New Data Highlighting Foundation Medicine’s Next-Generation Sequencing Approach in Clinical Oncology to be Presented …

Foundation Medicine, Inc., a molecular information company that brings comprehensive cancer genomic analysis to routine clinical care, today announced that new data highlighting the companys next-generation sequencing approach in clinical oncology will be presented at the 103rd American Association for Cancer Research (AACR) Annual Meeting 2012 being held March 31 through April 4 in Chicago.

The presentations will highlight the technical feasibility and clinical relevance of the companys next-generation sequencing platform for oncology, which offers a fully informative genomic profile of the relevant alterations present in about 200 genes known to be somatically altered in human cancers. In these studies, the profile demonstrated concordance with existing commercial offerings and identified all classes of genomic alterations. In one study being presented, approximately 70 percent of cases were found to carry one or more actionable alterations, meaning the alteration could plausibly confer sensitivity or resistance to approved or experimental targeted therapies. The studies also identified more classes of alterations, including base pair mutations, insertions and deletions, copy number alterations and select gene fusions and rearrangements, than other commercially available molecular diagnostic tests.

The data presented at AACR show that thebreadth and relevanceof Foundation Medicines genomic profile may offer important information for cancer treatment decisions, while fitting easily into routine clinical practice,said Vincent Miller, M.D., senior vice president, clinical development, Foundation Medicine. These findings support the feasibility of our fundamental mission to help practicing oncologists integrate the unique molecular information for each patients tumor into clinical decision making.

The schedule for Foundation Medicines presentations and posters is as follows:

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New Data Highlighting Foundation Medicine’s Next-Generation Sequencing Approach in Clinical Oncology to be Presented ...