This is an annual report of registered clinical trials in cell therapy. Every year I overview some tracked data from international clinical trials databases. You can see 2011 report here.
Definitions I tracked clinical trials which fall in definition of cell therapy: administration of living cells in human with therapeutic purpose. I included tissue engineering, cellular gene therapy and devices for cell processing. I tracked all clinical trials which were registered from Jan.1, 2012 to Dec. 31, 2012 in international databases.
Exclusion criteria: Trials, assessing cell therapy for homologous use were excluded from analysis. Examples: (1) hematopoietic cells for recovery of blood formation (in hematological malignancies) or (2) ex vivo expansion of hematopoietic cells for enhancement of engraftment in hematological malignancies.
Hand coding and data collection Hand coding included:
Search key words: cell therapy stem cell cord blood umbilical cord bone marrow cancer vaccine tissue engineering
Total number of trials tracked: 226 Number of duplications between databases: 6
Databases The following databases were scanned: US NCT (NIH-FDA) European EUCTR Japanese JPRN Indian CTRI Chinese ChiTCR Iranian IRCT Australian/NZ ANZCTR UK ISRCTN Dutch NTR South Korean CRIS
All international databases, except NCT, were scanned via WHO Search Portal. Databases representation:
Demographics:
Read more:
Stem Cell Blog - Cell therapy clinical trials – 2012 report ...
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