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Category Archives: Ulcerative Colitis

25000 people to benefit after NICE recommends new ulcerative colitis treatment – NICE

Posted: Published on March 15th, 2024

Thousands of people could be set to benefit after NICE today (Monday, 11 March) recommended a new one-a-day pill as an option for treating severe ulcerative colitis. NICEs final guidance on etrasimod (also known as Velsipity and made by Pfizer) is being published on the same day that the treatment was granted a licence by the Medicines and Healthcare Products Regulatory Agency (MHRA). Just over 25,000 people in England are eligible to receive the new treatment, which was evaluated using a simpler technology appraisal process. Continue reading

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NICE recommends new ulcerative colitis treatment for NHS use – Nursing Times

Posted: Published on March 15th, 2024

A new once-a-day pill has been recommended as an option for treating severe ulcerative colitis in England, with thousands of patients set to be eligible. The National Institute for Health and Care Excellence (NICE) has published final guidance backing the treatment etrasimod (Velsipity) We are determined to continue getting the best care to patients fast Helen Knight The move, on Monday, came on the same day that etrasimod was granted a licence by the Medicines and Healthcare Products Regulatory Agency (MHRA). Continue reading

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EU Commission Okays Pfizer’s VELSIPITY for Severe Ulcerative Colitis – Mirage News

Posted: Published on March 15th, 2024

Pfizer Inc. Continue reading

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Etrasimod positive opinion for ulcerative colitis upgraded to approval in EU – Hospital Healthcare

Posted: Published on February 28th, 2024

Etrasimod (brand name Velsipity) has been granted marketing authorisation by the European Commission (EC) for use in eligible patients with ulcerative colitis (UC), its manufacturer Pfizer has announced. It is approved to treat patients aged 16 years and older with moderately to severely active UC who have had an inadequate response, lost response, or were intolerant to either conventional therapy or a biological agent. Continue reading

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Prolonged culturing of colonic epithelial organoids derived from healthy individuals and ulcerative colitis patients … – Nature.com

Posted: Published on February 28th, 2024

Patient cohort description and pathology classification The present study was approved by the Kaunas Regional Biomedical Research Ethics Committee (Protocol No. BE-2-31) and written informed consent was obtained from each subject who participated in the study. All research was performed in accordance with relevant guidelines and regulations.This study consisted of three age- and sex-matched groups (Fig.4) Continue reading

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Will smart tech revolutionise drug delivery for ulcerative colitis patients? – Pharmaceutical Technology

Posted: Published on February 28th, 2024

The NaviCap targeted oral delivery platform, is an ingestible device approximately the size of a fish oil pill. Credit: Andrea Danti via Shutterstock. Therapies within the ulcerative colitis (UC) space are ever-evolving for the improvement of local, targeted therapy. Continue reading

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Biora Therapeutics completes first study phase for UC treatment By Investing.com – Investing.com

Posted: Published on February 28th, 2024

SAN DIEGO - Biora Therapeutics, Inc. (NASDAQ:BIOR), a biotech firm focused on innovative therapeutic delivery, has announced the completion of the single-ascending dose (SAD) cohorts in its phase 1 clinical trial of BT-600, a novel drug-device combination aimed at treating moderate to severe ulcerative colitis. The company is preparing to commence the multiple-ascending dose (MAD) cohorts in March, with expectations to share SAD data during its corporate update the same month Continue reading

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New Research Study for Patients With Ulcerative Colitis Now Available in Ogden, Utah – Chronicle-Tribune

Posted: Published on February 28th, 2024

State Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington Washington D.C. Continue reading

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miR-30c affects the pathogenesis of ulcerative colitis by regulating target gene VIP | Scientific Reports – Nature.com

Posted: Published on February 12th, 2024

Active ulcerative colitis patients and normal healthy control individuals The colon tissue samples of 4 active ulcerative colitis patients and 4 normal healthy controls were used to analyze miR-30c and VIP expression levels in this study, which were provided by the First Affiliated Hospital of Bengbu Medical College. The patients were included into this study according to the score of Sutherland Index (to describe the disease activity)37 and the modified Baron score (to represent an endoscopic classification)38. This study was approved by the Ethics Committee of Bengbu Medical College (No.2023LK401) and was conducted in accordance with the ethical guidelines of the Declaration of Helsinki. Continue reading

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Mood boosters reduce inflammation in IBD by 18%, study finds – News-Medical.Net

Posted: Published on January 27th, 2024

New King's College London research reveals that interventions which improve mood can reduce levels of inflammation in people with inflammatory bowel disease by 18 per cent, compared to having no mood intervention. Researchers at the Institute of Psychiatry, Psychology & Neuroscience at King's College London found that interventions designed to improve mood, including psychological therapy, antidepressants, and exercise, were associated with significant reductions in inflammatory biomarker levels in individuals with inflammatory bowel disease (IBD). Continue reading

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