Iranian researcher discovers factor of stem cell disorder

Source: ISNA, Tehran

The researches have studied mesenchymal stem cells or MSCs derived from mice bone marrow in cell culture period and succeeded to identify new division in cell latency period which can lead to chromosomal disorders in the cells.

Phd student in Hematology at Tarbiat Modarres University in Tehran, Naser Ahmad Beigi told ISNA that mesenchymal stem cells are powerful tools in cell therapeutic and tissue engineering because of their special specifications. For the same reasons stem cells derived from them are used effectively in experiments.

He added during the procedure of separating mesenchymal stem cells from mice bone marrows, many researchers believe them to be dead and refuse to continue the procedure and this is because of changing form of the cells and a reduction in their propagation at the beginning level of the cell culture.

Beigi stressed these signs show latency period and that cells would be propagated without showing any signs for a long time if the culture continues. He noted an unknown division is the specification of the latency period which leads to chromosomal disorders.

He added the disorders can lead to the appearance of tumors inside the body and inefficiency of non-carcinogenic drugs and restraining mitosis is the only mechanism to prevent them.

"Identifying the mechanism of the new division can lead to producing new generation of non-carcinogenic medicines with high efficiency in the near future, "Beigi added.

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Iranian researcher discovers factor of stem cell disorder