Research and Markets: PharmaPoint Drug Evaluation Report – Banzel / Inovelon ( Epilepsy ) – Forecast and Market Analysis …

Posted: Published on March 14th, 2013

This post was added by Dr Simmons

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/lxx543/banzel__inovelon) has announced the addition of GlobalData's new report "Banzel / Inovelon (Epilepsy) - Forecast and Market Analysis to 2022" to their offering.

PharmaPoint Drug Evaluation Report - Banzel / Inovelon (Epilepsy) - Forecast and Market Analysis to 2022. Epilepsy is a brain disorder characterized by spontaneously occurring and recurrent seizures. The market is heavily driven by the sales of antiepileptic drugs (AEDs) targeted at seizure reduction. The AED market is currently dominated by UCB's Keppra and GlaxoSmithKline's Lamictal. Although both drugs have experienced significant generic erosion, they form the mainstay of epilepsy treatment in the nine markets and will continue to have significant market share during the forecast period.

Other key drugs include older generation AEDs such as Pfizer's Dilantin, Abbott's Depakote, and Novartis' Tegretol and Trileptal which still have significant usage due to their longevity in the market. However, the AED dominance landscape will continue to shift towards newer generation drugs particularly following the recent market entry of GlaxoSmithKline's Trobalt/Potiga and Eisai's Fycompa which both offer first-in-class mechanisms of action.

Banzel (rufinamide) is an AED that was originally developed by Novartis. In 2004, Eisai acquired the rights to develop, manufacture, and market the drug worldwide. Rufinamide is marketed in North America as Banzel, and in the EU under the brand name Inovelon. The drug is used to treat seizures associated with LGS, a severe form of epilepsy in children and adults, and is available as film-coated tablets and a suspension for oral administration. Rufinamide is a sodium channel inhibitor, but as a triazole derivative it is structurally unrelated to the currently marketed AEDs that also inhibit sodium channels. Although its precise MOA is unknown, in-vitro studies indicate that rufinamide significantly slows sodium channel recovery from inactivation and limits sustained repetitive firing of neurons.

Scope

- Overview of Epilepsy, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.

- Detailed information on Banzel / Inovelon including product description, safety and efficacy profiles as well as a SWOT analysis.

- Sales forecast for Banzel / Inovelon for the top seven countries from 2012 to 2022.

- Sales information covered for the US, France, Germany, Italy, Spain, the UK and Japan

See more here:
Research and Markets: PharmaPoint Drug Evaluation Report - Banzel / Inovelon ( Epilepsy ) - Forecast and Market Analysis ...

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