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Category Archives: Brain Injury Treatment

Researchers link left-sided brain injury with greater risk for hospital-acquired infections

Posted: Published on March 1st, 2013

Feb. 28, 2013 Findings published in the March issue of Archives of Physical Medicine & Rehabilitation have implications for translational research into brain-mediated immune defenses, infection control practices and cognitive rehabilitation strategies after stroke and brain injury. West Orange, NJ. February 28, 2013. The March 2013 issue of Archives of Physical Medicine & Rehabilitation, the medical journal of the American Congress of Rehabilitation Medicine, features an article by Kessler researchers Pasquale Frisina, PhD, Ann Kutlik, BA, and A.M. Barrett, MD. The study, "Left-sided brain injury associated with more hospital-acquired infections during inpatient rehabilitation," has implications for further research into brain-mediated immune defenses, infection control practices and cognitive rehabilitation strategies to improve outcomes after stroke and traumatic brain injury. The study was supported by Kessler Foundation and the National Institutes of Health (grant nos. R01NS055808, K24HD062647). The authors, a team of stroke specialists from Kessler Foundation and Kessler Institute for Rehabilitation, report findings of a retrospective study of 2236 inpatients with brain lesions caused by traumatic brain injury or stroke. Hospital-acquired infection (HAI), a common complication that adversely affects outcomes and costs, was defined as infection diagnosed within 48 to 72 hours of admission. Of the 163 patients identified as having … Continue reading

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Traumatic Brain Injury (TBI) Legal Resource For People Seeking Legal Options Unveiled at LawsuitLegal.com

Posted: Published on March 1st, 2013

People who have suffered traumatic brain injuries can now learn more about their legal options with a new information resource unveiled by LawsuitLegal.com. The injured can now speak with a real lawsuit attorney and get answers in reference to their injury claim regardless of their location. Fort Lauderdale, FL (PRWEB) February 28, 2013 The regularly updated support information is now available at the official website, and both the injured party and the family of the victim qualify for the legal review being made available. To get help, visitors need only fill out a few details relating to their case using a secure, 100% confidential online form that takes less than 2 minutes to complete. Following the completion of a request a real attorney will review the details and respond as soon as possible. "Our guarantee to you is that you will be treated with the dignity and respect you deserve. Not all cases have merit under the eyes of the law, but everyone deserves to be heard," stated Christopher M. Levin with LawsuitLegal.com. According to the Centers for Disease Control and Prevention (CDC) an estimated 1.7 million people suffer a brain injuries that are traumatic in nature each year in … Continue reading

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Support offered for brain injury survivors

Posted: Published on March 1st, 2013

ATKINSON The Brain Injury Association of NH provides Support Group Meetings for brain injury and stroke survivors for the greater Salem/Derry area. A brain injury can be a result of trauma, stroke or other brain disorders. This group meets regularly on the first Tuesday of every month. The next meeting will be held Tuesday. The meetings are held at the Community Crossroads, 8 Commerce Drive in Atkinson from 6:30 to 8 p.m. For more information, call Terri Cadorette at (603) 893-1299, Ext. 321. Derry library welcomes teens DERRY Derry Public Library offers Cafe Days for teens March 5 and 19, April 2, 16 and 30, and May 14, from 3:30 to 4:30 p.m. in Meeting Room A. Its an open forum format with warm drinks. Teens share ideas, brainstorm future programs or share artwork in personal sketch books. The meetings are open to all teens. On Tuesday, representatives from Next Charter School will drop in to answer any questions people may have about the school. All are welcome to attend. Go here to see the original: Support offered for brain injury survivors … Continue reading

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Kessler researchers link left-sided brain injury with greater risk for hospital-acquired infections

Posted: Published on March 1st, 2013

Public release date: 28-Feb-2013 [ | E-mail | Share ] Contact: Carolann Murphy CMurphy@KesslerFoundation.org 973-324-8382 Kessler Foundation West Orange, NJ. February 28, 2013. The March 2013 issue of Archives of Physical Medicine & Rehabilitation, the medical journal of the American Congress of Rehabilitation Medicine, features an article by Kessler researchers Pasquale Frisina, PhD, Ann Kutlik, BA, and A.M. Barrett, MD. Left-sided brain injury associated with more hospital-acquired infections during inpatient rehabilitation (http://dx.doi.org/10.1016/j.apmr.2012.10.012) has implications for further research into brain-mediated immune defenses, infection control practices and cognitive rehabilitation strategies to improve outcomes after stroke and traumatic brain injury. The study was supported by Kessler Foundation and the National Institutes of Health (grant nos. R01NS055808, K24HD062647). The authors, a team of stroke specialists from Kessler Foundation and Kessler Institute for Rehabilitation, report findings of a retrospective study of 2236 inpatients with brain lesions caused by traumatic brain injury or stroke. Hospital-acquired infection (HAI), a common complication that adversely affects outcomes and costs, was defined as infection diagnosed within 48 to 72 hours of admission. Of the 163 patients identified as having hospital-acquired infections, 60.1% had left-sided lesions. This finding was consistent with the hypothesis that a left-dominant brain immune network (LD-BIN) may … Continue reading

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Amarantus BioScience and Banyan Biomarkers to Present Poster of MANF Data at The 3rd Annual Traumatic Brain Injury …

Posted: Published on February 25th, 2013

SUNNYVALE, Calif. and ALACHUA, Fla., Feb. 25, 2013 /PRNewswire/ --Amarantus BioScience, Inc. (AMBS), a biotechnology company discovering and developing treatments and diagnostics for diseases associated with neurodegeneration and apoptosis centered around its patented therapeutic protein MANF, and Banyan Biomarkers, the leader in developing in vitro diagnostic products to detect TBI, today announced that the companies will be making a joint poster presentation March 6-7, 2013 at The 3rd Annual Traumatic Brain Injury (TBI) Conference in Washington, DC (www.tbiconference.com). The poster is entitled "Mesencephalic astrocyte-derived neurotrophic factor (MANF) neuroprotection from necrotic and apoptotic cell death in rat cortical cultures." "MANF significantly inhibited caspase and calpain-mediated cellular processes of cell death and conferred overall neuroprotection in our cellular model systems of TBI," said Dr. Juan Martinez, Director of Scientific Operations at Banyan Biomarkers. "This neuroprotection indicates therapeutic potential based on well-defined biochemical pathway inhibition. We look forward to working with Amarantus to further develop MANF's therapeutic potential in TBI." About Mesencephalic-Astrocyte-derived Neurotrophic Factor (MANF) MANF (Mesencephalic-Astrocyte-derived Neurotrophic Factor) is a protein that corrects protein misfolding, one of the major causes of apoptosis (Programmed Cell Death). Mesencephalic-Astrocyte-derived Neurotrophic Factor (MANF) is believed to have broad potential because it is a naturally-occurring protein produced … Continue reading

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Lpath to Present Data at Arrowhead's 3rd Annual Traumatic Brain Injury Conference on March 7, 2013

Posted: Published on February 25th, 2013

SAN DIEGO, CA--(Marketwire - Feb 25, 2013) - Lpath, Inc. ( NASDAQ : LPTN ), the industry leader in bioactive lipid-targeted therapeutics, has been invited to present data from its Lpathomab program in models of central nervous system injury, including traumatic brain injury (TBI), at Arrowhead's 3rd Annual Traumatic Brain Injury Conference. Lpathomab is a first-in-class monoclonal antibody that binds to and neutralizes lysophosphatidic acid (LPA), a bioactive lipid that has been implicated in neuropathic pain, neurotrauma, and various other disorders. Lpath's vice president and founder, Roger Sabbadini, Ph.D., will present at the Sheraton Crystal City Hotel in Washington, DC on March 7, 2013, at 11:15 a.m. Eastern time. He will discuss a study entitled, "Monoclonal Anti-lysophosphatidic Acid Antibodies Are Neuroprotective after Experimental TBI." The study is part of a collaboration between Lpath and scientists at the University of Melbourne (Alice Pebay, Ph.D. and Peter Crack, Ph.D.), UCLA Brain Injury Research Center (Neil Harris, Ph.D.), and University of Kentucky (Andrew Morris, Ph.D.). The presentation will demonstrate that: (i) LPA receptors are increased after human brain injury; (ii) LPA levels are upregulated in the cerebrospinal fluid of TBI patients; (iii) Lpathomab administered systemically (single dose post-injury) in mouse models of TBI … Continue reading

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Cannabinoid Trans-Caryophyllene Protects Brain Cells From Ischemia

Posted: Published on February 24th, 2013

Editor's Choice Academic Journal Main Category: Stroke Article Date: 24 Feb 2013 - 0:00 PST Current ratings for: Cannabinoid Trans-Caryophyllene Protects Brain Cells From Ischemia 5 (1 votes) 5 (1 votes) TC is derived from the essential oils of the Cannabis sativa plant, but its structure is very different to other classical cannabinoids - it is not associated with any psychoactive side effects. Researchers conducted tests in both in vivo and in vitro animal models and found that TC is successfully able to protect brain cells from ischemia. Brain ischemia occurs when there is a lack of blood flow to the brain, this can sometimes lead to irreversible damage in the form of vascular dementia. It can be quite deadly, according to researchers from the University of California - Los Angeles, around 62% of ischemic stroke patients are re-hospitalized within 12 months and 15% die within a month of being hospitalized. In cell cultures consisting of oxygen deprived rat cortical neurons and glia, TC reduced neuronal injury and mitochondrial depolarization. The lead author of the study, Won-Ki Kim, PhD, of the Department of Neuroscience, College of Medicine, Korea University in Seoul, said: The study is the first of its kind … Continue reading

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Heads Up Alaska: Community Support

Posted: Published on February 23rd, 2013

ANCHORAGE - Jeffry Kellerman suffered a traumatic brain injury (TBI) almost 25 years ago when his car veered off the road and hit a ditch in Butte, Alaska. A lot of things were seriously damaged including my head. My face was crushed on the right side. The upper palate cracked all the way around and I had a large enough crack in on my forehead to where they didn't have to remove anything from my skull to release pressure off of my brain. And then at that point it was just getting me to survive everything else in the meantime, said Kellerman. He said recovery really didnt begin until he discovered support groups for people living with traumatic brain injures. It was just a major relief to be in a group in a room with other people who understood. And words need not be said in that group. Just walking into the room was like I am with familiar people, he explained. Jim Beck, Executive Director of Access Alaska, said having a TBI can be isolating. It can be a really really lonely place to be and thats one of the things that peer support does. It makes you realize … Continue reading

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WUSTL Researcher Gets Get $2.25 Million Grant to Better Understand Traumatic Brain Injury

Posted: Published on February 23rd, 2013

Newswise Washington University in St. Louis engineering researchers have received a five-year, $2.25 million grant to better understand traumatic brain injuries in efforts to improve methods for prevention and treatment. Philip Bayly, PhD, the Lilyan and E. Lisle Hughes Professor of Mechanical Engineering and chair of the Department of Mechanical Engineering & Materials Science, is principal investigator of the grant from the National Institutes of Health (NIH). The grant will allow Bayly and his research team to develop 3-D computer models of brain biomechanics that will give researchers and clinicians a better understanding about what happens to the brain during traumatic brain injury. Previously, Bayly and his research team measured brain motion and mechanical properties of the brain in 2-D. Head injuries, concussions and the resulting trauma have been in public discussion recently as the National Football League (NFL) deals with a lawsuit regarding head injuries by about one-third of living former NFL players. The league is accused of not providing information connecting football-related head injuries to brain damage, memory loss and other long-term health issues. We are concerned about everyone who hits their head, Bayly says. Its not only a factor for NFL players, but anyone whos had a … Continue reading

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WUSTL researcher gets $2.25 million grant to better understand traumatic brain injury

Posted: Published on February 23rd, 2013

Public release date: 22-Feb-2013 [ | E-mail | Share ] Contact: Neil Schoenherr nschoenherr@wustl.edu 314-935-5235 Washington University in St. Louis Washington University in St. Louis engineering researchers have received a five-year, $2.25 million grant to better understand traumatic brain injuries in efforts to improve methods for prevention and treatment. Philip Bayly, PhD, the Lilyan and E. Lisle Hughes Professor of Mechanical Engineering and chair of the Department of Mechanical Engineering & Materials Science, is principal investigator of the grant from the National Institutes of Health (NIH). The grant will allow Bayly and his research team to develop 3-D computer models of brain biomechanics that will give researchers and clinicians a better understanding about what happens to the brain during traumatic brain injury. Previously, Bayly and his research team measured brain motion and mechanical properties of the brain in 2-D. Head injuries, concussions and the resulting trauma have been in public discussion recently as the National Football League (NFL) deals with a lawsuit regarding head injuries by about one-third of living former NFL players. The league is accused of not providing information connecting football-related head injuries to brain damage, memory loss and other long-term health issues. "We are concerned about everyone … Continue reading

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