bit.ly The first comprehensive studies of genetic variation in head and neck squamous cell cancers have uncovered mutations that may help refine treatment for patients with the disease, according to researchers at The University of Texas MD Anderson Cancer Center. The two multi-institutional studies, both published online on the Science Express feature of the journal Science, found: • Mutations that affect an unexpected tumor-suppressing role of the NOTCH1 gene; • Infrequent but significant mutations in four suspected cancer-causing genes; and • Frequent mutation of the tumor-suppressing gene p53, which previously was known to be damaged or impaired in head and neck cancer.
Read the original here:
Dr. Jeffrey Myers Explains Genetic Variations in Head and Neck Cancer