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Category Archives: Cardiac Remodeling

Denervation Therapy Ventures Where Drugs Have Failed: HFpEF – Medscape

Posted: Published on October 14th, 2020

Denervation by catheter ablation, having broached the drug-intensive world of hypertension with some success, is venturing into a clinical realm that has repeatedly crushed attempts at medical therapy: heart failure with preserved ejection fraction (HFpEF). Continue reading

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FUNDC1 interacts with FBXL2 to govern mitochondrial integrity and cardiac function through an IP3R3-dependent manner in obesity – Science Advances

Posted: Published on September 19th, 2020

INTRODUCTION Sustained obesity prompts ample chronic noncommunicable diseases such as insulin resistance, type 2 diabetes mellitus, coronary heart disease, hypertension, atherosclerosis, and stroke, resulting in high cardiovascular disease morbidity and mortality (1). Obesity is associated with unfavorable myocardial structural and functional changes accompanied by mitochondrial injury, a pathological condition commonly known as obesity cardiomyopathy (25). Continue reading

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3D curvature-instructed endothelial flow response and tissue vascularization – Science Advances

Posted: Published on September 19th, 2020

INTRODUCTION The human vasculature forms a complex three-dimensional (3D) architecture spanning a large range of diameter, curvature, and torsion to provide efficient perfusion and tissue oxygenation. Its structure continues to adapt and remodel throughout life to meet changing energy demands in both regeneration and disease progression. The sources of vascular remodeling, however, remain elusive, partially due to the complex and heterogeneous vascular structure found in vivo and the lack of tools to recapitulate them in vitro Continue reading

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Microengineered 3D pulmonary interstitial mimetics highlight a critical role for matrix degradation in myofibroblast differentiation – Science…

Posted: Published on September 15th, 2020

INTRODUCTION Fibrosis is implicated in nearly 45% of all deaths in the developed world and plays a role in numerous pathologies, including pulmonary fibrosis, cardiac disease, atherosclerosis, and cancer (1). In particular, interstitial lung diseases, such as idiopathic pulmonary fibrosis (IPF), are fatal and incurable with a median survival of only 2 to 5 years (2) Continue reading

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Pulmonary Hypertension in HFpEF and HFrEF: JACC Review Topic of the Week – DocWire News

Posted: Published on August 31st, 2020

This article was originally published here J Am Coll Cardiol. 2020 Sep 1;76(9):1102-1111 Continue reading

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Global Absorbable Heart Stent Market Covid-19 Impact Analysis, Leading Player, Application, New Product Developments and 2024 Forecast – The Daily…

Posted: Published on August 31st, 2020

The research study Absorbable Heart Stent market 2020 available by ABRReports.com provides the detailed insights about factors affecting the market growth as well as detailed analysis of the market structure along with forecast of the various segments and sub-segments of the global market Access the PDF Sample Copy of the report at https://www.abrreports.com/industry-insights/global-absorbable-heart-stent-industry-market-research-2019?form=request-report-sample The objective of the Study: The key purpose of the study to track and analyze competitive developments such as joint ventures, strategic alliances, mergers and acquisitions, new product developments, and research and developments in the global Absorbable Heart Stent market. The report provides historical and forecast revenue of the market segments and sub-segments with respect to four main geographies and their countries- North America, Europe, Asia, Latin America and the Rest of the World. The study delivers country-level analysis of the market with respect to the current market size and future perspective as well as country-level analysis of the market for segment by application, product type, and sub-segments country-level analysis of the market for segment by application, product type, and sub-segments Access full research report with Table of Content at https://www.abrreports.com/industry-insights/global-absorbable-heart-stent-industry-market-research-2019 Key market segmentation as below: Key players in global Absorbable Heart Stent market include: Abbott Laboratories Biotronik Arterial Remodeling Technologies Amaranth Medica Kyoto Medical Planning Elixir Medical Corporation Reva Medical Market segmentation, by product types: Polymer Metal Market segmentation, by applications: Metal Cardiac Centers Other Market segmentation, by regions: North America Europe Asia Pacific Middle East & Africa Latin America In this report, we analyze the Absorbable Heart Stent industry from two aspects. Continue reading

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Business Notebook: Several ‘pro-business’ laws now in effect; SEMO joins forces with Codefi – Southeast Missourian

Posted: Published on August 31st, 2020

The Missouri Chamber of Commerce and Industry is touting what it says are several pro-business laws passed by the Missouri Legislature and signed into law by Gov. Mike Parson. The new laws, which became effective Friday, include: * Legislation calling for a major change to Missouri's legal climate the chamber says will "stop the abuse of Missouri's punitive damage system." * A bill changing the state's occupational-licensing laws, allowing skilled professionals who are already licensed in another state to come to Missouri and enter the workforce Continue reading

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EphrinA1-Fc Attenuates Ventricular Remodeling and Dysfunction in Chronically Nonreperfused WT but not EphA2-R-M mice – DocWire News

Posted: Published on August 28th, 2020

This article was originally published here Int J Mol Sci. 2020 Aug 13;21(16):E5811. Continue reading

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Adverse Remodeling in Atrial Fibrillation Following Isolated Aortic Valve Replacement Surgery – DocWire News

Posted: Published on August 28th, 2020

Background Atrial fibrillation (AF) is the most common arrhythmia with adverse clinical outcomes. Aortic valve replacement (AVR) is one of the most frequently performed cardiac surgeries, although there is scarce evidence on arrhythmic outcomes Continue reading

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Impact of sex on timing and clinical outcome of septal myectomy for obstructive hypertrophic cardiomyopathy – DocWire News

Posted: Published on August 28th, 2020

This article was originally published here Int J Cardiol. 2020 Aug 22:S0167-5273(20)33642-1. doi: 10.1016/j.ijcard.2020.08.059. Continue reading

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