Category Archives: Cell Medicine

Contact Information Available for logged-in reporters only Newswise Two new gifts from The Eli and Edythe Broad Foundation to UCLA totaling $4 million will fund research in stem cell science and digestive diseases and support the recruitment of key faculty at two renowned research centers. The gifts bring to $30 million The Broad Foundation's total support of faculty recruitment and basic and translational research at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA and at the Center for Inflammatory Bowel Diseases at UCLA's Division of Digestive Diseases. A $2 million gift to the Broad Stem Cell Research Center adds to The Broad Foundation's original 2007 gift of $20 million, which has supported faculty and research and launched the Innovation Award program, which furthers cutting-edge research at the center by giving UCLA stem cell scientists "seed funding" for their research projects. The new gift will enable the continuation of the award program, which has yielded a 10-to-1 return on investment with grantees securing additional funding from other agencies, including the National Institutes of Health and more than $200 million in total grants from the California Institute for Regenerative Medicine, the state's stem cell agency. … Continue reading →

The entire heart muscle in young children may hold untapped potential for regeneration, new research suggests. For decades, scientists believed that after a child's first few days of life, cardiac muscle cells did not divide. Instead, the assumption was that the heart could only grow by having the muscle cells become larger. Cracks were already appearing in that theory. But new findings in mice, scheduled for publication in Cell, provide a dramatic counterexample -- with implications for the treatment of congenital heart disorders in humans. Researchers at Emory University School of Medicine have discovered that in young mice 15 days old, cardiac muscle cells undergo a precisely timed spurt of cell division lasting around a day. The total number of cardiac muscle cells increases by about 40 percent during this time, when the rest of the body is growing rapidly. [A 15-day-old mouse is roughly comparable to a child in kindergarten; puberty occurs at day 30-35 in mice.] The burst of cell division is driven by a surge of thyroid hormone, the researchers found. This suggests that thyroid hormone could aid in the treatment of children with congenital heart defects. In fact, doctors have already tested thyroid hormone supplementation in … Continue reading →

Contact Information Available for logged-in reporters only Newswise BETHESDA, MD, MAY 7, 2014If cells were cars, then the three pioneering cell biologists just named winners of the 2014 E.B. Wilson Medal, the highest scientific honor of the American Society for Cell Biology, helped write the essential parts list. William Bill Brinkley of the Baylor College of Medicine in Houston, John Heuser of the Washington University School of Medicine in St. Louis, and Peter Satir of the Albert Einstein College of Medicine in the Bronx identified crucial pieces of the cytoskeleton, the cells shape-shifting framework, and showed how these elements drive life at the cellular level. Named for Edmund Beecher Wilson (1856-1939), Americas first modern cell biologist, the Wilson Medal will be presented to the winners in December at the ASCBs 54th Annual Meeting in Philadelphia. We selected these three people because of their lifetime contributions to the field of cell biology, particularly to the study of the cytoskeleton, says Joseph Gall, of the Carnegie Institution of Washington, who chaired the Wilson Medal selection committee for ASCB. The E.B. Wilson is the highest award given by the ASCB and it means a great deal to ASCB members, who recognize that our … Continue reading →

Contact Information Available for logged-in reporters only Newswise (Denver, Colo.) In human medicine a gold standard of diagnosis and prognosis for numerous cancers has involved cytogenetic (linking the study of genetic inheritance with the study of cell structure) assessment of the tumor cells. Within the past few years scientists have demonstrated that characteristic cytogenetic changes associated with human cancers are shared in corresponding canine cancers. Researchers are now exploring the broader use of cytogenetics in veterinary oncology as a means to advance clinical management and treatment options for cancers affecting pet dogs. To pursue this first required the development of key reagents and tools specific for use with canine specimens, says Dr. Matthew Breen, a North Carolina State University College of Veterinary Medicine professor of genomics. Breen will address the 2014 ACVIM Forum attendees Wednesday, June 4 from 10:0511:45 a.m. at the Gaylord Opryland Resort & Convention Center in Nashville with presentations titled, Genomics & Genetics in Veterinary Medicine: An Overview and Cancer in the Domestic Dog: A Genome With Two Tales, detailing the latest advances in the field. Breens laboratory has developed an extensive cytogenetics toolbox designed to provide the necessary means to identify key cytogenetic signatures in numerous … Continue reading →

Los Angeles, CA (PRWEB) May 05, 2014 Tennis elbow is a common condition affecting 40-60 years aged adults. Though it is not a critical condition, it is potentially disabling in the sense that it restricts the certain activities of tennis players. MetroMD Institute of Regenerative Medicine, Los Angeles, offers an innovative treatment with PRP- Platelet Rich Plasma- a minimally invasive procedure. The therapy takes fewer months for rehabilitation and correct elbow injury in a way that traditional methods cannot do. Source: Dr. Alex Martin - MetroMD Institute of Regenerative Medicine, 7080 Hollywood Blvd, Los Angeles, California. Tennis elbow is caused by repetitive strain to the tendon in the elbow. Consequently, due to the overuse and strain, elbows have damaged ligaments in the area. Scientifically, this condition is known as lateral epicondylitis. MetroMD, LA, treats vastitude of players with tennis elbow with a minimally invasive procedure with less time for rehabilitation. Dr. Alex Martin, Medical Doctor at the Institute, introduces the latest technologies in regenerative medicine - prolotherapy and platelet-rich plasma treatment (PRP) is one of them. The therapy involves the use of stem cells harvested from the patients bone marrow along with PRP and re-injecting the derived concentrated solution to … Continue reading →

Malaysia to open new budget airport in MH370 shadow Sepang (Malaysia) (AFP) - Malaysia this week opens what it calls the world's largest airport built specifically for low-cost airlines, a project driven by budget travel's phenomenal growth but which debuts under the shadow of missing flight MH370. The $1.2 billion facility near the main Kuala Lumpur International Airport (KLIA) was originally targeted to open three years ago but has been hit by repeated delays, amid concerns over safety and subpar construction, even as costs have doubled. But the new KLIA2 budget terminal will begin operations Friday with an initial 56 flights, increasing the load as airlines move full operations over from a nearby existing facility in coming days. Its modern design features soaring ceilings, natural lighting, people-mover belts and improved connectivity with access to an existing express airport train to Kuala Lumpur 50 kilometres (31 miles) away. Read more here: Cesca Executive Management Meets With Key Congressional Leaders on the Regenerative Medicine Promotion Act of 2014 … Continue reading →

Malaysia to open new budget airport in MH370 shadow Sepang (Malaysia) (AFP) - Malaysia this week opens what it calls the world's largest airport built specifically for low-cost airlines, a project driven by budget travel's phenomenal growth but which debuts under the shadow of missing flight MH370. The $1.2 billion facility near the main Kuala Lumpur International Airport (KLIA) was originally targeted to open three years ago but has been hit by repeated delays, amid concerns over safety and subpar construction, even as costs have doubled. But the new KLIA2 budget terminal will begin operations Friday with an initial 56 flights, increasing the load as airlines move full operations over from a nearby existing facility in coming days. Its modern design features soaring ceilings, natural lighting, people-mover belts and improved connectivity with access to an existing express airport train to Kuala Lumpur 50 kilometres (31 miles) away. Go here to read the rest: Bioheart, Inc. Presented Clinical Trial Results at the Age Management Medicine Group Conference … Continue reading →

PUBLIC RELEASE DATE: 29-Apr-2014 Contact: Mark Derewicz mark.derewicz@unch.unc.edu 919-923-0959 University of North Carolina Health Care CHAPEL HILL, N.C. Researchers in the UNC School of Medicine found that the protein DAZAP1 plays a key role in the regulation of many genes through a process known as alternative splicing, and when highly expressed in cancer cell line experiments, DAZAP1 was shown to inhibit several types of cancer cells from dividing and moving. The discovery, published in the journal Nature Communications, marks the first time this little-known protein has been characterized in relation to cancer development and tumor growth. "If you knock down DAZAP1, then most of the genes involved in specific cancer cell signaling, cell death, and DNA repair are affected," said Rajarshi Choudhury, PhD, a postdoctoral research associate in the department of pharmacology and first author of the study. "It's a domino effect. DAZAP1 seems to be a sort of master regulator." The protein regulates how genes are spliced together before the genes produce the proteins that are involved in causing cancer cells to grow and divide. When there's a lot of DAZAP1, cancer cells cease proliferating. "We've seen this in six different types of human cancer cell lines in the … Continue reading →

Malaysia to open new budget airport in MH370 shadow Sepang (Malaysia) (AFP) - Malaysia this week opens what it calls the world's largest airport built specifically for low-cost airlines, a project driven by budget travel's phenomenal growth but which debuts under the shadow of missing flight MH370. The $1.2 billion facility near the main Kuala Lumpur International Airport (KLIA) was originally targeted to open three years ago but has been hit by repeated delays, amid concerns over safety and subpar construction, even as costs have doubled. But the new KLIA2 budget terminal will begin operations Friday with an initial 56 flights, increasing the load as airlines move full operations over from a nearby existing facility in coming days. Its modern design features soaring ceilings, natural lighting, people-mover belts and improved connectivity with access to an existing express airport train to Kuala Lumpur 50 kilometres (31 miles) away. Read more from the original source: Cell Analysis Market by Instruments (Flow Cytometer, Microscope, Microfluidics, QPCR), Consumables, Application (Cell ... … Continue reading →

Durham, NC (PRWEB) April 23, 2014 Stress could activate "crosstalking" cell signals that decrease the bodys natural healing process after a wound occurs, according to a new study released today in STEM CELLS Translational Medicine. The finding helps explain how stress impairs healing and, conversely, could lead to a way to overcome chronic wounds resulting from serious burns and other skin injuries. Chronic wounds are a major global health problem, with annual costs in the United States alone of more than $23 billion, said Roslyn Isseroff, M.D., of the University of California Davis and the Northern California Health Care Systems Department of Veterans Affairs. She was a lead investigator in the study along with Mohan R. Dasu, Ph.D. The precise process that prevents their healing is unclear except for two constants: a prolonged inflammatory response and the bacterial colonization of the wound bed. These two interrelated factors are thought to contribute to the wounds chronic state. Previous studies had demonstrated an increase in epinephrine (adrenaline), as occurs during stress, produces an increase in the activity of TLR2 (Toll-like receptor 2), a protein that appears to stimulate the early inflammatory process needed to set the steps of healing in motion. Together … Continue reading →