation of new discoveries in the regenerative medicine field. Cell Care Australia medical director associate professor Mark Kirkland said the storage process - already popular in the US, Europe and … Continue reading
Posted in Cell Medicine
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Stem cell medicine thrown umbilical rope
Posted: Published on May 21st, 2012
Tim and Padma Vellaichamy of Parramatta have had their new born child's umbilical cord stored cryogenically for future treatment. Pictured with their as yet unnamed three week old daughter. Picture: Adam Ward Source: The Daily Telegraph IT'S current preservation for the future regeneration - and now umbilical cord tissue is going on ice in Australia for the first time. Usually discarded after birth, umbilical tissue from newborn babies is being collected and cryogenically frozen to be used one day for regenerative and stem cell medicine. And it doesn't just have potential for the babies involved, either. Experts say stem cells could also be used for family members who are genetically compatible. It is hoped the cells will eventually be able to be used to repair damaged tissues and organs, with researchers investigating its uses for treating diseases like multiple sclerosis, cerebral palsy and diabetes, as well as for bone and cartilage repair. Although cord blood storage has been available for many years, Cell Care Australia has added cord tissue storage in anticipation of new discoveries in the regenerative medicine field. Cell Care Australia medical director associate professor Mark Kirkland said the storage process - already popular in the US, Europe … Continue reading
Posted in Cell Medicine
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Family hangs hope for boy on unproven therapy in India
Posted: Published on May 21st, 2012
Indian clinic's stem cell therapy real? STORY HIGHLIGHTS For more of CNN correspondent Drew Griffin's investigation of India's experimental embryonic stem cell therapy, watch "CNN Presents: Selling a Miracle," at 8 and 11 p.m. ET Sunday on CNN. New Delhi (CNN) -- Cash Burnaman, a 6-year-old South Carolina boy, has traveled with his parents to India seeking treatment for a rare genetic condition that has left him developmentally disabled. You might think this was a hopeful mission until you learn that an overwhelming number of medical experts insist the treatment will have zero effect. Cash is mute. He walks with the aid of braces. To battle his incurable condition, which is so rare it doesn't have a name, Cash has had to take an artificial growth hormone for most of his life. His divorced parents, Josh Burnaman and Stephanie Krolick, are so driven by their hope and desperation to help Cash they've journeyed to the other side of the globe and paid tens of thousands of dollars to have Cash undergo experimental injections of human embryonic stem cells. The family is among a growing number of Americans seeking the treatment in India -- some at a clinic in the heart … Continue reading
Posted in Cell Therapy
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Opexa Therapeutics Announces TcelnaTM as New Brand Name for MS Therapy
Posted: Published on May 21st, 2012
THE WOODLANDS, Texas--(BUSINESS WIRE)-- Opexa Therapeutics, Inc. (NASDAQ:OPXA - News), a biotechnology company developing a novel T-cell therapy for multiple sclerosis (MS), announced today that the Company is rebranding its leading MS therapy with the new name TcelnaTM. The product, previously known as Tovaxin, will now be known as Tcelna as the company positions itself towards the treatment of patients with Secondary Progressive MS (SPMS). "Opexa has worked diligently in the optimization of its overall manufacturing process and clinical development program while concentrating its efforts in the SPMS indication. The rebranding of our lead product as Tcelna encompasses these advancements and our continued dedication to make a difference in the treatment of MS," commented Neil K. Warma, President and Chief Executive Officer of Opexa. The name Tcelna (pronounced Te-SELL-nuh) reflects the T-cell derivation of the product. Opexa has requested a registered trademark for the new brand name. About Opexa Opexa Therapeutics, Inc. is dedicated to the development of patient-specific cellular therapies for the treatment of autoimmune diseases such as multiple sclerosis (MS). The Companys leading therapy, TcelnaTM, a personalized cellular immunotherapy treatment, is in clinical development targeting both Secondary Progressive and Relapsing Remitting MS. Tcelna is derived from T-cells isolated … Continue reading
Posted in Cell Therapy
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Family hangs hope on unproven therapy in India
Posted: Published on May 21st, 2012
Indian clinic's stem cell therapy real? STORY HIGHLIGHTS For more of CNN correspondent Drew Griffin's investigation of India's experimental embryonic stem cell therapy, watch "CNN Presents: Selling a Miracle," at 8 and 11 p.m. ET Sunday on CNN. New Delhi (CNN) -- Cash Burnaman, a 6-year-old South Carolina boy, has traveled with his parents to India seeking treatment for a rare genetic condition that has left him developmentally disabled. You might think this was a hopeful mission until you learn that an overwhelming number of medical experts insist the treatment will have zero effect. Cash is mute. He walks with the aid of braces. To battle his incurable condition, which is so rare it doesn't have a name, Cash has had to take an artificial growth hormone for most of his life. His divorced parents, Josh Burnaman and Stephanie Krolick, are so driven by their hope and desperation to help Cash they've journeyed to the other side of the globe and paid tens of thousands of dollars to have Cash undergo experimental injections of human embryonic stem cells. The family is among a growing number of Americans seeking the treatment in India -- some at a clinic in the heart … Continue reading
Posted in Cell Therapy
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Crouse aims to zero in on drug, alcohol abuse problems and help before it's too late
Posted: Published on May 21st, 2012
Syracuse, N.Y. -- Crouse Hospital wants to nip drug and drinking problems in the bud before they destroy peoples lives. Crouse launched a random screening program earlier this year in its PromptCare urgent care center across the street from the Syracuse hospital. Its purpose is to identify patients at risk of developing serious substance abuse problems. Patients deemed to be at risk are offered on-the-spot counseling and/or referral to treatment. We want to help you at that point when theres a chance to turn things around, before you get a bad needle or before you overdose, said Tom Murphy, a chemical dependency therapist who does the screenings. The program is known as Screening, Brief Intervention, Referral and Treatment SBIRT, for short. Developed in the late 1990s at Yale New Haven Hospital, its being replicated nationwide. Research done by the federal Substance Abuse and Mental Health Services Administration shows it can help motivate people with drug and/or drinking problems to change their habits. A study done by that agency showed about 20 percent of people screened are at risk, 70 percent can be treated with a single brief intervention and the rest need follow-up services. It also found 74 percent of … Continue reading
Posted in Drug Dependency
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Manipulating Bone Healing by Drugs
Posted: Published on May 21st, 2012
Drug treatment has become one of the most important cornerstones of modern medicine, successfully influencing the course of many diseases. But in orthopedic surgery, drugs are still used surprisingly seldom. Technical advances like new fracture fixation devices and joint prostheses have revolutionized the lives of many orthopedic surgery patients. But, even today, some patients experience fractures that fail to heal, despite numerous operations, the most modern fracture devices, or bone transplants. Limb amputations are sometimes the only remaining solution in some of the most severe cases of fractures that do not knit together. Me and my fellow researchers believe that we can offer biological help in both fracture healing and in other diseases affecting bone. There are two main cell types in the bone involved during the healing of a fracture. Osteoclasts are specialized cells involved in resorption the breakdown and cleanup of dead bone in a fractured area so that new bone can be laid down. Osteoblasts are the cells responsible for the production of the new bone. A collaboration and a balance between the two are required, both for a swift response to a fracture, as well for maintenance of a functioning skeleton. Delayed healing or lack of … Continue reading
Posted in Drugs
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New Drugs from Smelling Flowers
Posted: Published on May 21st, 2012
Eighty percent of the worlds population today has access only to traditional remedies prepared from local plants as solutions for healing. Pharmaceutical research and its associated industries exploit natural products and materials to search for and prepare active ingredients for use as medicines. It is estimated that more than forty percent of the new drugs registered in the last thirty years were obtained or derived from natural sources, or were inspired by natural compounds. For centuries, humans depended exclusively on nature to find solutions for healing. The study of plant species has brought forth major contributions to medical knowledge and has lead to prototypes of major therapeutic drug classes; for example, cardiac glycosides from foxglove leaves (digitoxin), antimalarial drugs from cinchona bark (quinine), hypno-analgesic drugs from poppy latex (morphine), or anti-inflammatory drugs from white willow bark (salicylic acid). Additional studies have revealed evidence of their physiological receptors. This widespread usefulness may be related to the fact that plants, being sessile organisms, chiefly depend on their own structure and composition to achieve biological, physiological, and ecological functions as well as to adapt and survive. Plants can't move, can't yell to chase away aggressors, and can't fend off predators or parasites. So, … Continue reading
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