Category Archives: Brain Injury Treatment

UC Research Looking Into Young People With Brain Injury Who May Later Offend April 22, 2013 Young people who suffer traumatic brain injury can have behavior problems and a University of Canterbury (UC) adjunct professor is investigating whether there is evidence of increased risk of offending behavior among this group of people. Falls are the most common source of traumatic brain injury (TBI) for children under 15 and fights, sporting injuries and motor vehicle accidents are the most common forms of TBI for those over 15. The UC research is in collaboration with Monash University in Melbourne. Monashs Dr Audrey McKinlay, who is a UC adjunct, says the major objective is to investigate the number of young people who, following a TBI in childhood, later suffer mental disorders, attention deficit hyperactivity disorder (ADHD), conduct disorder, mood disorders, substance abuse or anxiety. ``These disorders are associated with an increased risk of offending behaviour, so we also want to find out whether there is evidence of increased offending behaviour among this population, Dr McKinlay says. ``TBI accounts for over three percent of all hospital admissions and costs the Accident Compensation Corporation around $100 million a year for post-acute treatment and rehabilitation. Therefore, … Continue reading →

Young people who suffer traumatic brain injury can have behavior problems and a University of Canterbury (UC) adjunct professor is investigating whether there is evidence of increased risk of offending behavior among this group of people. Falls are the most common source of traumatic brain injury (TBI) for children under 15 and fights, sporting injuries and motor vehicle accidents are the most common forms of TBI for those over 15. The UC research is in collaboration with Monash University in Melbourne. Monashs Dr Audrey McKinlay, who is a UC adjunct, says the major objective is to investigate the number of young people who, following a TBI in childhood, later suffer mental disorders, attention deficit hyperactivity disorder (ADHD), conduct disorder, mood disorders, substance abuse or anxiety. These disorders are associated with an increased risk of offending behaviour, so we also want to find out whether there is evidence of increased offending behaviour among this population, Dr McKinlay says. TBI accounts for over three percent of all hospital admissions and costs the Accident Compensation Corporation around $100 million a year for post-acute treatment and rehabilitation. Therefore, the development of interventions aimed at reducing adverse outcomes will have a major cost benefit. A … Continue reading →

Public release date: 19-Apr-2013 [ | E-mail | Share ] Contact: Carolann Murphy CMurphy@KesslerFoundation.org 973-324-8382 Kessler Foundation West Orange, NJ. April 18, 2013. Kessler Foundation is one four sites participating in "Quality of Life in Caregivers of Traumatic Brain Injury: The Development of the TBI-CareQOL", a multi-site 5-year study funded by the National Institutes of Health/National Institute of Nursing Research (1R01NR013658-01). Nancy Chiaravalloti , PhD, co-investigator of the Kessler site, is also project director of the Northern New Jersey Traumatic Brain Injury System and director of TBI Research at Kessler Foundation. The University of Michigan is the lead center for the study; Noelle Carlozzi, PhD, is principal investigator. The goal is to develop a measure of quality of life that is specific to caregivers of persons with traumatic brain injury (TBI). Although these caregivers have been identified as an underserved population in both civilian and in military life, there is a lack of measures of health-related quality of life (HRQOL) that are specific to these caregivers. "This study will result in a new tool that will help clinicians understand the issues these caregivers face," said John DeLuca, PhD, VP for Research and Training, "and identify the need for additional treatment … Continue reading →

Newswise William Meehan, MD, is the first recipient of the AMSSM Foundation-ACSM Foundation Clinical Research Grant for his research titled "A Randomized, Double-Blind, Placebo-Controlled Trial of Transcranial Light Emitting Diode Therapy for the Treatment of Chronic Concussive Brain Injury. The latest in a series of collaborative projects between the American Medical Society for Sports Medicine and the American College of Sports Medicine, the joint Clinical Research Grant Committee selects a single proposal to receive a $20,000 award. The partnership calls for an initial three-year commitment for the annual joint clinical research grant awards. We are pleased to have received 22 highly competitive grant proposals, making it challenging to select only one recipient, said Suzanne Hecht, MD, who chaired the review committee and serves as AMSSM Research Committee chair. The scientific quality of these proposals is a reflection of both organizations commitment to the advancement of sports medicine research. Dr. Hecht added, The clinical research grant committee recognizes the potential of Dr. Meehans proposal to develop into a new treatment for patients who suffer prolonged sports-related concussions. Dr. Meehan is an assistant professor of pediatrics at Harvard Medical School and serves as the director of the Micheli Center for Sports Injury … Continue reading →

Sponsorship includes integration of GTX Corp into the professional sports sector in effort to provide innovative solutions for Traumatic Brain Injury while enhancing brand exposure of GTXs product line LOS ANGELES, CA and NEW YORK, NY - GTX Corp (OTCBB:GTXO.OB), a leader in customizable, patented 2-way GPS solutions, and Brewer Sports International (BSI), a multi-faceted global sports management firm with a focus on consulting, event management and sports lending, announced today that they have aligned their partnership with the professional sports industry in effort to maximize GTXs brand and market awareness of their diverse product line. This initiative will launch with GTX Corps sponsorship of the upcoming NFL Draft Week Experience series of events hosted by BSI to take place from Tuesday, April 23 Thursday, April 25 surrounding the National Football League (NFL) Draft this week in New York, NY. Through their strategic partnership with BSI, GTX will have the opportunity to highlight their brand including various innovative solutions for Traumatic Brain Injury (TBI) through a series of events taking place during the 2013 NFL Draft week involving numerous current and former professional athletes including Super Bowl Champions, top draft picks, NFL veterans and celebrities in the sports, music and … Continue reading →

Investigational Treatment for Mild Traumatic Brain Injury to be Studied in Phase I Trial Later This Year BANGKOK, April 18, 2013 /PRNewswire-USNewswire/ --Besins Healthcare (Besins) and Shin Nippon Biomedical Laboratories (SNBL), a global leader in hormonal products, announced today that they have completed a licensing agreement to use SNBL's proprietary intranasal drug delivery system, Muco System, to further develop its BHR-310 investigational agent containing progesterone for treating mild traumatic brain injury (TBI). Under the terms of the licensing agreement, Besins gains access to SNBL's delivery technology, along with associated patents and know-how for delivery of progesterone. Besins will be responsible for completing the development of the product, seeking regulatory approval and commercializing the product. SNBL will be entitled to certain undisclosed milestone payments and royalties on sales. "The overwhelming need for a treatment for concussions or mild TBI cannot be overstated," said Thomas W. MacAllister, JD, PhD, Besins Chief Development Officer. "The condition is a huge unmet medical need, especially in theaters of war and on sports fields. Partnering with SNBL will allow us to quickly accelerate our intranasal progesterone research program. They have a tremendous amount of expertise in nasal delivery and the platform we are licensing gives far … Continue reading →

ROCKVILLE, Md., April 18, 2013 /PRNewswire/ --Neuralstem, Inc. (NYSE MKT: CUR) announced that CEO and President, Richard Garr, will take part in a comprehensive Bio Maryland panel, introduced by Lt. Governor, Anthony Brown, on Maryland's leadership in traumatic brain injury prevention, diagnosis and treatment at the BIO International Convention in Chicago, Ill., on April 24. Mr. Garr's panel, from 2:30 3:30, will discuss "TreatmentWhat's Working and What is Under Development." He will focus on NSI-189, Neuralstem's lead neurogenic compound, which is currently in a Phase Ib clinical trial in major depressive disorder (MDD). In animal models of depression, NSI-189 significantly increased the generation of new neurons in the hippocampus, a part of the brain that atrophies in patients who have major depression and which could also be implicated in brain injury. Mr. Garr will also talk about the potential of NSI-189 to be used in the treatment of traumatic brain injury (TBI). (Logo: http://photos.prnewswire.com/prnh/20061221/DCTH007LOGO) About Neuralstem Neuralstem's patented technology enables the ability to produce neural stem cells of the human brain and spinal cord in commercial quantities, and the ability to control the differentiation of these cells constitutively into mature, physiologically relevant human neurons and glia. Neuralstem completed an FDA-approved … Continue reading →

Public release date: 15-Apr-2013 [ | E-mail | Share ] Contact: Allison Elliott allison.elliott@uky.edu University of Kentucky LEXINGTON, Ky. (April 15, 2013) Even a mild injury to the brain can have long lasting consequences, including increased risk of cognitive impairment later in life. While it is not yet known how brain injury increases risk for dementia, there are indications that chronic, long-lasting, inflammation in the brain may be important. A new paper by researchers at the University of Kentucky Sanders-Brown Center on Aging (SBCoA), appearing in the Journal of Neuroscience, offers the latest information concerning a "switch" that turns "on" and "off" inflammation in the brain after trauma. A team of researchers led by Linda Van Eldik, director of SBCoA, used a mouse model to study the role of p38a MAPK in trauma-induced injury responses in the microglia resident immune cell of the brain. "The p38 MAPK protein is an important switch that drives abnormal inflammatory responses in peripheral tissue inflammatory disorders, including chronic debilitating diseases like rheumatoid arthritis," said Van Eldik. "However, less is known about the potential importance of p38 MAPK in controlling inflammatory responses in the brain. Our work supports p38 MAPK as a promising clinical target … Continue reading →

Apr. 15, 2013 Even a mild injury to the brain can have long lasting consequences, including increased risk of cognitive impairment later in life. While it is not yet known how brain injury increases risk for dementia, there are indications that chronic, long-lasting, inflammation in the brain may be important. A new paper by researchers at the University of Kentucky Sanders-Brown Center on Aging (SBCoA), appearing in the Journal of Neuroscience, offers the latest information concerning a "switch" that turns "on" and "off" inflammation in the brain after trauma. A team of researchers led by Linda Van Eldik, director of SBCoA, used a mouse model to study the role of p38a MAPK in trauma-induced injury responses in the microglia resident immune cell of the brain. "The p38 MAPK protein is an important switch that drives abnormal inflammatory responses in peripheral tissue inflammatory disorders, including chronic debilitating diseases like rheumatoid arthritis," said Van Eldik. "However, less is known about the potential importance of p38 MAPK in controlling inflammatory responses in the brain. Our work supports p38 MAPK as a promising clinical target for the treatment of CNS disorders associated with uncontrolled brain inflammation, including trauma, and potentially others like Alzheimer's disease. … Continue reading →

April 13, 2013 Updated Apr 13, 2013 at 7:12 PM EDT Every 18.5 seconds, someone suffers from a brain injury. In fact, 1.7 million Americans are currently living with a brain injury. A large group gathered Saturday afternoon at Westwood Lanes for "Bowling for Brain Injuries." Indiana was chosen as one of five states to kick off this inaugural fundraiser. Fort Wayne was a chosen city, along with Indianapolis, because of the large support groups it has. The event aims to raise money for the advancement of brain injury prevention, research, treatment and education. A board member of the Brain Injury Association of Indiana, Kristin Smith, says a brain injury can affect every aspect of one's life, from emotions and feelings, to motor skills. And she says brain injuries are such a big problem because it can happen to anyone. Smith says babies can get a brain injury from Shaken Baby Syndrome, a high school athlete can suffer one from having a concussion, and even senior citizens who fall and hit their head may suffer. Nebraska was the first state to host a "Bowling for Brain Injury" event. The state raised about $34,000, and Smith says Indiana wants to up … Continue reading →