Cardiology | Department of Pediatrics | University of Washington

Leadership

Mark B. Lewin, MD Professor Division Chief

The Division of Cardiology is based at Seattle Childrens and provides both outpatient and inpatient consultation and management services for pediatric patients with cardiovascular disorders. Clinical and basic research are ongoing, with laboratory investigation leading to improvement in our understanding of how the immature heart uses oxygen and other fuels, mechanisms of action in the pathophysiology of Kawasaki disease, drug therapy in Marfan syndrome and pulmonary hypertension, innovations in interventional cardiac catheterization, among others.

The Division of Cardiology is based at Seattle Childrens and provides both outpatient and inpatient consultation and management services for pediatric patients with cardiovascular disorders. Cardiovascular services at Seattle Children's operate under the umbrella of Seattle Children's Heart Center and include:

Diagnostic and follow-up care Seattle Clinic - based at Seattle Childrens Regional Clinics - Bellevue, Everett, Federal Way, Olympia, Tri-Cities Outreach Clinics - Multiple sites in Washington, Montana and Alaska

Advanced non-surgical treatment Diagnostic Catheterization Interventional (Therapeutic) Catheterization Procedures

Arrhythmia diagnosis and treatment Electrocardiograms (ECGs) 24 Hour Holter Monitoring Cardiac Event Monitoring Tilt testing Stress testing Pacemaker Implantation and Monitoring Transcatheter Ablation Therapy Cardio-Pulmonary Exercise Testing

Comprehensive ultrasound evaluation Transthoracic Echocardiography Transesophogeal Echocardiography Fetal Echocardiography (within the Prenatal Diagnosis and Treatment Program) Stress Echocardiography Echocardiographic Telemedicine

Pediatric cardiac intensive care team 24 Hour intensive care for cardiac surgical and cardiology patients

Early, one-stage corrective surgery Neonatal Open and Closed Heart Procedures Pediatric Open and Closed Heart Procedures

Seattle Childrens Outpatient Services UWMC Outpatient Services UWMC Inpatient Consultation

Basic research in our laboratory continues to improve understanding of how the immature heart uses oxygen and other fuels. This knowledge will help us to develop strategies to protect the heart during and after surgery for congenital heart disease.

Myocardial energy metabolism and myocardial protection continue as the primary research endeavors within the Cardiology Division. Basic laboratory research focuses on the signals, which communicate to the cells energy factory, the mitochondrion, during increases in heart work. Thyroid hormone levels decrease after artificially induced stresses such as cardiac surgery. Protocols involving supplementation of thyroid hormones after cardiac surgery in infants have begun to show the importance thyroid hormone balance after cardiopulmonary bypass. Thus, research in our experimental laboratory now complements clinical research at Seattle Childrens.

We also have a number of outcomes research projects. These include a multicenter study of adult congenital heart disease, an NIH-sponsored drug trial in patients with Marfan syndrome, and studies associated with the post-natal outcomes after the prenatal diagnosis of specific cardiac anomalies. We participate in multicenter trials surrounding patients with pulmonary hypertension, and are an international leader in device trials in the cardiac catheterization laboratory.

The pediatric cardiology fellowship program currently consists of two fellows per year.

For more information, please visit the Cardiology Fellowship page.

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Cardiology | Department of Pediatrics | University of Washington