NASA Spaceline Current Awareness List #623 7 November 2014

Papers deriving from NASA support: 1 Clment G, Wood SJ. Rocking or rolling - Perception of ambiguous motion after returning from space. PLoS One. 2014 Oct 29;9(10):e111107. http://www.ncbi.nlm.nih.gov/pubmed/25354042 (PI: S.J. Wood) Note:Motion tests were conducted on eleven astronauts before and after two-week flights on board the Space Shuttle. This article may be obtained online without charge. Journal Impact Factor:3.524 Funding:This research was supported by the National Aeronautics and Space Administration Human Research Program Human Health Countermeasures Element (SW), the European Space Agency (GC), and the Centre National dEtudes Spatiales (GC). 2 Linnarsson D, Hughson RL, Fraser KS, Clment G, Karlsson LL, Mulder E, Paloski WH, Rittweger J, Wuyts FL, Zange J. Effects of an artificial gravity countermeasure on orthostatic tolerance, blood volumes and aerobic power after short-term bed rest (BR-AG1). J Appl Physiol (1985). 2014 Oct 23:jap.00061.2014. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/25342708 Note:Bed rest study. Centrifugation was used as artificial gravity. Journal Impact Factor:3.434 Funding:This study was funded by the European Space Agency, and was performed at MEDES, Toulouse, FranceIn addition the authors have been supported by their respective research organisations. W.H. Paloski is at NASA Johnson Space Center. 3 Blue RS, Mathers CH, Castleberry Tl, Vanderploeg JM. The human challenges of commercial spaceflight: An overview of medical research conducted by the University of Texas Medical Branch through the Federal Aviation Administration Center of Excellence for Commercial Space Transportation. New Space. 2014 Sep;2(3):124-30. http://online.liebertpub.com/doi/abs/10.1089/space.2014.0012 (PI: J.M. Vanderploeg) Journal Impact Factor:Not available for this journal. Funding:The authors acknowledge the contributions of the FAA, the NASTAR facility and staff under the FAA COE CST, and the National Space Biomedical Research Institute (NSBRI) through NASA NCC 9-58. 4 Kantara C, O'Connell MR, Luthra G, Gajjar A, Sarkar S, Ullrich RL, Singh P. Methods for detecting circulating cancer stem cells (CCSCs) as a novel approach for diagnosis of colon cancer relapse/metastasis. Lab Invest. 2014 Oct 27. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/25347154 (PI: R.L. Ullrich/NSCOR) Journal Impact Factor:3.828 Funding:This work was supported by NIH grants CA97959 and CA114264 to PS and NASA grants NNX09AM08G and NNJ04HD83G to RU. 5 Norbury JW, Slaba TC. Space radiation accelerator experiments The role of neutrons and light ions. Life Sci Space Res. 2014 Oct 28. [Article in Press] http://www.sciencedirect.com/science/article/pii/S2214552414000534 (PI: J.W. Norbury) Journal Impact Factor:1.183 Funding:This work was supported by the Human Research Program under the Human Exploration and Operations Mission Directorate of NASA. 6 Kolev OI, Reschke MF. Internally versus externally mediated triggers in the acquisition of visual targets in the horizontal plane. Behav Brain Res. 2014 Jun 1;266:131-6. Epub 2014 Mar 12. http://www.ncbi.nlm.nih.gov/pubmed/24613978 (PI: M.F. Reschke) Journal Impact Factor:3.391 Funding:No funding acknowledged. M.F. Reschke is at NASA Johnson Space Center. 7 Meredith FL, Rennie KJ. Zonal variations in K+ currents in vestibular crista calyx terminals. J Neurophysiol. 2014 Oct 15:jn.00399.2014. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/25343781 (PI: F.L. Meredith, NSBRI Postdoctoral Fellowship Program) Journal Impact Factor:3.041 Funding:This work was supported by the National Space Biomedical Research Institute through NCC 9-58 to FLM and an American Hearing Research Foundation Grant to KJR. 8 Zheng J, Han SW, Rodriguez-Welsh MF, Rojas-Pierce M. Homotypic vacuole fusion requires VTI11 and is regulated by phosphoinositides. Mol Plant. 2014 Jun;7(6):1026-40. Epub 2014 Feb 25. http://www.ncbi.nlm.nih.gov/pubmed/24569132 (PI: M. Rojas-Pierce) Journal Impact Factor:6.605 Funding:This work was supported by National Science Foundation grant MCB-1244354, NASA grant NNX13AM49G to M.R.P., and start-up funds from North Carolina State University and the North Carolina Agricultural Research Service. __________________________________________________________________________ Other papers of interest: 1 Larina IM, Ivanisenko VA, Nikolaev EN, Grigorev AI. The proteome of a healthy human during physical activity under extreme conditions. Acta Naturae. 2014 Jul;6(3):66-75. Review. http://www.ncbi.nlm.nih.gov/pubmed/25349715 Note:This article may be obtained online without charge. 2 Mahon RT, Cronin WA, Bodo M, Tirumala S, Regis DP, Auker CR. Cardiovascular parameters in a mixed gender swine study of severe decompression sickness treated with the emulsified perfluorocarbon Oxycyte. J Appl Physiol (1985). 2014 Oct 23:jap.00727.2014. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/25342702 3 Powers SK. Can antioxidants protect against disuse muscle atrophy? Sports Med. 2014 Nov;44 Suppl 2:155-65. Review. http://www.ncbi.nlm.nih.gov/pubmed/25355189 Note:This article may be obtained online without charge. 4 Shen H, Grimston S, Civitelli R, Thomopoulos S. Deletion of connexin43 in osteoblasts/osteocytes leads to impaired muscle formation in mice. J Bone Miner Res. 2014 Oct 27. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/25348938 5 Pajevic PD, Spatz JM, Garr J, Adamson C, Misener L. Osteocyte biology and space flight. Curr Biotechnol. 2013;2(3):179-183. http://www.ncbi.nlm.nih.gov/pubmed/25346885 Note:Discusses osteocyte research done on Bion-11; the OSTEO hardware used on STS, FOTON, and ISS; and the Bioculture Systems slated for ISS. This article may be obtained online without charge. 6 Steward AJ, Kelly DJ, Wagner DR. The role of calcium signalling in the chondrogenic response of mesenchymal stem cells to hydrostatic pressure. Eur Cell Mater. 2014 Oct 28;28:358-71. http://www.ncbi.nlm.nih.gov/pubmed/25350251 Note:This article may be obtained online without charge. 7 Fazelipour S, Kiaei SB, Tootian Z, Haeri SA, Zehtabvar O, Sadeghinezhad J. Cimetidine administration decreases radiogenic damage on the thyroid gland in mice. Int J Radiat Biol. 2014 Oct 27:1-21. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/25347146 8 Hammam E, Bolton PS, Kwok K, Macefield VG. Vestibular modulation of muscle sympathetic nerve activity during sinusoidal linear acceleration in supine humans. Front Neurosci. 2014 Oct 9;8:316. http://www.ncbi.nlm.nih.gov/pubmed/25346657 Note:This article may be obtained online without charge. 9 Rejc E, di Prampero PE, Lazzer S, Grassi B, Simunic B, Pisot R, Antonutto G, Narici M. Maximal explosive power of the lower limbs before and after 35days of bed rest under different diet energy intake. Eur J Appl Physiol. 2014 Oct 26. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/25344798 Note:Bed rest study. 10 Jaroensanti N, Yoon JM, Nakai Y, Shirai I, Otani M, Par
k SH, Hayashi K, Nakajima M, Asami T. Does the brassinosteroid signal pathway in photomorphogenesis overlap with the gravitropic response caused by auxin? Biosci Biotechnol Biochem. 2014 Nov;78(11):1839-49. Epub 2014 Jun 26. http://www.ncbi.nlm.nih.gov/pubmed/25351332 11 Iskratsch T, Wolfenson H, Sheetz MP. Appreciating force and shape - The rise of mechanotransduction in cell biology. Nat Rev Mol Cell Biol. 2014 Oct 30. [Epub ahead of print] Review. http://www.ncbi.nlm.nih.gov/pubmed/25355507 12 Humphrey JD, Dufresne ER, Schwartz MA. Mechanotransduction and extracellular matrix homeostasis. Nat Rev Mol Cell Biol. 2014 Oct 22. [Epub ahead of print] Review. http://www.ncbi.nlm.nih.gov/pubmed/25355505 13 Zhang Y, Ge C, Zhu C, Salaita K. DNA-based digital tension probes reveal integrin forces during early cell adhesion. Nat Commun. 2014 Oct 24;5:5167. http://www.ncbi.nlm.nih.gov/pubmed/25342432 14 Mendes CS, Rajendren SV, Bartos I, Mrka S, Mann RS. Kinematic responses to changes in walking orientation and gravitational load inDrosophila melanogaster. PLoS One. 2014 Oct 28;9(10):e109204. http://www.ncbi.nlm.nih.gov/pubmed/25350743 Note:Gravitational load was added by gluing spherical ball bearings with different densities to the notum of the flies. Weights corresponded to 0.66, 1.14, and 2.02 times an average body mass. This article may be obtained online without charge.

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NASA Spaceline Current Awareness List #623 7 November 2014