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Monthly Archives: May 2012
Pharmacy Retailers: A New Suite of Services from TRICAST
Posted: Published on May 9th, 2012
MILWAUKEE, May 8, 2012 /PRNewswire/ --TRICAST, Inc. announced today that it is deploying a new suite of pharmacy program consulting services and software solutions developed specifically for pharmacy retailers. Increased concern for contract transparency requires active participation if you want to sustain strong pharmacy management. TRICAST's tools enable you to maintain this hands-on approach to PBM-vendor adjudication issues, and incorporate the oversight into your global program management strategy. "Decision-makers at retail pharmacy chains need to ask themselves three important questions," observes Rob Bigalke, Director of Business Development. "Do I have a solid understanding of the vast number of third-party contracts I already have in place? How do I track their performance? How do I use best-practice language to improve my contracts in the future?" Because pharmacy compensation is a complex, moving target, TRICAST can provide: TRICAST's sophisticated techniques provide clients with market-leading pharmacy program solutions. Our suite of software applications and comprehensive audit and consulting services can help you manage reimbursement amounts, improve overall efficiency and monitor costs. TRICAST's audit tools deliver immediate feedback on pricing and contracts/payors in compliance. Our consulting can assist with defining the range of profit and loss levels, provide guidance on ranges, and can support … Continue reading
Posted in Pharmacy
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Navigating the IP Minefield of Human Embryonic Stem Cell Development
Posted: Published on May 8th, 2012
FARMINGTON, Conn., May 8, 2012 /PRNewswire-iReach/ -- Global Information Inc. is pleased to announce two significant new reports Opportunities in Human Embryonic Stem Cell (hESC) ProductsHuman embryonic stem cells (hESCs) are stem cells derived from the inner cell mass of a blastocyst, the stage reached 4 to 5 days after fertilization. They are the most pluripotent of all stem cell types, able to develop into any of over 200 different cell types in the human body, rending them tremendously useful for their therapeutic potential. However, human embryonic stem cell research is heavily encumbered by patents held by the University of Wisconsin's Wisconsin Alumni Research Foundation (WARF), which creates significant challenges for guidance for companies seeking to develop new products. BioInformant's new Opportunities in Human Embryonic Stem Cell (hESC) Products market research report explores the complex IP landscape affecting development of human embryonic stem cell products, providing clear guidance for companies entering or already within the market. Over the past 15 years, WARF has been the major "gatekeeper" in determining which research product companies are able to conduct research, create commercial products, and develop novel therapies using hESCs. To date, WARF has entered into licensing agreements with only 27 commercial partners … Continue reading
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TiGenix : Presenting at Key Conferences – Spring 2012
Posted: Published on May 8th, 2012
LEUVEN, BELGIUM--(Marketwire -05/08/12)- TiGenix (TIG), a leader in the field of cell therapy, announced today that during the months of May and June the company will present at a number of key events in Europe and the U.S. geared at investor, industry, and academic audiences to highlight the commercial potential of ChondroCelect, the only approved cell therapy in Europe, and of the company's innovative proprietary allogeneic stem cell platform with programs in Phase I, II, and III for a range of inflammatory and autoimmune diseases. May 15-16 BioEquity, Marriott Hotel, Frankfurt, Germany Presenter: Eduardo Bravo, CEO Date & time: Tuesday, May 15, 16:00-16:25 Room: Level 1, Room Gold 1 May 21-23 World Stem Cells and Regenerative Medicine Congress, Victoria Park Plaza, London, UK Presenter: Eduardo Bravo, CEO Date & time: Monday, May 21, 15:25 -15:50 Title: Cell Therapy & Regenerative Medicine - Progressing into phase III with an orphan indication May 24 Knowledge for Growth, ICC Ghent, Belgium Presenter: Eduardo Bravo, CEO Time: 11:30 Keynote speech - Advanced therapies: this time it is for real June 5-8 18th International Stem Cell Therapy Sociey Annual Meeting, Sheraton Seattle, WA, U.S. Presenter: Eduardo Bravo, CEO Date & time: June 7, 13:45-15:15 Title: … Continue reading
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FDA: Celgene Drug Revlimid Increases Risk Of Certain New Cancers
Posted: Published on May 8th, 2012
By Jennifer Corbett Dooren, Of DOW JONES NEWSWIRES WASHINGTON -(Dow Jones)- The Food and Drug Administration said certain patients treated with Celgene Corp.'s (CELG) cancer drug Revlimid have an increased risk of developing some new types of cancers. Revlimid is approved to treat patients with multiple myeloma, a bone-marrow cancer in combination with another drug. The product is also approved to treat another bone-marrow condition called myelodysplastic syndromes. In a drug-safety communication posted to the FDA's website Monday, the agency said data from clinical trials of Revlimid showed newly diagnosed patients treated with Revlimid had an increased risk of developing second types of cancer compared to similar patients who received a placebo, or fake drug. The agency said there was an increased risk of developing acute myelogenous leukemia, a type of blood cancer, myelodysplastic syndromes and Hodgkin lymphoma. The FDA said the information has been added to Revlimid's label, which is aimed at giving information about products to doctors, and that patient information is being updated. The FDA said doctors "should consider both the potential benefit of Revlimid and the risk of second primary malignancies when deciding to treat patients with this drug, and monitor patients for this risk." Patients … Continue reading
Posted in FDA Stem Cell Trials
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NY medical schools chart progress with stem cells
Posted: Published on May 8th, 2012
ALBANY, N.Y. (AP) -- Almost halfway through a $600 million state program supporting stem cell research, eight medical schools around New York are reporting progress on projects such as replicating liver cells and eradicating leukemia cells. A new report from Associated Medical Schools of New York updates work at the institutions where hundreds of researchers are starting to unravel causes and potential treatments for conditions ranging from autism to heart disease and cancer. Stem cells are self-renewing and have the ability to develop into other types of cells. The Mount Sinai School of Medicine reported finding a method to transform human skin cells into stem cells and turned differentiated human stem cells into heart cells. Those findings are expected to result in better understanding of how heart disease develops and allow initial testing of new treatments on stem cells before they are used on human subjects. Dr. Ihor Lemischka, director of the Black Family Stem Cell Institute at Mount Sinai, said recreating heart cells in a dish from a patient with LEOPARD Syndrome, a disease caused by a genetic mutation, has opened ongoing avenues for researching the disease and screening potential drugs. "It was a major achievement," Lemischka said. The … Continue reading
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Treatment spares Lebanon man from amputation
Posted: Published on May 8th, 2012
LEBANON Retired Dartmouth College professor Roger Smith said he had nothing to lose by joining a stem cell therapy clinical trial. In fact, if he didn't join, he did have something to lose possibly his leg. In the end it appears the experiment saved his leg. And Smith, who'd already lost two toes to amputation, said he's proud to have played a part in a study that could dramatically improve the outcome for many other patients facing lower-limb amputations resulting from diabetes, high cholesterol, smoking, genetic predisposition and other causes. The three-year study that ended last year was led by vascular surgeons at Dartmouth-Hitchcock Medical Center in Lebanon, who believe the treatment may offer new hope to sufferers of peripheral artery disease, a condition that causes nearly 60,000 lower-limb amputations every year. Dr. Richard J. Powell, chief of vascular surgery at Dartmouth-Hitchcock, was the lead investigator of the second-phase national study, which included 72 patients from 20 different sites across the United States. It's a winner, Powell said. For me, it was dramatic, because there has been nothing that has been shown to work. The results of the third-stage trial are to be presented to the Food and Drug Administration … Continue reading
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Neuralstem Updates ALS Stem Cell Trial Progress
Posted: Published on May 8th, 2012
ROCKVILLE, Md., May 8, 2012 /PRNewswire/ --Neuralstem, Inc. (CUR) announced that the Federal Drug Administration (FDA) has approved the return of three patients from earlier cohorts in its ongoing Phase I safety trial to treat amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) with its spinal cord stem cells (HSSC's). These patients will be permitted to return to the trial for second treatments as the next cohort of patients, provided they meet inclusion requirements at the scheduled time. They will be the first to receive stem cell transplantation along the length of the spinal cord. (Logo: http://photos.prnewswire.com/prnh/20061221/DCTH007LOGO ) The first twelve patients in the trial, which is taking place at Emory University Hospital in Atlanta, Georgia, received stem cell transplants in the lumbar (lower back) region of the spinal cord only. Thelast cohort of three, completed in April, received transplants in the cervical (upper back) region of the spinal cord, where stem cell transplantation could help support breathing, a key function that is lost as ALS progresses. The next cohort of three patients is designed to receive 10 HSSC injections in the lumbar region and 5 in the cervical, for a total of 15 injections along the length of the … Continue reading
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Iranian researcher helps treating muscular dystrophy using stem cells
Posted: Published on May 7th, 2012
Source: ISNA, Tehran Iranian researcher and lecturer Radbod Darabi jointly with his collogues from the University of Minnesota's Lillehei Heart Institute have effectively treated muscular dystrophy in mice using human stem cells derived from a new process which for the first time makes the production of human muscle cells from stem cells efficient and effective. Radbod Darabi, MD, PhD with Rita Perlingeiro, PhD. (Credit: Image courtesy of University of Minnesota Academic Health Center) The research outlines the strategy for the development of a rapidly dividing population of muscle-forming cells derived from induced pluripotent (iPS) cells. IPS cells have all of the potential of embryonic stem (ES) cells, but are derived by reprogramming skin cells. They can be patient-specific, which renders them unlikely to be rejected, and do not involve the destruction of embryos. This is the first time that human stem cells have been shown to be effective in the treatment of muscular dystrophy. According to the researchers, there has been a significant lag in translating studies using mouse stem cells into therapeutically relevant studies involving human stem cells. This lag has dramatically limited the development of cell therapies or clinical trials for human patients. The latest research from the … Continue reading
Posted in Muscular Dystrophy Treatment
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treatment for autism – defeat autism now – treatments for autism – Video
Posted: Published on May 7th, 2012
06-05-2012 17:05 - treatment for autism - defeat autism now - treatments for autism He was affected very strongly by his social surroundings, and his emotions overloaded him every minute. Here's what I did to help, and here's what I've got to offer you. autism help resources for autism autism specialist autism treatment center autism teaching strategies cures for autism See the article here: treatment for autism - defeat autism now - treatments for autism - Video … Continue reading
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autism help – resources for autism – autism specialist – Video
Posted: Published on May 7th, 2012
06-05-2012 17:06 - autism help - resources for autism - autism specialist Due to all parents having extremely busy lifestyles, it can become like just another chore to have to listen and breakdown our children's. Daily experiences and issues, and even then we may struggle to have the right words. treatment for autism defeat autism now treatments for autism autism treatment center autism teaching strategies cures for autism See more here: autism help - resources for autism - autism specialist - Video … Continue reading
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