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Monthly Archives: July 2012
Homemade drugs frustrating police
Posted: Published on July 2nd, 2012
GRAND FORKS - When Andrew Spofford was arrested by Grand Forks police last month, he told them he is a "hobby chemist." Police say the end result of his chemistry was a synthetic drug that appears to have killed two teens in the area and sent several others to the hospital with overdoses. Its a growing problem for law enforcement as investigators struggle to identify a myriad of new synthetic drugs. Knowledge of basic chemistry has allowed drug cooks to make small molecular changes to existing drugs, creating new substances and keeping the cooks a step ahead of investigators. We are seeing a continued influx of changing of chemical compounds that make up various drugs or substances being ingested throughout the state, said Drew Evans, senior special agent with the Minnesota Bureau of Criminal Apprehension. They are changing at the molecular level into something it wasnt before, but may have similar effects or different effects. His agency investigated the East Grand Forks, Minn., death of Elijah Stai, 17, of Park Rapids, on June 15. The agencys labs concluded Stai had ingested a psychedelic substance called 25iNBOMe, which law enforcement officials allege Spofford cooked. The same batch of drugs allegedly killed … Continue reading
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People's Pharmacy: Medical flip-flops frustrate consumers
Posted: Published on July 2nd, 2012
Q: I am fed up with all the conflicting advice about how to stay healthy. One day vitamin D is great; the next, experts say it doesn't work for bones. I have also seen flip-flops about eggs, salt, calcium, fluoride and hormone replacement therapy. A: We understand your frustration. Americans have been told for decades to cut back on eggs even though recent research shows they do not raise cholesterol. There is a raging controversy about the wisdom of widespread salt restriction (American Journal of Hypertension, January 2012). Risks associated with calcium supplements (Heart, June 2012) and hormone replacement therapy (Annals of Internal Medicine online, May 28, 2012) just add to the confusion. You can't go wrong with Grandma's wisdom: exercise, vegetables and a good night's sleep. Q: I used to have ingrown toenails. I had them removed by surgery (not the whole nail). Now my nails have a really bad fungal infection. What can I do? A: Trauma can sometimes trigger fungal infections in the nails. Prescription pills to treat nail fungus can have serious side effects, including liver damage. There are a number of home remedies that you might try first, but you'll need to be patient. It … Continue reading
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Gorham police make arrest in pharmacy robbery
Posted: Published on July 2nd, 2012
Cumberland County Jail Gorham police made an arrest on Sunday in connection with a pharmacy robbery reported earlier in the day. The Community Pharmacy at 365 Main St. in Gorham reported an armed robbery in progress at 8:38 a.m., Lt. Chris Sanborn of Gorham Police said in a release. A man later identified as John J. Vernon Jr. demanded all the Oxycodone in the pharmacy. He fled the pharmacy with Oxycodone and was caught a short time later by Gorham police, Sanborn said. Pharmacy theft is an increasing problem fro Maine law enforcement Sanbord said "This is a huge of problem for the state of Maine," Sanborn said. "At this point in time in the state of Maine we've already exceeded the number of armed robberies in pharmacy's for prescription medications past what we had for robberies last year. It's a huge problem and its definitely that both the state and local law enforcement need to get together and try to address before we actually have some people that are hurt." Vernon, 28, of Saco, has been charged with three counts of armed robbery as well as theft, terrorizing, eluding an officer, reckless conduct with a dangerous weapon, criminal speed … Continue reading
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Researcher hunts for sickle cell anemia cure
Posted: Published on July 1st, 2012
Halfway around the world in India, Sivaprakash Ramalingam had heard of Johns Hopkins researchers using a promising new technique for gene therapy that he hoped to integrate with stem cells to cure diseases. After getting a doctorate in biochemistry in his native country, he came to Baltimore four years ago to study under the technique's pioneer, Srinivasan Chandrasegaran, at Hopkins' Bloomberg School of Public Health. Ramalingam's research has led him down the path of seeking a cure for sickle cell anemia, a painful, life-shortening blood disorder that afflicts many in his home region in southern India. In the United States, the disease affects 70,000-100,000 people, mostly African-Americans, according to the National Heart Lung and Blood Institute. "I couldn't have done this type of research in India," said Ramalingam. "I wanted to use this technique with stem cells to treat disease." Ramalingam's research was given a lift last month by the state. He was one of 17 researchers who was funded by the Maryland Stem Cell Research Commission, a state entity that has doled out roughly $10 million to $12 million a year in taxpayer funds since its founding in 2006. The program helps keep Maryland competitive in stem cell research … Continue reading
Posted in Stem Cell Human Trials
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FOXO1 gene may play important role in Parkinson's disease
Posted: Published on July 1st, 2012
ScienceDaily (June 29, 2012) A recent study led by researchers at Boston University School of Medicine (BUSM) revealed that the FOXO1 gene may play an important role in the pathological mechanisms of Parkinson's disease. These findings are published online in PLoS Genetics, a peer-reviewed open-access journal published by the Public Library of Science. The study was led by Alexandra Dumitriu, PhD, a postdoctoral associate in the department of neurology at BUSM. Richard Myers, PhD, professor of neurology at BUSM, is the study's senior author. According to the Parkinson's Disease Foundation, 60,000 Americans are diagnosed with Parkinson's disease each year and approximately one million Americans are currently living with the disease. Parkinson's disease is a complex neurodegenerative disorder characterized by a buildup of proteins in nerve cells that lead to their inability to communicate with one another, causing motor function issues, including tremors and slowness in movement, as well as dementia. The substantia nigra is an area of the midbrain that helps control movement, and previous research has shown that this area of the brain loses neurons as Parkinson's disease progresses. The researchers analyzed gene expression differences in brain tissue between 27 samples with known Parkinson's disease and 26 samples from … Continue reading
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Parkinson’s Researcher Fabricated Data
Posted: Published on July 1st, 2012
Neuroscientist Mona Thiruchelvam, formerly at the University of Medicine and Dentistry, New Jersey, agrees to retract two studies based on fake cell count data. A former assistant professor at the University of Medicine and Dentistry, New Jersey (UMDNJ) committed research misconduct by fabricating data, according to an investigation by the university and the Department of Health and Human Services Office of Research Integrity (ORI). The ORI, which announced its findings on Thursday (June 28), determined that Mona Thiruchelvam falsified cell count data published in two papers in 2009 in Environmental Health Perspectives and Journal of Biological Chemistry, both of which she has agreed to retract. Thiruchelvam fabricated stereological cell count data in two studies on how pesticides influence neuronal mechanisms involved in Parkinsons disease (PD). The studies reported the results of 13 new experiments that supposedly counted nigrostriatal neurons in the brains of mice and rats, but an investigation spearheaded by the UMDNJ determined those counts were never taken. The nigrostriatal pathway is a major dopamine circuit in the brain, and loss of neurons in this area is one of the main features of Parkinsons disease. The papers slated for retraction investigate the neurological response to the combined pesticides paraquat … Continue reading
Posted in Cell Medicine
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Downtown Pharmacy in St. John's gets new licence, reopens
Posted: Published on July 1st, 2012
St. John's pharmacist Paul Gill of Downtown Pharmacy has temporarily lost his licence. CBC (CBC) Downtown Pharmacy in St. John's reopened on Friday after being closed for two months following its licence being revoked. The Pharmacy Board of Newfoundland and Labrador said it cancelled the business licence of Downtown Pharmacy on the west end of Water Street after the pharmacist-in-charge stepped down in May. The closure forced 110 people who rely on the site for methadone to seek help elsewhere. The board issued a new licence to Downtown Pharmacy after the drugstore met a number of conditions, including having a second pharmacist on staff. Don Rowe, the secretary-registrar of the board, said the pharmacy is once again able to dispense methadone, but he doesn't known how many of its previous patients will return. The owner of the building, pharmacist Paul Gill is not allowed to work there. He was disciplined by the board in April for not properly supervising one of his staff, pharmacist Ann Marie Burke. See more here: Downtown Pharmacy in St. John's gets new licence, reopens … Continue reading
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