Category Archives: Hormone Replacement Therapy

Taking hormone replacement therapy soon after menopause starts wont protect against memory problems or other signs of cognitive decline that occurs with aging, according to a new analysis of a landmark clinical trial published online Monday in the journal JAMA Internal Medicine. It also, though, wont harm brain function in middle-aged women who take hormone therapy to relieve menopausal hot flashes, night sweats, and mood swings. Thats reassuring news to those seeking menopausal symptom relief from hormone therapy but may also be worried about previous research showing that hormones speed cognitive decline and increase the risk of dementia in elderly women. Researchers from the Brigham and Womens Hospital and elsewhere relied on data from more than 1300 female participants, ages 50 to 55, who were randomly assigned to take HRT for an average of seven years as part of the Womens Health Initiative clinical trial. Cognitive testingperformed about seven years after the trial endedfound no differences in memory, problem-solving, or learning skills in those who took hormone therapy and those who took placebos. What the latest analysis didnt address is whether taking hormones right at the onset of menopausewhen symptoms occur-- have any benefits or risks in terms of cognitive … Continue reading →

NEW YORK (Reuters Health) - Hormone replacement therapy during the early stages of menopause - typically around age 50 - doesn't hurt or help brain function, according to a new study. Researchers found that women between the ages of 50 and 55 years old who took estrogen or estrogen with progesterone performed just as well on tests that measure memory problems as women of the same age who took a placebo. "Our findings are that we didn't see any long term impact on cognitive function," said Mark Espeland, the study's lead author, from the Wake Forest School of Medicine in Winston-Salem, North Carolina. Previous studies had found that women 65 years old and older suffered lasting memory problems when they used hormone therapy to treat symptoms of menopause, such as hot flashes, vaginal dryness and trouble sleeping. Imaging tests even found that the brains of those older women assigned to hormone therapy had become smaller, compared to those who took a placebo. Currently, the government-backed U.S. Preventive Services Task Force recommends that postmenopausal women avoid hormone replacement therapy due to increased risks of heart disease, stroke, breast cancer and dementia. Some research, however, has suggested there may be a "window … Continue reading →

By Serena Gordon HealthDay Reporter WEDNESDAY, June 26 (HealthDay News) -- Although there has been significant debate about whether calcium and vitamin D supplements are beneficial for older women, new research suggests that the answer may be yes for those who are taking hormone replacement therapy. Women using HRT who also took daily supplements of calcium and vitamin D saw a 40 percent reduction in their rate of hip fractures compared to women who took placebo supplements, according to the study. "We found that women who were on hormones had less hip fractures, and women who were on hormones and calcium and vitamin D supplements had even fewer hip fractures," said study author Dr. John Robbins, a professor of medicine at the University of California at Davis. Results of the study were published online June 26 in the journal Menopause. As many as half of all women over 50 will have an osteoporosis-related fracture in their lifetime, according to the U.S. Preventive Services Task Force (USPSTF). Osteoporosis is a condition caused by a loss of bone mass and density, which leaves bones fragile and more susceptible to fractures. Calcium is an important component in bone growth, and vitamin D helps … Continue reading →

MIAMI - Although many women are frightened by concerns of a potential link between hormone replacement therapy and cancer or heart disease, some are re-evaluating that risk in the light of new conclusions. Maria Venereo said she was hesitant to undergo hormone replacement therapy at first. "I heard a lot of stories and reading about it and all that, I said, yeah, I'll put it off, I'll put it off," she said. "[I] try a few things, natural stuff, didn't work." Venereo turned to Cooper City midwife Karen Bosia for guidance and found reassurance. "I personally take estrogen every day, and I've been taking it for 12 years and I don't plan on stopping it," said Bosia. Bosia said the conventional belief that hormone replacement therapy is dangerous is based on research done over a decade ago using synthetic hormones. "The synthetics are, you know, chemically produced and they're not exactly the same as what your body produces," she added. Bosia and many other doctors now use individually compounded bio-identical hormones. "A bio-identical is taken from the yam plant and it's structured -- if you look at the hydrogens and the oxygens -- it's structured exactly like the estradiol and … Continue reading →

By Amanda Williams PUBLISHED: 13:41 EST, 25 June 2013 | UPDATED: 02:29 EST, 26 June 2013 35 shares 47 View comments Women taking hormone replacement therapy following the menopause are not at a higher risk of developing dementia, a study has claimed Women taking hormone replacement therapy following the menopause are not at a higher risk of developing dementia, a study has claimed. HRT, which is used to treat the symptoms of menopause, including hot flushes, has been previously linked with declining memory and a doubled risk of developing dementia. Researchers followed a group of more than 1,300 women between the ages of 50 and 55 who were on HRT medication called conjugated equine oestrogens (CEOs). The researchers, based at the Women's Health Centre of Excellence for Research at Wake Forest School of Medicine in Winston-Salem, North Carolina, gave one set of women placebos and one the HRT treatment, then studied the results after seven years. See the article here: HRT does NOT affect a woman's memory or increase her risk of developing dementia … Continue reading →

Editor's Choice Academic Journal Main Category: Menopause Also Included In: Women's Health / Gynecology Article Date: 26 Jun 2013 - 0:00 PDT Current ratings for: HRT Not Linked To Cognitive Problems In Women 50 To 55 The study showed that postmenopausal hormone therapy with conjugated equine estrogens (CEEs) is not linked to overall sustained benefit or risk to cognitive function in women of this age group. The therapy consists of a synthetic mixture of estrogen and is used to treat the symptoms of menopause, such as hot flashes and vaginal dryness. A previous report, the Women's Health Initiative Memory Study (WHIMS), found that women ages 65 and older taking postmenopausal hormone therapy with CEEs experienced deficits in global and domain-specific cognitive functioning. The authors explained that until now, it was not known whether the treatment had the same effect on younger women. Therefore, the new study, the Women's Health Initiative Memory Study of Younger Women (WHIMSY), analyzed whether younger postmenopausal women taking CEE-based hormone therapy resulted in longer-term influences on cognitive function. The team of experts, led by Mark A. Espeland, Ph.D., of the Wake Forest School of Medicine, Winston-Salem, N.C., presented the primary results from this investigation in JAMA … Continue reading →

Women taking hormone replacement therapy (HRT) following menopause won't suffer memory problems or declines in their cognitive abilities, according to a new study. Researchers tracked more than 1,300 women who had been given hormone medications called conjugated equine estrogens (CEEs). The treatment consists of a synthetic mixture of estrogen, or female sex hormones, and is used to treat symptoms of menopause, including hot flashes and vaginal dryness. Hormone replacement therapy may also help stave off bone loss for older women. But, previous research of women over 65 has linked the medication to cognitive deficits like memory loss and a two-fold risk increase for dementia. For the new study, researchers randomized postmenopausal women between the ages of 50 and 55 to either receiving hormone therapy or placebo. After seven years, the researchers followed up with the women, and determined no overall differences in cognitive function scores between women taking the CEEs and the placebos. The research suggests giving the hormones at an earlier age of menopause may be more beneficial than prescribing them later. "Our findings provide reassurance that CEE-based therapies when administered to women earlier in the postmenopausal period do not seem to convey long-term adverse consequences for cognitive function," … Continue reading →

(CBS News) For the past decade, women who are post-menopausal have been getting conflicting information about hormone replacement therapy. Now, a new study in the Journal of the American Medical Association is adding to the debate. The study of 1,326 women taking synthetic hormones over seven years found no risk to cognitive functions for women 50-55, and some cognitive decline for women 65 and older. Dr. Sue Decotiis, a hormone replacement specialist at the New York University Langone Medical Center, said the study used products that are old. She explained, "With this study, they were using conjugated equine estrogens, and what that means is they get that from the urine of a horse. ... They were started to be used in the 1940s, and I'm certainly no longer using them in my practice." She said she's "not really" a fan of this study because they used something other than natural human estrogen known as beta estradiol. "They're not using the right product," she said. "It's sort of using the wrong key to get in your apartment. You're not going to get in. You're not going to get the right answers. We have to use the hormones that our body relates … Continue reading →

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