Poster : The identity and properties of mesenchymal stem cells

Csar Nombela-Arrieta and Leslie E. Silberstein

Mesenchymal stem cells (MSCs) are multipotent progenitor cells that were originally identified in the bone marrow stroma, where they regulate key stages of haematopoiesis. They have since been identified in other anatomical locations, although their physiological roles remain unclear. MSCs can be expanded in vitro and, under appropriate conditions, can give rise to several cell types, including bone and fat precursors. The in vitro-expanded cells have remarkable immunoregulatory properties and effects on tissue repair; because of this, their potential use as therapeutic agents in vivo is being extensively studied.

This Poster by Csar Nombela-Arrieta and Leslie E. Silberstein provides an overview of the identity of MSCs in vivo and the effects of their in vitro-expanded progeny, and highlights key questions that remain in the field regarding the biology of these elusive cells.

The Poster is freely available thanks to support from STEMCELL Technologies Inc.

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Poster : The identity and properties of mesenchymal stem cells