Category Archives: BioInformatics

EMBL-EBI: Celebrating 20 years of bioinformatics In 2014, the European Molecular Biology Laboratory (http://www.embl.org) turns 40 and its UK site, the European Bioinformatics Institute (http://www.ebi.ac.uk), turns 20. This film features... By: emblmedia … Continue reading →

Richardson, Texas and Delft, The Netherlands (PRWEB) September 08, 2014 Bluebee, a next generation sequencing data analysis provider, and Convey Computer Corporation, the leader in hybrid-core computing for accelerating data analytics, today announced a distribution agreement that strengthens both companies bioinformatics offerings. The partnership promotes increased innovation for bioinformatics technologies and advanced solutions for next-generation sequencing research. The distribution agreement allows Convey to resell the Bluebee Genome Analytics solution, enabling Convey to expand its offering in the bioinformatics and life sciences domain. The agreement also enables Bluebee to incorporate the existing Convey bioinformatics components into its integrated pipeline of high-performance, computer-based tools for whole-genome diagnostics. Conveys bioinformatics suite is made up of a number of personalities including the Convey GraphConstructor for de novo short read assembly, Smith-Waterman for local sequence alignment, and Burrows-Wheeler Aligner for fast reference mapping. The implementation of these algorithms on Conveys innovative hybrid-core architecture has demonstrated impressive performance gains compared to commodity clusters. Bluebee is currently extending its offering to include an accelerated BWA MEM algorithm for aligning long query reads, as well as a variant calling module on Conveys hybrid-core server architecture. These new solutions will allow geneticists to get more accurate information faster, which … Continue reading →

Balti and Bioinformatics "On-Air" The popular Balti and Bioinformatics series returns, this time in virtual space! Join us for a nanopore-themed programme which will be streamed from Google H... By: Nick Loman … Continue reading →

DALLAS, September 4, 2014 /PRNewswire/ -- According to the new market research report "Next Generation Sequencing (NGS) Market by Platforms (Illumina HiSeq, MiSeq, HiSeqX Ten, NextSeq 500,Thermo Fisher Ion Proton/PGM), Bioinformatics (Exome Sequencing, RNA-Seq, ChIP-Seq), Technology (SBS, SMRT) & by Application (Diagnostics, Personalized Medicine)-Global Forecast to 2020", published by MarketsandMarkets, the global NGS Market will be worth $2.5 Billion by the end of 2014 and is poised to reach $8.7 Billion by 2020 at a CAGR of more than 20.0%. Browse 130 market data tables with 52 figures spread through242 pages and in-depth TOC on"Next Generation Sequencing (NGS) Market". http://www.marketsandmarkets.com/Market-Reports/next-generation-sequen ... Early buyers will receive 10% customization on this report. This report studies the global NGS market over the forecast period of 2014-2020. The growth of the overall NGS Market is driven by continuous innovations and developments in the market aimed at higher throughput, increased accuracy, and affordable costs. The cost for whole genome sequencing has reached the much awaited $1,000 mark as claimed by the market leader Illumina. The opportunities for the growth of this market include developments in pre-sequencing, cloud computing, and NGS bioinformatics solutions. However, factors such as high reliability on grants and funding from the government … Continue reading →

Michael Stitzel joked that his research has led him to climb up the evolutionary tree. As an undergraduate he worked with yeast, and over the years, he has worked his way up to studying Drosophila, C. elegans, and, now, people. Stitzel shifted from the more basic roots of the tree to the biomedical limbs as a matter of motivation. He said that as a graduate student, though he worked on an important and interesting question, when experiments didn't go well, it was hard for him to get motivated. And so, he found himself drawn to questions with more direct relevance to medicine. He turned to studying type 2 diabetes. Using a genome-wide association study approach, he identified a number of regions in the genome linked to the disease, but many of them were, as he put it, "in the middle of nowhere." This led him to thinking about epigenetics, and then to later uncover what he and his colleagues dubbed 'stretch enhancers,' longer-than-average enhancers that appear to be driving physiological functions. Read the rest here: Funding Update: NIH Bioinformatics Grants Awarded July 10 Sept. 2, 2014 … Continue reading →

Biotechnology and Genomics, part 4 DNA sequencing and Bioinformatics By: Rene Fester Kratz … Continue reading →

Bioinformatics is a field that has been developing over the last thirty years. It is a discipline that represents a marriage between biotechnology and computer technologies and has evolved through the convergence of advances in each of these fields. Today bioinformatics is a field that encompasses all aspects of the application of computer technologies to biological data. Computers are used to organize, link, analyze and visualize complex sets of biological data. With the advent of high throughput technologies such as Next Generation Sequencing and proteomics, bioinformatics has become essential to the biological sciences in general. In the past, laboratories were able to manage and analyze their experimental data in spreadsheets. Many research labs now require the expertise of dedicated bioinformatics core centers or their own in-house bioinformaticists. Graduates of our programs have entered such laboratories, both in industry and academia, as bioinformaticists. Some have also gone on to leverage their biotechnology experiences as wet lab experimentalists themselves. The diversity of skills our students cultivate has given them access to a wide range of career choices. If you are interested in becoming a key player in the pivotal role of a bioinformaticist, please read more on our site through the links … Continue reading →

Bioinformatics and Genomics Graduate Program Graduate students and alumni talk about what they like about the Huck Institute's Bioinformatics and Genomics Graduate Program. By: Huck Institutes of the Life Sciences … Continue reading →

Michael Stitzel joked that his research has led him to climb up the evolutionary tree. As an undergraduate he worked with yeast, and over the years, he has worked his way up to studying Drosophila, C. elegans, and, now, people. Stitzel shifted from the more basic roots of the tree to the biomedical limbs as a matter of motivation. He said that as a graduate student, though he worked on an important and interesting question, when experiments didn't go well, it was hard for him to get motivated. And so, he found himself drawn to questions with more direct relevance to medicine. He turned to studying type 2 diabetes. Using a genome-wide association study approach, he identified a number of regions in the genome linked to the disease, but many of them were, as he put it, "in the middle of nowhere." This led him to thinking about epigenetics, and then to later uncover what he and his colleagues dubbed 'stretch enhancers,' longer-than-average enhancers that appear to be driving physiological functions. Go here to see the original: Augusts Bioinformatics Papers of Note … Continue reading →

Michael Stitzel joked that his research has led him to climb up the evolutionary tree. As an undergraduate he worked with yeast, and over the years, he has worked his way up to studying Drosophila, C. elegans, and, now, people. Stitzel shifted from the more basic roots of the tree to the biomedical limbs as a matter of motivation. He said that as a graduate student, though he worked on an important and interesting question, when experiments didn't go well, it was hard for him to get motivated. And so, he found himself drawn to questions with more direct relevance to medicine. He turned to studying type 2 diabetes. Using a genome-wide association study approach, he identified a number of regions in the genome linked to the disease, but many of them were, as he put it, "in the middle of nowhere." This led him to thinking about epigenetics, and then to later uncover what he and his colleagues dubbed 'stretch enhancers,' longer-than-average enhancers that appear to be driving physiological functions. Link: Q&A: Istvan Albert on Penn State's Efforts to Equip Biomedical Researchers to Use Bioinformatics Tools … Continue reading →