Category Archives: Ulcerative Colitis

Ulcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD). Ulcerative colitis is a form of colitis, a disease of the colon (the largest portion of the large intestine), that includes characteristic ulcers, or open sores. The main symptom of active disease is usually constant diarrhea mixed with blood, of gradual onset. IBD is often confused with irritable bowel syndrome (IBS). Ulcerative colitis shares much in common with Crohn's disease, another form of IBD, but Crohn's disease can affect the whole gastrointestinal tract while ulcerative colitis only attacks the large intestine, and while ulcerative colitis can be cured by performing a total colectomy (i.e., removing the entire large intestine), surgery for Crohn's disease involves removing the damaged parts of the intestine and reconnecting the healthy parts, which does not cure Crohn's, as it can recur after surgery, mostly at the site of the intestinal anastomosis (connection) or in other areas. Ulcerative colitis is an intermittent disease, with periods of exacerbated symptoms, and periods that are relatively symptom-free. Although the symptoms of ulcerative colitis can sometimes diminish on their own, the disease usually requires treatment to go into remission. Ulcerative colitis has an incidence of 1 to 20 … Continue reading →

Ulcerative colitis facts Ulcerative colitis is an inflammation of the large intestine (colon). The cause of ulcerative colitis is unknown. Intermittent rectal bleeding, crampy abdominal pain and diarrhea often are symptoms of ulcerative colitis. The diagnosis of ulcerative colitis can be made with a barium enema, but direct visualization (sigmoidoscopy or colonoscopy) is the most accurate means of diagnosis. Long-standing ulcerative colitis is a risk factor for colon cancer. Treatment of ulcerative colitis may involve both medications and surgery. Ulcerative colitis also can cause inflammation in joints, spine, skin, eyes, and the liver and its bile ducts. What is ulcerative colitis? Ulcerative colitis is a chronic inflammation of the large intestine (colon). The colon is the part of the digestive system where water is removed from undigested material, and the remaining waste material is stored. The rectum is the end of the colon adjacent to the anus. In patients with ulcerative colitis, ulcers and inflammation of the inner lining of the colon lead to symptoms of abdominal pain, diarrhea, and rectal bleeding. Ulcerative colitis is closely related to another condition of inflammation of the intestines called Crohn's disease. Together, they are frequently referred to as inflammatory bowel disease (IBD). Ulcerative … Continue reading →

If you or someone you love have recently been diagnosed with ulcerative colitis, its important to begin learning as much as you can about what ulcerative colitis is. By developing a better understanding of ulcerative colitis, you will be more prepared to manage its symptoms and live a full life. Ulcerative colitis is a chronic disease of the large intestine, also known as the colon, in which the lining of the colon becomes inflamed and develops tiny open sores, or ulcers, that produce pus and mucous. The combination of inflammation and ulceration can cause abdominal discomfort and frequent emptying of the colon. Ulcerative colitis is the result of an abnormal response by your body's immune system. Normally, the cells and proteins that make up the immune system protect you from infection. In people with IBD, however, the immune system mistakes food, bacteria, and other materials in the intestine for foreign or invading substances. When this happens, the body sends white blood cells into the lining of the intestines, where they produce chronic inflammation and ulcerations. Its important to understand the difference between ulcerative colitis and Crohn's disease. Crohns disease can affect any part of the Gastrointestinal (GI) Tract, but ulcerative … Continue reading →

Due to unforeseen circumstances, publication orders cannot be taken or processed at this time. Publication ordering buttons and links will not work. On this page: Ulcerative colitis is a chronic, or long lasting, disease that causes inflammationirritation or swellingand sores called ulcers on the inner lining of the large intestine. Ulcerative colitis is a chronic inflammatory disease of the gastrointestinal (GI) tract, called inflammatory bowel disease (IBD). Crohn's disease and microscopic colitis are the other common IBDs. Read more in Crohn's Disease and Microscopic Colitis: Collagenous Colitis and Lymphocytic Colitis at http://www.digestive.niddk.nih.gov/ddiseases/topics/IBD.aspx. Ulcerative colitis most often begins gradually and can become worse over time. Symptoms can be mild to severe. Most people have periods of remissiontimes when symptoms disappearthat can last for weeks or years. The goal of care is to keep people in remission long term. Most people with ulcerative colitis receive care from a gastroenterologist, a doctor who specializes in digestive diseases. The large intestine is part of the GI tract, a series of hollow organs joined in a long, twisting tube from the mouth to the anusan opening through which stool leaves the body. The last part of the GI tract, called the lower GI tract, consists … Continue reading →

Ulcerative Colitis Ulcerative Colitis Overview Ulcerative colitis (UC) is an acute or chronic inflammation of the membrane that lines the colon (the large intestine or large bowel). The inflammation occurs in the inner most layer of the colon and may result in the formation of sores (ulcers). Ulcerative colitis rarely affects the small intestine except for the lower most section, called the terminal ileum. The inflammation makes the colon empty frequently causing diarrhea. Ulcers form in places where the inflammation has killed the cells lining the colon. The ulcers bleed and produce pus and mucus. Symptoms of ulcerative colitis include abdominal pain, diarrhea, rectal bleeding, a recurrent urge to have a bowel movement (tenesmus), lack of appetite, fever, and fatigue. Abdominal pain, diarrhea, and bloody bowel movements are the hallmark of the disease. The disease initially causes inflammation in the rectum and may gradually spread to involve the whole colon. If just the rectum is involved, it is referred to as ulcerative proctitis. Ulcerative colitis is one of the inflammatory bowel diseases (IBD), the other is Crohn's disease. Medically Reviewed by a Doctor on 11/14/2012 Go here to read the rest: Ulcerative Colitis: Facts on Symptoms, Treatment and Diet … Continue reading →

By RTT News, October 14, 2014, 07:13:00 AM EDT (RTTNews.com) - GW Pharmaceuticals Plc. ( GWPH ) (GWP.L) Tuesday announced preliminary topline results from a Phase 2a ulcerative colitis trial to be presented today at the company's R&D Day event in New York City. The Phase 2a pilot trial was a 10-week randomized, double-blind, placebo controlled study of GWP42003 extract, which features Cannabidiol or CBD as the primary cannabinoid and which also contains Tetrahyrdocannabinol or THC and other cannabinoid and non-cannabinoid components. The trial included 60 adult patients with ulcerative colitis who had not been able to gain remission from the condition, despite first line treatment with salicylates, and in some cases immunosuppressive therapy. GWP42003 was given as a twice daily oral capsule in a dose titration regimen, with an upper target dose of 250 mg twice daily. Due to the pilot nature of the study, and the small patient population, the significance value was set at p=0.1. The primary endpoint of this study was the percentage of participants achieving remission quantified by the MAYO score and included a range of secondary measures to determine whether GWP42003 has a positive benefit for subjects on symptom control. The study included 60 … Continue reading →