Search Results for: stroke recovery treatments 2013

-- CHIMES Society, a unique international partnership of experts in strokes undertakes first large-scale endeavour to investigate the use of a treatment derived from natural substances in stroke management -- Rigorous study shows ischemic stroke patients of intermediate severity who take NeuroAiD at acute stage had an 11 % increase in the odds of achieving independence and being able to perform daily activities at the end of three months -- Effect was even greater when NeuroAiD was started beyond 48 hours after stroke onset, with an increase of 39%. SINGAPORE, June 21, 2013 /PRNewswire/ --NeuroAiD, a stroke treatment based on Traditional Chinese Medicine, increases the odds of achieving a better functional outcome, according to research published online in the journal Stroke. The CHIMES study is an academic international double-blind placebo-controlled clinical trial which included 1100 patients from several countries who had suffered an ischemic stroke of intermediate severity within 72 hours, treated and monitored for 3 months. Researchers found that patients who were taking NeuroAiD at acute stage had an 11% increase in the odds of achieving independence in function and being able to perform daily activities at the end of three months. This effect was even greater when NeuroAiD … Continue reading →

SINGAPORE, June 20, 2013 /PRNewswire/ -- NeuroAiD, a stroke treatment based on Traditional Chinese Medicine, increases the odds of achieving a better functional outcome, according to research published online in the journal Stroke. The CHIMES study is an academic international double-blind placebo-controlled clinical trial which included 1,100 patients from several countries who had suffered an ischemic stroke of intermediate severity within 72 hours, treated and monitored for 3 months. Researchers found that patients who were taking NeuroAiD at acute stage had an 11% increase in the odds of achieving independence in function and being able to perform daily activities at the end of three months. This effect was even greater when NeuroAiD was started beyond 48 hours after stroke onset, with an increase of 39%. The odds ratio was the highest among recently completed stroke trials of neuroprotective agents. The benefit observed is clinically relevant and might have reached statistical significance with a larger sample size. In addition the study confirmed the excellent safety profile of NeuroAiD. Stroke survivors who were on NeuroAiD had fewer adverse events than those in the control group. Further studies will likely look into the benefits of longer duration of treatment. Prof. Christopher Chen, neurologist … Continue reading →

June 13, 2013 A specific MicroRNA, a short set of RNA (ribonuclease) sequences, naturally packaged into minute (50 nanometers) lipid containers called exosomes, are released by stem cells after a stroke and contribute to better neurological recovery according to a new animal study by Henry Ford Hospital researchers. The important role of a specific microRNA transferred from stem cells to brain cells via the exosomes to enhance functional recovery after a stroke was shown in lab rats. This study provides fundamental new insight into how stem cells affect injured tissue and also offers hope for developing novel treatments for stroke and neurological diseases, the leading cause of long-term disability in adult humans. The study is being published in the journal Stem Cells. Although most stroke victims recover some ability to voluntarily use their hands and other body parts, nearly half are left with weakness on one side of their body, while a substantial number are permanently disabled. Currently no treatment exists for improving or restoring this lost motor function in stroke patients, mainly because of mysteries about how the brain and nerves repair themselves. "This study may have solved one of those mysteries by showing how certain stem cells play … Continue reading →

Public release date: 13-Jun-2013 [ | E-mail | Share ] Contact: Dwight Angell dwight.angell@hfhs.org 313-850-3471 Henry Ford Health System DETROIT A specific MicroRNA, a short set of RNA (ribonuclease) sequences, naturally packaged into minute (50 nanometers) lipid containers called exosomes, are released by stem cells after a stroke and contribute to better neurological recovery according to a new animal study by Henry Ford Hospital researchers. The important role of a specific microRNA transferred from stem cells to brain cells via the exosomes to enhance functional recovery after a stroke was shown in lab rats. This study provides fundamental new insight into how stem cells affect injured tissue and also offers hope for developing novel treatments for stroke and neurological diseases, the leading cause of long-term disability in adult humans. The study, to be published in the journal Stem Cells, is available at http://www.ncbi.nlm.nih.gov/pubmed/23630198. Although most stroke victims recover some ability to voluntarily use their hands and other body parts, nearly half are left with weakness on one side of their body, while a substantial number are permanently disabled. Currently no treatment exists for improving or restoring this lost motor function in stroke patients, mainly because of mysteries about how the … Continue reading →

Featured Article Main Category: Stroke Also Included In: Stem Cell Research;Clinical Trials / Drug Trials Article Date: 28 May 2013 - 3:00 PDT Current ratings for: Stroke Patients Show Signs Of Recovery Following Stem Cell Trial 4.67 (3 votes) 4 (1 votes) Updated interim results of the Pilot Investigation of Stem Cells in Stroke (PISCES) study, which is testing the safety and tolerability of injecting neural stem cells into the brains of ischemic stroke patients, were reported on Monday at the 22nd European Stroke Conference in London. The stem cell trial started in 2010, with one stroke patient, an elderly Scotsman who was injected with ReN001 cells developed by ReNeuron Group plc, at the trial center at Southern General Hospital in Glasgow, UK. By 2012, there were six patients on the small trial, and an early set of results presented at an international conference showed that five of the six patients were showing some improvement and there had been no adverse side effects. Clare Walton, Research Communications Officer at the UK's Stroke Association says they are very excited about the results of the trial, but "we are currently at the beginning of a very long road and significant further development … Continue reading →

Belleville, IL (PRWEB) May 10, 2013 Every 40 seconds, someone in the U.S. has a stroke. Allsup, a nationwide provider of Social Security Disability Insurance (SSDI) representation, veterans disability appeal and Medicare plan selection services is pleased to sponsor the National Stroke Associations Act FAST for Stroke Challenge to help raise awareness and funds. A stroke happens when blood flow to a part of the brain stops, depriving it of oxygen and killing brain cells. Permanent brain damage can result. Stroke is a leading cause death and disability, causing paralysis, speech difficulties, muscle and nerve problems, cognitive difficulties and other disabling conditions. Lack of awareness of stroke signs and symptoms among the general public is a huge challenge, said Jim Baranski, CEO of the National Stroke Association. National Stroke Awareness Month is a great opportunity to work together to raise support and awareness in the community. The National Stroke Association encourages the public to act and think FAST when it comes to stroke. The sooner an individual gets emergency medical treatment, the better their odds are for survival and recovery. Face: Ask the person to smile. Does one side of the face droop? Arms: Ask the person to raise both … Continue reading →

ARDSLEY, N.Y.--(BUSINESS WIRE)-- Acorda Therapeutics, Inc. (Nasdaq: ACOR) today announced that data showing treatment with dalfampridine improved motor function in a preclinical model of post-stroke deficits have been published online ahead of print on May 7th in Stroke, a peer-reviewed journal of the American Heart Association. The data will be included in the July 2013 print edition of Stroke. Dalfampridine is the active ingredient in AMPYRA (dalfampridine) Extended Release Tablets, 10 mg. These preclinical data showed that dalfampridine can improve motor function long after a stroke, when the natural recovery process has ended and stable deficits are likely to persist over time. The results informed our decision to conduct a recently completed proof-of-concept study in humans, which indicated that dalfampridine improved walking in people with post-stroke deficits, said Andrew R. Blight, Ph.D., Acorda Therapeutics Chief Scientific Officer. More than half of the nearly seven million people in the United States who live with the long term effects of a stroke have lasting mobility impairment, but there are no established treatments other than physical therapy to address these impairments. New therapies are needed, and we are moving forward with development of dalfampridine extended release tablets in this indication. The paper, entitled … Continue reading →

SINGAPORE, March 19, 2013 /PRNewswire/ --Authors of a medical paper published in this month's Cerebrovascular Diseases journal found that NeuroAiD, developed by Moleac, significantly improves patients' independence after suffering a stroke compared to other control groups. During the studies stroke patients taking NeuroAiD were twice as likely able to take care of themselves and speak freely. The study also showed that NeuroAiD improved patients' chances of performing daily activities after stroke. Stroke is one of the leading causes of death worldwide and occurs every 2 seconds. Each year, 20 million people suffer from the devastating disease. There are only few effective, generally accepted and specific treatments for stroke, like thrombolytic treatment for highly selected patients. Therefore, there is an increasing need for multi-model therapies to help more patients recover quickly and effectively from stroke. Herbal supplements have been demonstrated to have antioxidant, anti-inflammatory, and anti-glutamate effects, making them an attractive option to be investigated for stroke recovery. Thus, as Dr. Christopher Chen, one of the authors of the paper, says, "confirmation of the effectiveness of herbal supplements could have a great impact on stroke management". The paper updates the meta-analysis, published in Stroke journal in 2009 to include all clinical … Continue reading →