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Monthly Archives: May 2012
In our opinion: Editorial: Treating autism
Posted: Published on May 18th, 2012
Kelly Andrus plays with her son Bradley in his classroom at Children's Choice Learning Centers Inc., in Lewisville, Texas. Bradley, who turns three in a couple of weeks, was diagnosed a year ago with mild autism. Associated Press Enlarge photo Research into the development patterns of children with autism disorders has documented a disturbing truth that likely comes as no surprise to parents trying to nurture autistic kids into adulthood. A study by Washington University in St. Louis validates what many families have witnessed firsthand that the road to maturation is difficult and often disheartening. The study shows 35 percent of children with autism-related disorders who finish high school do not go forward with additional education or make it into the workforce. As one researcher put it, "They were just not involved in anything." It is an alarmingly large number, especially by comparison. The rate of young adults with a severe speech impairment who are not working or in school is 7 percent. For older kids with documented learning disabilities, it is 3 percent. Among those with severe mental disabilities, it is 26 percent. Why those with autism-spectrum disorders encounter roadblocks in greater proportion than others is not entirely apparent. … Continue reading
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Bridgeton autism rate above average, according to Children's Specialized Hospital study
Posted: Published on May 18th, 2012
BRIDGETON A study done by Childrens Specialized Hospital found high rates of autism in Bridgeton and five other New Jersey communities. The hospital looked at schools in Newark, Plainfield, Elizabeth, Trenton, New Brunswick and Bridgeton and asked teachers to screen for autism in preschools and day care centers. The New Jersey Governors Council for Medical Research and Treatment of Autism funded the study, which was released Wednesday. Autism, a neurodevelopment disorder, impaires social interaction and communication. Researchers looked at an initial 1,000 children in the six locations. The study found 31 children, which makes up 3 percent of the sample, to be on the autism spectrum. According to an article quoted on the Centers for Disease Control and Prevention website, studies show the national average to be 1 percent. We found that unless we go out into underserved communities, we are going to be missing many children who have autism, said Dr. Yvette Janvier, lead researcher, development/behavioral pediatrician and medical director at the Toms River Childrens Specialized Hospital. This is the first study to look at using teachers in preschools and day care centers to screen for autism. Although parents and doctors are normally used to identify children with autism, … Continue reading
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Autism Speaks plays key roles at 2012 International Meeting for Autism Research
Posted: Published on May 18th, 2012
Public release date: 16-May-2012 [ | E-mail | Share ] Contact: Jane Rubinstein jrubinstein@rubenstein.com 516-993-0708 Autism Speaks NEW YORK, N.Y. (May 15, 2012) Autism Speaks, the world's leading autism science and advocacy organization, is a major sponsor and scientific participant in the 2012 International Meeting for Autism Research (IMFAR). Organized by the International Society of Autism Research, IMFAR brings together more than 1800 scientists, clinicians, students, parents and individuals with autism from 40 countries to discuss and share the latest research into autism's causes, treatments and diagnoses. The conference is being held May 20-22 at the Sheraton Centre Toronto, 123 Queen Street West, Ontario, Canada. "Autism is a global challenge," commented Autism Speaks Chief Science Officer Geraldine Dawson, Ph.D., "and this conference offers an opportunity to bring together researchers from around the world to share their findings and collaborate, which helps accelerate research on diagnosis, causes and treatments needed by families in every country." Autism Speaks' Autism Treatment Network, a collaboration of medical centers dedicated to providing families with state of the art, multidisciplinary care, will be participating in numerous presentations throughout IMFAR. These include the technology demonstration Development of a Training Video to Teach Best Practices for Delivering An … Continue reading
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Landmark certified as primary stroke center
Posted: Published on May 18th, 2012
May 17, 2012 WOONSOCKET For the first time, municipal ambulance crews who believe their patients are suffering a stroke can deliver them to Landmark Medical Center. Thats because Landmark was certified by the Joint Commission, the nations main accrediting body of health care organizations, as a primary stroke treatment center, the hospital announced. The state Department of Health has also added Landmark to its official list of Certified Stroke Centers, enabling Landmark to treat more residents from northern Rhode Island who have suffered a stroke or who are likely to. Because of northern Rhode Islands high elderly population, and the increased likelihood of stroke for people 65 and older, Landmarks improved capability to treat patients suffering from stroke and offer rehabilitation at the Rehabilitation Hospital of Rhode Island is arriving at a crucial time, said Richard Charest, hospital president. The timing also dovetails with the proposed sale of Landmark to the Steward Health Care System, which continues to move through regulatory channels. A joint review of the merger by the attorney general and DOH under the Hospital Conversions Act is expected to be complete no later than July 17, and Health Director Michael Fine is expected to sign off any … Continue reading
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Two stem cell therapies from Cytomedix to start trials; stroke study expands
Posted: Published on May 18th, 2012
When regenerative medicine firm Cytomedix (OTC:CMXI) acquired biotechnology company Aldagen, the stem cell-based stroke treatment in clinical trials was the centerpiece of the all stock deal. Cytomedix is now making moves to develop other stem cell treatments from its Aldagen acquisition. Two more clinical trials will start later this year, CEO Martin Rosendale told analysts on a conference call to discuss first-quarter financial results. Rosendale wouldnt identify the indications that will be studied, and said only that they will be announced this summer: one for an arterial disease and the other a neurological condition. Cytomedixs goal is to ultimately find large pharmaceutical partners to commercialize these treatments. These additional clinical studies dont represent those kinds of partnerships. Rosendale said there are two facilities that will conduct investigator-led clinical trials. But those trials will be funded by outside sources, not by Cytomedix. The rest is here: Two stem cell therapies from Cytomedix to start trials; stroke study expands … Continue reading
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Cleveland: Advances in stroke treatment save lives
Posted: Published on May 18th, 2012
STROKE TERMS Stroke: Death of brain cells from interruption of their blood supply. Ischemic stroke: Blockage of an artery to the brain by a clot forming locally or traveling from the heart; accounts for 85 percent of strokes. Hemorrhagic stroke: Bleeding either within or on the surface of the brain, often due to the rupture of an aneurysm or dilated artery; accounts for 12 percent of strokes. Transient ischemic attack: Temporary reduction of blood flow to an area of the brain with reversible symptoms when flow resumes; a TIA is often a forerunner of a stroke. A middle-aged man arrives by ambulance at an emergency room at a small hospital 60 miles away from Chattanooga. Abruptly, he had lost speech and movement of his right side. The ER physician diagnoses an acute stroke and notifies the Erlanger Southeast Regional Stroke Center. An air ambulance is dispatched. Lab studies are obtained in-flight to determine if subsequent procedures will be safe. Upon arrival at Erlanger, the man embarks upon a tightly coordinated path of precise diagnosis and treatment. A series of imaging procedures shows a large area of brain at risk of death. An angiogram displays a clot within his skull, blocking … Continue reading
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InVivo Therapeutics’ CEO Frank Reynolds Scheduled to Appear on Austin News Today Weekend and Detroit’s 7 Action News …
Posted: Published on May 18th, 2012
CAMBRIDGE, Mass.--(BUSINESS WIRE)-- InVivo Therapeutics Holdings Corp. (OTC/BB: NVIV), a developer of groundbreaking technologies for the treatment of spinal cord injuries (SCI), today announced that CEO Frank Reynolds is scheduled to appear on KXAN-TVs Austin News Today Weekend on Saturday, May 19th at 7:20am CDT in Austin, TX. He is also scheduled to appear on Detroits WXYZ-TV 7 Action News on Sunday, May 20th at 8:40am EDT with local quadriplegic Drew Clayborn. Drew was paralyzed in 2010 and will join Frank on air to talk about his story and how InVivo Therapeutics treatment could change his life. InVivo Therapeutics has pioneered a new treatment using a biocompatible polymer-based scaffold to provide structural support to a damaged spinal cord. The device spares spinal cord tissue from scarring while improving functional recovery after a traumatic SCI. In addition to the scaffold and its application for acute and chronic SCI, Reynolds will discuss new hydrogel technologies under development by InVivo. Our technology is a true platform that can be leveraged to create many Neurotrauma products. InVivo is developing technologies to treat chronic injuries like Drews, as well as therapies for other nervous system conditions such as chronic pain due to nerve compression and … Continue reading
Posted in Spinal Cord Injury Treatment
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Stem Cells for Spinal Cord Injury: Some Patients Have Long-Term Improvement
Posted: Published on May 18th, 2012
Thirty Percent of Patients Show Improved Functioning after Stem Cell Therapy Philadelphia, Pa. (May 17, 2012) One of the first long-term studies of stem cell treatment for spinal cord injury shows significant functional and other improvements in three out of ten patients, reports a study in the May issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. The results support the safety of mesenchymal stem cells (MSCs) derived from the patient's own bone marrow, showing "continuous and gradual motor improvement" in at least some patients with disability caused by spinal cord injury. The lead author of the new study was Dr. Sang Ryong Jeon of University of Ulsan College of Medicine, Seoul, South Korea. Evidence of Improved Function after MSC Treatment for Spinal Cord Injury The researchers performed MSC transplantation in ten patients with permanent motor (movement) deficits or paralysis (paraplegia or quadriplegia) after spinal cord injury. Mesenchymal stem cells are a type of "multipotent" cell that can be cultured from adult bone marrow and induced to develop into many different types of cells. The cultured MSCs were injected directly into the injured … Continue reading
Posted in Spinal Cord Injury Treatment
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StemCells, Inc. Reports Positive Interim Safety Data From Spinal Cord Injury Trial
Posted: Published on May 18th, 2012
NEWARK, Calif., May 17, 2012 (GLOBE NEWSWIRE) -- StemCells, Inc. (Nasdaq:STEM - News) today announced completion of the first planned interim safety review of the Company's Phase I/II spinal cord injury clinical trial, which indicated that the surgery, immunosuppression and the cell transplants have been well-tolerated. The trial, which is designed to evaluate the safety and preliminary efficacy of the Company's proprietary HuCNS-SC(R) cells (purified human neural stem cells), represents the first time that neural stem cells have been transplanted as a potential therapeutic agent for spinal cord injury. A summary of the data will be presented by Armin Curt, M.D., principal investigator for the clinical trial, at the Interdependence 2012 Global SCI Conference, which is being held in Vancouver, British Columbia, from May 15 to 17, 2012. The interim data is from the first cohort of patients, all of whom suffered a complete spinal cord injury in which there is no neurological function below the level of the injury. All patients enrolled were transplanted with a dose of 20 million cells at the site of injury in the thoracic spinal cord. There were no abnormal clinical, electrophysiological or radiological responses to the cells, and all the patients were neurologically … Continue reading
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Ceregene Parkinson's Disease Study Demonstrates Long-term Neurturin Expression and Enhanced Dopamine Activity 4 Years …
Posted: Published on May 18th, 2012
SAN DIEGO, May 17, 2012 /PRNewswire/ -- Ceregene Inc., a biotechnology company developing treatments for neurodegenerative diseases such as Parkinson's disease, will present new data demonstrating long-term, biologically-active expression of neurturin, a nervous system growth factor delivered to the degenerating dopamine nerves in patients with Parkinson's disease following treatment with CERE-120 (AAV2-neurturin). Raymond T. Bartus, Ph.D., Ceregene's chief scientific officer and executive vice president, was invited to give a presentation entitled "The Development of AAV2-neurturin (CERE-120) for Parkinson's Disease: A Review of the Challenges and Translation Issues Confronted During the Course of Establishing 'Clinical Proof of Concept,'" at the annual meeting of the American Society for Gene and Cell Therapy during the Clinical Trials I Symposium on Thursday, May 17, 2012 in Philadelphia, PA. CERE-120 is a viral vector engineered to deliver the nervous system growth factor neurturin (NRTN), which has the ability to rejuvenate degenerating dopamine-producing neurons, restoring function and keeping them alive. NRTN has been shown to safely protect and restore damaged nigrostriatal nerves in animal models of Parkinson's disease and appears safe in humans tested in four Ceregene-sponsored clinical studies enrolling a total of 120 patients, 80 of whom were administered CERE-120. A previous double blind-controlled human … Continue reading
Posted in Parkinson's Treatment
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