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Category Archives: Parkinson’s Treatment

Breakthrough by North-East researchers could lead to earlier diagnosis of Parkinson's

Posted: Published on January 15th, 2013

Breakthrough by North-East researchers could lead to earlier diagnosis of Parkinson's 1:00am Tuesday 15th January 2013 in News By Barry Nelson, Health Editor A NEW study by North-East researchers could help earlier diagnosis of Parkinson 's disease. While movement - motor - problems are the main symptom of Parkinson's, non-motor problems such as drooling, anxiety and bowel problems affect a large number of patients and begin sooner than previously thought. Earlier diagnosis could lead to earlier treatment and allow patients to have a better quality of life. In the study, published in the journal Neurology, the medical journal of the American Academy of Neurology, researchers from Newcastle University compared 159 people with newly-diagnosed Parkinson's disease to 99 people of similar ages who did not have the disease. Participants were asked whether they experienced any of the 30 non-motor symptoms screened for, including sexual problems, sleep problems and gastrointestinal problems. Study author Dr Tien K. Khoo said: "Often people don't even mention these symptoms to their doctors, and doctors don't ask about them, yet many times they can be treated effectively." The people with Parkinson's disease had an average of eight of the non-motor problems, compared to three non-motor symptoms for … Continue reading

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Parkinson's can lead to anxiety and other non-motor symptoms, even early on

Posted: Published on January 15th, 2013

Jan. 14, 2013 While movement problems are the main symptom of Parkinson's disease, a new study shows that even early in the course of disease people frequently experience many non-motor symptoms such as drooling, anxiety and constipation. The study is published in the January 15, 2013, print issue of Neurology, the medical journal of the American Academy of Neurology. "Oftentimes people with early Parkinson's don't even mention these symptoms to their doctors, and doctors don't ask about them, yet many times they can be treated effectively," said study author Tien K. Khoo, PhD, of Newcastle University in the United Kingdom. The study compared 159 people with newly diagnosed Parkinson's disease to 99 people of similar ages who did not have the condition. Participants were asked whether they experienced any of the 30 non-motor symptoms screened for, including sexual problems, sleep problems and gastrointestinal problems. Those with Parkinson's disease had an average of eight of the non-motor problems, compared to three for the people who did not have the disorder. Among the most common symptoms for those with Parkinson's disease were drooling, urinary urgency, constipation, anxiety and a reduced sense of smell. These likely represent other symptoms of Parkinson's that may … Continue reading

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Dopamine Therapy Instilling Improved Mobility, Creativeness In Parkinson's Patients

Posted: Published on January 14th, 2013

January 14, 2013 Lawrence LeBlond for redOrbit.com Your Universe Online Health experts around the world are talking about a remarkable phenomenon seen in Parkinsons patients that was first noticed by researchers at Tel Aviv Universitys Sackler Faculty of Medicine over the holidays. Professor Rivka Inzelberg said patients she treated at Sheba Medical Center clinic had skipped bringing the usual presents of chocolate, flowers and knick-knacks in over the holiday season and had instead brought in works of art that they had made themselves. The remarkableness of this has to do with a drug that has been administered to many of these patients to increase dopamine activity in the brain as a therapy for loss of motor skills that come with tremors and muscle rigidity. Inspired by the discovery, Inzelberg further sought out evidence elsewhere to ensure it wasnt a fluke seen only in her practice. By researching other case studies around the world, Inzelberg analyzed the data to come to the conclusion that all of the patients she encountered had been treated with either synthetic precursors of dopamine or dopamine receptor agonists. Publishing her findings in the journal Behavioral Neuroscience, Inzelberg said dopamines main purpose is to aid in the … Continue reading

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New Parkinson's Disease Exercise Program Alleviates Patient Suffering

Posted: Published on January 14th, 2013

Experienced fitness PD practitioners, David Zid & Jackie Russell, deliver evidence-based follow-up to #1-selling book detailing Parkinson's defeating exercise program, Delay the Disease . Columbus, OH (PRWEB) January 14, 2013 For most of us, being able to pass through an open doorway, get out of a car, dressing, or simply walking in a crowd is something we take for granted. However, for people with Parkinsons disease, being able to perform ADL's such as these can be a struggle. This program clearly demonstrates tips for accomplishing daily tasks with corresponding exercises to help conquer everyday challenges of living with this disease. The latest research is showing promise that exercise has the ability to not only slow the progression of the disease but perhaps even reverse it. What the professionals are saying about Delay the Disease : "The last major breakthrough in our understanding of treating and altering the course of Parkinson's comes in the form of dedicated exercise routinesprograms like Delay the Disease demonstrate significant, and in some cases, breathtaking reversal of disability" -- Lawrence W. Elmer, MD, Ph.D. Professor of Neurology, Director -- The Center for Neurological Health, Director -- Parkinson's Disease and Movement Disorders Program, University of Toledo "One … Continue reading

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Parkinson's treatment can trigger creativity

Posted: Published on January 14th, 2013

Public release date: 14-Jan-2013 [ | E-mail | Share ] Contact: George Hunka ghunka@aftau.org 212-742-9070 American Friends of Tel Aviv University Parkinson's experts across the world have been reporting a remarkable phenomenon many patients treated with drugs to increase the activity of dopamine in the brain as a therapy for motor symptoms such as tremors and muscle rigidity are developing new creative talents, including painting, sculpting, writing, and more. Prof. Rivka Inzelberg of Tel Aviv University's Sackler Faculty of Medicine first noticed the trend in her own Sheba Medical Center clinic when the usual holiday presents from patients typically chocolates or similar gifts took a surprising turn. "Instead, patients starting bringing us art they had made themselves," she says. Inspired by the discovery, Prof. Inzelberg sought out evidence of this rise in creativity in current medical literature. Bringing together case studies from around the world, she examined the details of each patient to uncover a common underlying factor all were being treated with either synthetic precursors of dopamine or dopamine receptor agonists, which increase the amount of dopamine activity in the brain by stimulating receptors. Her report will be published in the journal Behavioral Neuroscience. Giving in to artistic impulse … Continue reading

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Parkinson's treatment can trigger creativity: Patients treated with dopamine-enhancing drugs are developing artistic …

Posted: Published on January 14th, 2013

Jan. 14, 2013 Parkinson's experts across the world have been reporting a remarkable phenomenon -- many patients treated with drugs to increase the activity of dopamine in the brain as a therapy for motor symptoms such as tremors and muscle rigidity are developing new creative talents, including painting, sculpting, writing, and more. Prof. Rivka Inzelberg of Tel Aviv University's Sackler Faculty of Medicine first noticed the trend in her own Sheba Medical Center clinic when the usual holiday presents from patients -- typically chocolates or similar gifts -- took a surprising turn. "Instead, patients starting bringing us art they had made themselves," she says. Inspired by the discovery, Prof. Inzelberg sought out evidence of this rise in creativity in current medical literature. Bringing together case studies from around the world, she examined the details of each patient to uncover a common underlying factor -- all were being treated with either synthetic precursors of dopamine or dopamine receptor agonists, which increase the amount of dopamine activity in the brain by stimulating receptors. Her report will be published in the journal Behavioral Neuroscience. Giving in to artistic impulse Dopamine is involved in several neurological systems, explains Prof. Inzelberg. Its main purpose is … Continue reading

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First test to detect Parkinson's disease developed by studying tissue taken from under the jaw

Posted: Published on January 12th, 2013

Doctors say tissue sample taken from the saliva glands could reveal abnormal protein, which is tell-tale sign But charity warns the study was small and too invasive to become a routine test By Anna Hodgekiss PUBLISHED: 12:06 EST, 11 January 2013 | UPDATED: 12:14 EST, 11 January 2013 Former boxer Muhammad Ali is one of world's best-known people to suffer from Parkinson's disease, for which is there is no diagnostic test Scientists have developed the first diagnostic test to detect Parkinson's disease. The new test is based on taking a tissue sample from the saliva glands found under the lower jaw. Currently, there are no tools to detect the devastating condition that mainly affects people aged over fifty. Instead doctors base a diagnosis on common symptoms, which include slowness, stiffness of muscles and tremors. Described as a 'big step forward' for treatment, scientists now suggest a portion of a person's saliva gland can show up the illness. Dr Charles Adler, a neurologist at the Mayo Clinic, Arizona, said: 'There is currently no diagnostic test for Parkinson's disease. See original here: First test to detect Parkinson's disease developed by studying tissue taken from under the jaw … Continue reading

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Scientists uncover potential drug target to block cell death in Parkinson's disease

Posted: Published on January 10th, 2013

Jan. 10, 2013 Oxidative stress is a primary villain in a host of diseases that range from cancer and heart failure to Alzheimer's disease, Amyotrophic Lateral Sclerosis and Parkinson's disease. Now, scientists from the Florida campus of The Scripps Research Institute (TSRI) have found that blocking the interaction of a critical enzyme may counteract the destruction of neurons associated with these neurodegenerative diseases, suggesting a potential new target for drug development. These findings appear in the January 11, 2013 edition of The Journal of Biological Chemistry. During periods of cellular stress, such as exposure to UV radiation, the number of highly reactive oxygen-containing molecules can increase in cells, resulting in serious damage. However, relatively little is known about the role played in this process by a number of stress-related enzymes. In the new study, the TSRI team led by Professor Philip LoGrasso focused on an enzyme known as c-jun-N-terminal kinase (JNK). Under stress, JNK migrates to the mitochondria, the part of the cell that generates chemical energy and is involved in cell growth and death. That migration, coupled with JNK activation, is associated with a number of serious health issues, including mitochondrial dysfunction, which has long been known to contribute … Continue reading

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Saliva gland test for Parkinson's disease?

Posted: Published on January 10th, 2013

Jan. 10, 2013 New research suggests that testing a portion of a person's saliva gland may be a way to diagnose Parkinson's disease. The study was released January 10 and will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013. "There is currently no diagnostic test for Parkinson's disease," said study author Charles Adler, MD, PhD, with the Mayo Clinic Arizona and a Fellow of the American Academy of Neurology. "We have previously shown in autopsies of Parkinson's patients that the abnormal proteins associated with Parkinson's are consistently found in the submandibular salivary glands, under the lower jaw, and this is the first study demonstrating the value of testing a portion of the saliva gland to diagnose a living person for Parkinson's disease. Making a diagnosis in living patients is a big step forward in our effort to understand and better treat patients." The study involved 15 people with an average age of 68 who had Parkinson's disease for an average of 12 years, responded to Parkinson's medication and did not have known salivary gland disorders. Biopsies were taken of two different salivary glands: the gland under the lower jaw … Continue reading

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Saliva gland test for Parkinson's shows promise, study finds

Posted: Published on January 10th, 2013

Public release date: 10-Jan-2013 [ | E-mail | Share ] Contact: Jim Mcveigh mcveigh.jim@mayo.edu 480-301-4368 Mayo Clinic PHOENIX Described as a "big step forward" for research and treatment of Parkinson's disease, new research from Mayo Clinic in Arizona and Banner Sun Health Research Institute suggests that testing a portion of a person's saliva gland may be a way to diagnose the disease. The study was released today and will be presented at the American Academy of Neurology's annual meeting in San Diego in March. "There is currently no diagnostic test for Parkinson's disease," says study author Charles Adler, M.D., Ph.D., a neurologist with Mayo Clinic in Arizona. "We have previously shown in autopsies of Parkinson's patients that the abnormal proteins associated with Parkinson's are consistently found in the submandibular saliva glands, found under the lower jaw. This is the first study demonstrating the value of testing a portion of the saliva gland to diagnose a living person with Parkinson's disease. Making a diagnosis in living patients is a big step forward in our effort to understand and better treat patients." The study involved 15 people with an average age of 68 who had Parkinson's disease for an average of 12 … Continue reading

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