Category Archives: Mesenchymal Stem Cells

An injection of a patient's bone marrow stem cells during rotator cuff surgery significantly improved healing and tendon durability, according to a study presented today at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). Each year in the U.S., more than 2 million people have rotator cuff surgery to re-attach their shoulder tendon to the head of the humerus (upper arm bone). Rotator cuff tears can occur during a fall or when lifting an extremely heavy object; however, most tears are the result of aging and overuse. The French study, of which a portion appeared in the September 2014 issue of International Orthopaedics, included 90 patients who underwent rotator cuff surgery. Researchers tried to make the two groups as equivalent as possible based on rotator cuff tear size, tendon rupture location, dominate shoulder, gender and age. Forty-five of the patients received injections of bone marrow concentrate (BMC) mesenchymal stem cells (MSCs) at the surgical site, and 45 had their rotator cuff repaired or reattached without MSCs. Patient ultrasound images were obtained each month following surgery for 24 months. In addition, MRI images were obtained of patient shoulders at three and six months following surgery, and at … Continue reading →

Celprogen Released Stem Cell Active Ingredients for the Cosmetic Industry Tested and Validated in Cosmetic Products for a Decade The present invention relates to culturing stem cells in animal free conditions has been developed and optimized by Celprogen utilizing single use bioreactor technology. The cosmetic industry has benefited from this technology for their regenerative skin care product lines. The topical application of these skin care products utilizing Celprogens Stem Cell Derived Conditioned Media have been in the market for 10 plus years. About Celprogen Inc. Celprogen Inc. is a global Stem Cell Research & Therapeutics company which is developing a proprietary portfolio of unique therapeutics products and life science research tools that includes genetic engineering technologies, stem cell technologies for regenerative medicine, as well as bio-engineering products for tissue & organ transplants. Headquartered in Torrance, California, Celprogen is committed to the research, development, and manufacture of quality Stem Cell, Cancer Stem Cell and Primary Cell Culture products to serve our global community. Additional information about Celprogen is available at http://www.celprogen.com. For additional information on the product line contact: Jay Sharma Phone: 310 542 8822 info@celprogen.com http://www.celprogen.com Read more here: Celprogen Released Stem Cell Active Ingredients for the Cosmetic Industry Tested … Continue reading →

LAS VEGAS, March 26, 2015 /PRNewswire-USNewswire/ -- An injection of a patient's bone marrow stem cells during rotator cuff surgery significantly improved healing and tendon durability, according to a study presented today at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). Each year in the U.S., more than 2 million people have rotator cuff surgery to re-attach their shoulder tendon to the head of the humerus (upper arm bone). Rotator cuff tears can occur during a fall or when lifting an extremely heavy object; however, most tears are the result of aging and overuse. The French study, of which a portion appeared in the September 2014 issue of International Orthopaedics, included 90 patients who underwent rotator cuff surgery. Researchers tried to make the two groups as equivalent as possible based on rotator cuff tear size, tendon rupture location, dominate shoulder, gender and age. Forty-five of the patients received injections of bone marrow concentrate (BMC) mesenchymal stem cells (MSCs) at the surgical site, and 45 had their rotator cuff repaired or reattached without MSCs. Patient ultrasound images were obtained each month following surgery for 24 months. In addition, MRI images were obtained of patient shoulders at three … Continue reading →

Contact Information Available for logged-in reporters only Newswise March 24, 2015, NATIONAL HARBOR, Md. - Mesenchymal stem cell (MSC) transplantation reduced opioid tolerance and opioid-induced hyperalgesia caused by daily morphine injections in rats, according to new research. The results could herald stem cell transplantation as an innovative, safe, efficacious and cost-effective therapy to treat pain and opioid tolerance, said researchers, who presented results in a Plenary Research Highlight session at the 31st Annual Meeting of the American Academy of Pain Medicine. Not only was opioid tolerance prevented when the rats were transplanted with MSC before repeated morphine injections, but tolerance was reversed when the rats were treated after opioid tolerance had developed, results demonstrated. MSCs have a remarkable anti-inflammatory effect and a powerful anti-tolerance effect, said the studys principal investigator, Jianguo Cheng, M.D., Ph.D., who led the research team from the Cleveland Clinic, in Ohio. Although clinical trials are still three to five years away, he said, eventually, The results may apply to millions of patients with a wide range of pain states, including cancer pain and other intractable chronic pain that requires long-term opioid therapy. Furthermore, Cheng characterized the procedure as practical, in light of readily available sources of … Continue reading →

Top Features Psychedelic Drug Use Could Reduce Psychological Distress, Suicidal Thinking A history of psychedelic drug use is associated with less psychological distress and fewer suicidal thoughts, planning, and attempts, according to new research from Johns Hopkins and the University of Alabama at Birmingham. Researchers at Johns Hopkins have successfully corrected a genetic error in stem cells from patients with sickle cell disease, then used those cells to grow mature red blood cells. When and why do physicians prescribe costlier brand-name drugs when generic ones are available? Thats the question the Food and Drug Administration has put to a Johns Hopkins team, which has been tapped to conduct a two-year study that will analyze factors that determine underuse of generic drugs. Even though the ORC protein machinery is crucial to life, we didnt know much about how it works, says James Berger, Ph.D. By learning what it looks like, down to the arrangement of each atom, we can get a sense of where it interacts with DNA and how it does its job. At noon on Friday, March 20, fourth-year medical students from the Johns Hopkins University School of Medicine and all across the country learned where they will begin … Continue reading →

stem cell therapy Jakarta tangerang serpong bsd bintaro http://youtu.be/E-XmebCWfKs. By: Layar Baru DKI … Continue reading →

Those hospitals and medical institutions advertising treatment of incurable diseases with stems cells are now under scanner of the Union Ministry of Health and Family Welfare. The ministry has already processed complaints against at least 23 website advertisements. The National Apex Committee for Stem Cell Research and Therapy (NACSCRT), under the Indian Council of Medical Research, has looped in Advertising Standards Council of India (ASCI) to monitor advertisements that claim to fully cure patients with stem cell based therapies. Several clinics and organisations advertise stem cell therapies whose safety and efficacy are not proven, to attract vulnerable patients. As per the National Guidelines for Stem Cell Research 2013, stem cell therapy has not been proven effective other than in Hematopoietic Stem Cell Transplantation (HSCT) for haematological disorders (disorders which primarily affect the blood). NAC-SCRT has observed that several clinicians, companies, hospitals advertise stem cell based therapies other than haematopoietic stem cell transplantation for haematological disorders on their websites. Officials clearly say that these therapies are currently investigational and must be conducted only within the scope of clinical trials. Dr. Alok Srivastava, Chairman, NAC-SCRT said, "Advertisements claiming to offer stem cell-based therapies other than Haematopoietic Stem Cell Transplantations for blood diseases … Continue reading →

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohns disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell populations phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing … Continue reading →

5 hours ago by Denis Paiste MIT biological engineering graduate student Frances Liu works with a spiral-shaped inertial microfluidic separation device for separating stem cell populations in the Laboratory for Material Chemomechanics at MIT. This device was adapted from previous designs to separate cells as a function of diameter. Liu also grows bone marrow-derived stem cells and studies how those stem cells release certain chemicals in response to mechanical interactions with materials in the surrounding environment. Credit: Denis Paiste/Materials Processing Center Researchers in MIT Associate Professor Krystyn J. Van Vliet's group last year showed that three biomechanical and biophysical markers could accurately identify the most desirable stem cells from a mixed group of bone marrow-derived cells. Now, MIT biological engineering graduate student Frances Liu is trying to advance that work by understanding how to alter the stem cells' physical environment to get them to produce the most desirable chemical output. The bone marrow cells secrete special chemicals called cytokines that are needed in the body to repair bone tissue, fat tissue, and connective tissue like cartilage. "These so-called factors that the cells produce are associated with those tissue growth functions and tissue repair functions," Van Vliet says. Liu grows bone … Continue reading →

stem cell medicine Jakarta tangerang serpong bsd bintaro http://youtu.be/e8ihj9O6b-4 http://youtu.be/kbpkTtpqBBw. By: Layar Baru DKI … Continue reading →