PLOS Genetics: A Peer-Reviewed Open-Access Journal

01/14/2016

research article

Sensory neuron diversity is required for organisms to decipher complex environmental cues. Qingyun Li and colleagues highlight the importance of the early prepatterning gene regulatory network as a modulator ofsensory organ precursorand terminally differentiated olfactory receptor neurondiversity in Drosophila.

01/20/2016

research article

Telomeres shorten with each cell division and telomere dysfunction is a recognized hallmark of aging. Madalena Carneiro and colleagues show that telomere shortening and DNA damage in key tissues triggers not only local dysfunction but also anticipates the onset of age-associated diseases in other tissues, including cancer.

01/20/2016

research article

The thymic medulla is known to be an essential site for the deletion of auto-reactive T cells. Rumi Satoh and colleagues show thatStat3 meditated signal via EGF-R is required for the postnatal development of thymic medullary regions.

01/21/2016

Viewpoints

Stephanie Dyke and colleagues examine the variation in data use conditions that are based on consent provisions for genomics datasets in research and clinical settings.

Image credit: Duncan Hull, Flickr, CC BY

Image credit: K. Adam Bohnert and Kathleen Gould

Image credit: Hey Paul Studios, Flickr, CC BY

12/23/2015

review

Albino Bacolla and colleagues discuss recent advances on three-stranded (triplex) nucleic acids, with an emphasis on DNARNA and RNARNA interactions.

Image credit: mira66, Flickr, CC BY

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PLOS Genetics: A Peer-Reviewed Open-Access Journal