Category Archives: Parkinson’s Treatment

The most critical problem in the treatment of neurodegenerative diseases is brain neuronal protection, which can be overcome by clearing pathological substances and regulating the immune environment. In the above treatment strategies, the traditional poor drug delivery problem is inevitable. Here, we show an engineering core-shell hybrid system named rabies virus glycoprotein (RVG) peptidemodified exosome (EXO) curcumin/phenylboronic acid-poly(2-(dimethylamino)ethyl acrylate) nanoparticle/small interfering RNA targeting SNCA (REXO-C/ANP/S) Continue reading →

Rare Brain Diseases Linked to COVID-19 Fuel Demand for Neural Implants As the number of COVID-19 (coronavirus) cases continue to rise in the U.S., Russia, France, and Brazil, life-threatening and rare brain diseases are being linked to the infection. This has brought companies in the brain implants market into picture, since their assistance is crucial in the already stressed healthcare facilities. It has been found that certain individuals in their late 50s are at a risk of developing acute necrotizing encephalitis, which is a rare complication of influenza and other viral infections. Continue reading →

Anosmia is the inability or decreased ability to smell. It can be permanent or temporary, depending on the cause Continue reading →

NEW YORK, Dec. Continue reading →

RESULTS Histone H3K4me3 and its catalyzing enzymes are significantly elevated in PFC of patients with AD and mutant Tau transgenic mice To elucidate the role of histone methylation in AD, we examined the alterations of histone methylation marks associated with gene activation or silencing in the postmortem PFC (Brodmanns area 10) tissues from patients with AD (five to six Braak stages). Compared with age- or sex-matched control subjects, the level of permissive H3K4me3 in the nuclear fraction of PFC lysates from patients with AD was significantly increased [Fig. 1A; Ctrl: n = 9, AD: n = 11, t(18) = 5.4, P < 0.001; t test], while no significant changes were found on the level of repressive H3K27me3 or enhancer H3K4me Continue reading →

BELLEAIR The Town Commission may install a temporary replacement for Mayor Gary H. Continue reading →

December 08, 2020 07:00 ET | Source: Cerevel Therapeutics CAMBRIDGE, Mass., Dec. 08, 2020 (GLOBE NEWSWIRE) -- Cerevel Therapeutics (Nasdaq: CERE), a company dedicated to unraveling the mysteries of the brain totreatneurosciencediseases, announced today that it has added Ruth McKernan, Ph.D., CBE, FMedSci, to serve as an independent member of its Board of Directors. Dr. Continue reading →

December 09, 2020 08:00 ET | Source: Prothena Corporation plc DUBLIN, Ireland, Dec. Continue reading →

SALT LAKE CITY, Dec. 10, 2020 (GLOBE NEWSWIRE) -- Clene Nanomedicine, Inc., a clinical-stage biopharmaceutical company, today announced the presentation of blinded interim results from the Phase 2 RESCUE-ALS clinical trial investigating the effects of its lead clinical candidate, CNM-Au8, for the treatment of amyotrophic lateral sclerosis (ALS). CNM-Au8 is an aqueous suspension of clean-surfaced, faceted gold nanocrystals with catalytic activity that has been shown to enhance the metabolic energetic capacity of motor neurons while simultaneouslyreducing oxidative stress Continue reading →

An eye exam may be all that is needed to diagnose Parkinson's disease, new research shows. Using an advanced machine-learning algorithm and fundus eye images, which depict the small blood vessels and more at the back of the eye, investigators are able to classify patients with Parkinson's disease compared against a control group. Continue reading →