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Category Archives: Cell Therapy

NeoStem Announces Proposed Public Offering of Common Stock and Warrants

Posted: Published on March 29th, 2012

NEW YORK, March 28, 2012 (GLOBE NEWSWIRE) -- NeoStem, Inc. (NYSE Amex:NBS) ("NeoStem" or "the Company"), a leader in the cell therapy industry, today announced that it intends to offer and sell shares of its common stock and warrants in an underwritten public offering. All of the shares and warrants in the offering will be sold by NeoStem. The offering is subject to market conditions, and there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering. The securities will be issued pursuant to a prospectus supplement filed as part of an effective registration statement on Form S-3 previously filed with the Securities and Exchange Commission (SEC). Maxim Group LLC is acting as book-runner of the offering. A shelf registration statement relating to the securities was filed with the SEC, which became effective on June 13, 2011. A preliminary prospectus supplement related to the offering will be filed with the SEC and will be available on the SEC's website at http://www.sec.gov. Copies of the preliminary prospectus supplement and the accompanying prospectus relating to this offering may be obtained, when available, from Maxim Group LLC, 405 … Continue reading

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Stem cell therapy for 13-year-old dog helps with its arthritis

Posted: Published on March 28th, 2012

COLUMBIA, SC (WIS) - A few weeks ago, we told you the story of Maggie, the 13-year-old Boykin Spaniel who was suffering from arthritis. Maggie is enjoying life once again thanks to a new type of surgery. The dog received stem cell therapy surgery six weeks ago. Doctors were able to use adult stem cells from Maggie's blood and fat samples to collect repair cells. They then took the cells and repaired the dog's arthritic spine. Maggie's owner, Beth Phibbs, says she could tell the dog had been in pain. "You could tell she didn't feel well, but yet now she is like she's 5 and she's 13. She just runs out and she plays. I think she knows. She can feel the difference," Phibbs said. The surgery costs about $2,000, but Medi-vet America says this costs about half as much as the older treatments. Previous Story: Copyright 2012 WIS. All rights reserved. Read more: Stem cell therapy for 13-year-old dog helps with its arthritis … Continue reading

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New gene therapy approach developed for red blood cell disorders

Posted: Published on March 28th, 2012

ScienceDaily (Mar. 27, 2012) A team of researchers led by scientists at Weill Cornell Medical College has designed what appears to be a powerful gene therapy strategy that can treat both beta-thalassemia disease and sickle cell anemia. They have also developed a test to predict patient response before treatment. This study's findings, published in PLoS ONE, represents a new approach to treating these related, and serious, red blood cells disorders, say the investigators. "This gene therapy technique has the potential to cure many patients, especially if we prescreen them to predict their response using just a few of their cells in a test tube," says the study's lead investigator, Dr. Stefano Rivella, Ph.D., an associate professor of genetic medicine at Weill Cornell Medical College. He led a team of 17 researchers in three countries. Dr. Rivella says this is the first time investigators have been able to correlate the outcome of transferring a healthy beta-globin gene into diseased cells with increased production of normal hemoglobin -- which has long been a barrier to effective treatment of these disease. So far, only one patient in France has been treated with gene therapy for beta thalassemia, and Dr. Rivella and his colleagues … Continue reading

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Cell therapy to improve quality of life – Video

Posted: Published on March 27th, 2012

25-03-2012 17:39 Dr Timothy Henry is Director of research at the Minneapolis Heart Institute Foundation and an Interventional cardiologist at the Minneapolis Heart Institute/ Abbott Northwestern Hospital. The interview was conducted on 24 March 2012 at the American College of Cardiology's (ACC's) 61st Annual Scientific Session & Expo in Chicago. See more ACC.12 Coverage: http://www.getinsidehealth.com More: Cell therapy to improve quality of life - Video … Continue reading

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Cell Therapy Improves Damaged Heart In Study

Posted: Published on March 27th, 2012

March 27, 2012 According to a new study, using a patients own bone marrow may help repair damaged areas of the heart caused by heart failure. Researchers found that left ventricular ejection fraction increased by 2.7 percent in patients who received stem cell therapy. The study, which was presented at the American College of Cardiologys 61st Annual Scientific Session, revealed that the improvement in ejection fraction correlated with the number of CD34+ and CD133+ cells in the bone marrow. This is the kind of information we need in order to move forward with the clinical use of stem cell therapy, Emerson Perin, MD, PhD, director of clinical research for cardiovascular medicine at the Texas Heart Institute and the studys lead investigator, said at the event. The study included 92 patients who were randomly selected to receive stem cell treatment or placebo. The patients all had chronic ischemic heart disease and an ejection fraction of less than 45 percent along with heart failure. Doctors placed a catheter in the hearts left ventricle to inject 3 ccs, or 100 million stem cells, into an average of 15 sites of the stem cell patients hearts. The doctors used electromechanical mapping of the heart … Continue reading

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Midlands Vet Uses Stem Cell Therapy for Pets in Pain

Posted: Published on March 27th, 2012

Columbia, SC (WLTX) --What if your pet couldn't walk anymore? One Midlands vet is using stem cell therapy to help. For Beth Phibbs it's almost like a turning back of the hands of time. "I call her my little miracle dog, because she's doing things she used to do," said Phibbs. "Now she's not on any medication, and she can go up and down the steps and she runs and jumps and things that she used to do when she was five." Phibbs has spent the last 13 years loving and looking after her pet dog Maggie, and when she pet began to develop arthritis and a limp she had to take action. But when the first treatments stopped working, Phibbs and Maggie had to look to another options, dog stem cell therapy. "I had no idea that animals were able to have they type of procedures," she said. Dr. Kenneth Banks a veterinarian with the Bank Animal Hospital, performed the surgery for Maggie using her own stem cells in the one day procedure. Banks said the stem cell therapy not only cost less than some other options, but was less invasive and had a quicker recovery time as well. … Continue reading

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Stem cell therapy possibly helpful in heart failure patients

Posted: Published on March 27th, 2012

Public release date: 24-Mar-2012 [ | E-mail | Share ] Contact: Beth Casteel bcasteel@acc.org 240-328-4549 American College of Cardiology CHICAGO -- A new study found that using a patient's own bone marrow cells may help repair damaged areas of the heart caused by heart failure, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session. The Scientific Session, the premier cardiovascular medical meeting, brings cardiovascular professionals together to further advances in the field. Millions of Americans suffer from heart failure, the weakening of the heart muscle and its inability to pump blood effectively throughout the body. If medications, surgery, or stents fail to control the disease, doctors often have few treatment options to offer. This is the largest study to date to look at stem cell therapy, using a patient's own stem cells, to repair damaged areas of the heart in patients with chronic ischemic heart disease and left ventricular dysfunction. Researchers found that left ventricular ejection fraction (the percentage of blood leaving the heart's main pumping chamber) increased by a small but significant amount (2.7 percent) in patients who received stem cell therapy. The study also revealed that the improvement in ejection fraction correlated … Continue reading

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Nuvilex Announces Advance in Gene Therapy for Encapsulated Living Cells Using Magnetic Nanoparticles

Posted: Published on March 27th, 2012

SILVER SPRING, Md.--(BUSINESS WIRE)-- Nuvilex, Inc. (OTCQB:NVLX), an emerging international biotechnology provider of cell and gene therapy solutions through its associate SG Austria, announced today a significant advance in gene therapy with a new, unique, and specialized system for induction of gene expression in encapsulated cells. In a recent publication in the Journal of Controlled Release, SG Austria and its research partners described a new system for induction of gene expression, or the means for stimulating a gene to be expressed within cells, including those that have been encapsulated and implanted in the body. The process described in the publication involves the stimulation of pre-programmed living cells, encapsulated using the Cell-in-a-Box technology, to express therapeutic genes under the control of a heat shock protein inducible promoter. This is done by simultaneously co-encapsulating pre-programmed cells and magnetic nanoparticles, which are much smaller than the cells. When subjected to an alternating magnetic field, the magnetic nanoparticles inside the capsules vibrate, producing heat. This results in a localized, temporary increase in temperature inside the capsules. This heat causes specialized heat shock proteins in the cells to induce expression of the therapeutic gene(s). Although both cell and gene therapies have an enormous range of … Continue reading

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bone marrow aspiration for stem cell therapy by Dr Adelson – Video

Posted: Published on March 26th, 2012

25-03-2012 10:22 Dr Adelson aspirates bone marrow for concentration for stem cell therapy for musculoskeletal pain conditions Original post: bone marrow aspiration for stem cell therapy by Dr Adelson - Video … Continue reading

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Adipose harvest for stem cell therapy by Dr Adelson – Video

Posted: Published on March 25th, 2012

24-03-2012 07:46 This is the harvest of adipose tissue for combination with bone marrow aspirate concentrate for stem cell therapy Originally posted here: Adipose harvest for stem cell therapy by Dr Adelson - Video … Continue reading

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