Monthly Archives: May 2012

Research and Markets: Stem Cell Research Products: Opportunities, Tools & Technologies 2012 (Updated)

Posted: Published on May 15th, 2012

DUBLIN--(BUSINESS WIRE)-- Research and Markets (http://www.researchandmarkets.com/research/lffnp7/stem_cell_research) has announced the addition of the "Stem Cell Research Products: Opportunities, Tools & Technologies 2012 (Updated)" report to their offering. Stem cells are primitive cells found in all multi-cellular organisms that are characterized by self-renewal and the capacity to differentiate into any mature cell type. Several broad categories of stem cells exist, including embryonic stem cells, derived from blastocysts; fetal stem cells, obtained from aborted fetuses; adult stem cells, found in adult tissues; cord blood stem cells, isolated from umbilical tissue; dental stem cells, derived from deciduous teeth; cancer stem cells, which give rise to clonal populations of cells that form tumors or disperse in the body; and animal stem cells, derived from non-human sources. In a developing embryo, stem cells can differentiate into all of the specialized embryonic tissues. In adult organisms, stem and progenitor cells act as a repair system for the body, replenishing specialized cells. Of interest to researchers is the potential for use of stem cells in regenerative medicine to treat conditions ranging from diabetes, to cardiovascular disease and neurological disorders. Additionally, the ability to use stem cells to improve drug target validation and toxicology screening is of intense interest … Continue reading

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Research and Markets: Stem Cell Research Products: Opportunities, Tools & Technologies 2012 (Updated)

Posted: Published on May 15th, 2012

DUBLIN--(BUSINESS WIRE)-- Research and Markets (http://www.researchandmarkets.com/research/lffnp7/stem_cell_research) has announced the addition of the "Stem Cell Research Products: Opportunities, Tools & Technologies 2012 (Updated)" report to their offering. Stem cells are primitive cells found in all multi-cellular organisms that are characterized by self-renewal and the capacity to differentiate into any mature cell type. Several broad categories of stem cells exist, including embryonic stem cells, derived from blastocysts; fetal stem cells, obtained from aborted fetuses; adult stem cells, found in adult tissues; cord blood stem cells, isolated from umbilical tissue; dental stem cells, derived from deciduous teeth; cancer stem cells, which give rise to clonal populations of cells that form tumors or disperse in the body; and animal stem cells, derived from non-human sources. In a developing embryo, stem cells can differentiate into all of the specialized embryonic tissues. In adult organisms, stem and progenitor cells act as a repair system for the body, replenishing specialized cells. Of interest to researchers is the potential for use of stem cells in regenerative medicine to treat conditions ranging from diabetes, to cardiovascular disease and neurological disorders. Additionally, the ability to use stem cells to improve drug target validation and toxicology screening is of intense interest … Continue reading

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Senesco to Present SNS01-T, an eIF5A-based Nanoparticle in a Phase 1b/2a Trial to Treat Multiple Myeloma, is Effective …

Posted: Published on May 15th, 2012

BRIDGEWATER, N.J.--(BUSINESS WIRE)-- Senesco Technologies, Inc. (Senesco or the Company) (NYSE Amex: SNT), announced today that an oral presentation will be delivered at the 15th Annual Meeting of the American Society of Gene & Cell Therapy. The conference will be held May 16-19th, 2012 at the Pennsylvania Convention Center in Philadelphia, Pennsylvania. The Company will present during the Cancer-Targeted Gene & Cell Therapy Oral Abstract Session, which will begin Thursday, May 17, at 1:15 P.M. Eastern Time. The oral presentation, entitled SNS01-T, an eIF5A-Based Gene Therapy Nanoparticle Designed for the Treatment of Multiple Myeloma, has Anti-Tumoral Activity in Lymphoma, will describe the effectiveness of SNS01-T in B-cell cancers, which is designed to selectively induce programmed cell death. The talk will be delivered by Catherine Taylor who is from Senesco CSO John Thompsons research laboratory at the University of Waterloo in Ontario, Canada. About Multiple Myeloma Multiple myeloma is an incurable cancer of plasma cells, a type of white blood cell derived from B-lymphocytes, normally responsible for the production of antibodies, in which abnormal cells accumulate in the bone marrow leading to bone lesions and interfering with the production of normal blood cells. Senesco was previously granted orphan drug status for … Continue reading

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Hanover pharmacist suspended over excessive narcotics prescriptions

Posted: Published on May 15th, 2012

N.H. Board of Pharmacy has temporarily suspended the state pharmacy license of Jeffrey A. Licht after an investigation found Licht was being prescribed excessive amounts of a narcotic. Licht, a registered pharmacist, worked in Pharmacy Services at Dartmouth College Health Services, according to a staff listing on the colleges website. A Dartmouth spokesman did not respond by deadline. A professional misconduct hearing is set for 10 a.m. Wednesday at the Board of Pharmacy office at 57 Regional Drive, Concord. In an order dated May 11, the Board of Pharmacy said an investigation showed Licht diverted hydrocodone/acetaminophen from Dicks House, which is part of Dartmouth College Health Services. Hydrocodone is an opiate. Reached by phone in Hanover, Licht called the charges ludicrous. I think they will be dropped out of hand, Licht said. He said he had no attorney and would represent himself at the hearing Wednesday. Im just sorry that people become guilty before there is even a hearing. I dont have anything to say about the case except that nothing in it is true, he said. The Pharmacy Boards complaint said Licht was prescribed 9,761 tablets of hydrocodone/acetaminophen between August 2010 and March 2012 from a physician who was … Continue reading

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Effects Of ADHD – Video

Posted: Published on May 15th, 2012

14-05-2012 03:54 The effects of ADHD on a person's life, career and relationships can be disastrous especially if it is diagnosed very late. This is quite common because very often ADHD goes undiagnosed. Then there is the whole question about the effects of ADHD meds such as Ritain on a person's life as they can be very disturbing and upsetting. They are very much a two-edged sword as they can help to relieve the symptoms of restlessness and help the person or child to focus and that is really a blessing in many cases. But there are many side effects as well and that can also be problematic. But apart form the meds, the effects of ADHD are very far reaching because they prevent a person from performing according to the norms and demands of our modern society. We insist on deadlines on results and on focus. The child will more likely have problems at school and at college and that is why it is so important to teach them life coping skills and behaviour therapy to deal with behavior problems and social issues. This is the best way of lessening the effects of ADHD http See the rest here: … Continue reading

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FDA Panel Recommends Approval of Another Iffy Weight-Loss Drug

Posted: Published on May 15th, 2012

Pharmaceutical companies are rushing to produce new weight loss drugs. But some of them come along with alarming side effects. FBellon/Flickr I was riveted by an article in today's New York Times about the latest decision of an FDA drug advisory panel. The panel voted to approve a new weight-loss drug, lorcaserin. The vote was mixed: 18 for approval, four against, and one abstention. The majority felt that the benefits outweighed the risks and that even if there were risks, "new tools are needed to treat a major health problem." The benefits are worth a look. What about the risks? The drug: Also in the Times is a piece by Dr. Danielle Ofri on her experience with patients who want weight-loss drugs. She quotes from an essay called "Lemons for Obesity" by Dr. Michael S. Lauer, who was a minority voter on the FDA panel that approved the weight-loss drug Qnexa earlier this year. The weight-loss field is strewn with lemons, more so than other areas of medicine, Dr. Lauer argues. Because of the enormous potential market for these drugs -- two-thirds of American adults are overweight or obese -- pharmaceutical companies rush new drugs to market after conducting only … Continue reading

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Anti-Obesity Drugs a Hot Topic in the Biotech Industry

Posted: Published on May 15th, 2012

NEW YORK, NY--(Marketwire -05/14/12)- Biotech companies are looking to cash in on the anti-obesity drug market. The race to bring the first weight-loss pill to the market is heating up as Arena Pharmaceuticals weight-loss pill (Lorcaserin) recently gained the backing of an FDA advisory panel. The Paragon Report examines investing opportunities in the Biotech Industry and provides equity research on VIVUS, Inc. (VVUS) and Roche Holding Ltd. (RHHBY.PK). Access to the full company reports can be found at: http://www.ParagonReport.com/VVUS http://www.ParagonReport.com/RHHBY Arena is currently competing with Vivus and Orexigen Therapeutics to bring the first anti-obesity drug to the market in nearly 13 years. All three of the companies' drugs were previously turned down by the FDA. FDA advisers last week voted 18-4 that the benefits of Arena's Lorcaserin outweigh the health risks. According to recent numbers from the Center for Disease Control and Prevention over 78 million adults in the U.S. are obese. Obesity significantly raises the risks for health problems such as diabetes, heart attacks, and strokes. It is estimated that obesity costs the U.S. economy $147 billion a year in medicals costs and lost productivity. Paragon Report releases regular market updates on the Biotech Industry so investors can stay … Continue reading

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Two Powerful Drugs Can Kill Breast Cancer Cells, Says MIT

Posted: Published on May 15th, 2012

Doctors usually give breast cancer patients several cancer drugs; they claim that these drugs produce better results than treatment with just a single drug. Now researchers have found that two powerful drugs can cure breast cancer. Researchers from the Massachusetts Institute of Technology(MIT)have discovered thaterlotinib and doxorubicin have the capability to kill a particularly malignant type of breast cancer cells. Researchers had been studying complex cell-signalling pathways that control cells' behaviour: how much they grow, when they divide, when they die. In cancer, the cells grow uncontrolled and abnormally in the body. Researchers believed that the only way to switch a cancerous cell into a less malignant state is by using different combinations of cancer drugs. They tested different combinations of 10 DNA-damaging drugs and a dozen drugs that inhibit different cancerous pathways, using different timing schedules. Like us on Facebook Of all combinations they tried, they saw the best results with pretreatment using erlotinib followed by doxorubicin, a common chemotherapy agent. To prove that erlotinib and doxorubicin could kill cancer cells, the researchers conducted an experiment on mice that had tumours. A group of mice was given erlotinib and doxorubicin in different durations. Another group was given only chemotherapy … Continue reading

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`Drugs an issue in CH workforce'

Posted: Published on May 15th, 2012

EMPLOYERS in Circular Head have had trouble with drugs in the workforce, according to Mayor Daryl Quilliam. His comments come in the wake of a $300,000 cannabis bust at Smithton. "We have people that are wanting to employ people and drugs are not always an issue, but they're an issue often and people get really frustrated not knowing what to do," he said. "People employ people and they try to stress that they don't want drugs in the workforce, then a bit later they find that some of these people are on drugs. "A lot of guys that work on farms, it's an issue there. "I would think it's everywhere though to be quite honest." Cr Quilliam said it was an issue that affected most regional areas, but wasn't spoken about much. "I think drugs here are a bit like other places, they are far more prevalent than I'd like to think they would be," he said. "We're certainly concerned and would rather not have drugs involved with young people at all. "It's a shocking thing, there's no doubt about that. Excerpt from: `Drugs an issue in CH workforce' … Continue reading

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Late-Stage Drugs Are Hotbed for Co-Development and Licensing Deals

Posted: Published on May 15th, 2012

RESEARCH TRIANGLE PARK, N.C.--(BUSINESS WIRE)-- The transition from discovery and development to drug commercialization requires an entirely different set of skills, as both large and small pharmaceutical and biotech companies have found. And the costs of successfully planning and executing a global drug launch must now cover more regions and more functional groups than ever before, according to findings from consulting firm Cutting Edge Information. Complex pieces of the global launch puzzle such as regulatory submission, managed markets planning, and launch sequencing must be coordinated carefully. Each piece has a large impact on initial market reception and can drag down or drive up revenue results. These commercial steps require expertise quite different from earlier clinical trial phases; trying to shoehorn clinical experience into commercial needs invites disaster. Licensing and co-development deals can bridge the gap. Cutting Edge Informations recent study, Business Development and Licensing: Strengthening Pipelines and Managing Relationships, profiles how a development-oriented company with a promising compound primed for market, but without commercialization infrastructure, can leverage another companys experience to continue preparing the new product for launch. Collaborating with a company that has deep experience with regulatory submission and launch in major and emerging markets will save time and … Continue reading

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