Category Archives: Testosterone

This article is about testosterone as a medication. For the natural hormone, see Testosterone.TestosteroneClinical dataPronunciation teh-STOS-t-rohn[1] Trade namesAndroGel, Testim, TestoGel, othersSynonymsAndrost-4-en-17-ol-3-oneAHFS/Drugs.comMonographMedlinePlusa614041License dataPregnancycategoryRoutes ofadministrationTransdermal (gel, cream, solution, patch), by mouth (as testosterone undecanoate), in the cheek, intranasal (gel), intramuscular injection (as esters), subcutaneous pelletsDrug classAndrogen, anabolic steroidATC codeLegal statusLegal statusPharmacokinetic dataBioavailabilityOral: very low (due to extensive first pass metabolism)Protein binding97.099.5% (to SHBG and albumin)[2]MetabolismLiver (mainly reduction and conjugation)Elimination half-life24hours[citation needed]ExcretionUrine (90%), feces (6%)Identifiers O=C4C=C2/[C@]([C@H]1CC[C@@]3([C@@H](O)CC[C@H]3[C@@H]1CC2)C)(C)CC4 Testosterone is a medication and naturally occurring steroid hormone.[3] It is used to treat male hypogonadism and certain types of breast cancer.[3] It may also be used to increase athletic ability in the form of doping.[3] It is unclear if the use of testosterone for low levels due to aging is beneficial or harmful.[4] Testosterone can be used as a gel or patch that is applied to the skin, injection into a muscle, tablet that is placed in the cheek, or tablet that is taken by mouth.[3] Common side effects of testosterone include acne, swelling, and breast enlargement in men.[3] Serious side effects may include liver toxicity, heart disease, and behavioral changes.[3] Women and children who are exposed may develop masculinization.[3] It is recommended that individuals with prostate cancer not use the medication.[3] It can cause harm to the baby if used during pregnancy or breastfeeding.[3] Testosterone is in the androgen family of medications.[3] Testosterone was first isolated in 1935.[5] Rates of use have increased three times in the United States between 2001 and 2011.[6] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[7] It is available as a generic medication.[3] The price depends on the dose and form of the product.[8] The primary use of testosterone is the treatment of males with too little or no natural testosterone production, also termed hypogonadism or hypoandrogenism (androgen deficiency).[9] This treatment is referred to as hormone replacement therapy (HRT), or alternatively, and more specifically, as testosterone replacement therapy (TRT) or androgen replacement therapy (ART) Continue reading →

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The two major testosterone gel brands are Testim and Androgel. They are very similar and generally prescribed interchangeably, but sometimes insurance wont cover one or the other Continue reading →

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Twenty Weeks on Testosterone I finally got to the clinic! inkgnosis.tumblr.com. By: gnomadink … Continue reading →

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