DURHAM N.C. May. 27 2015 /PRNewswire-iReach/ A new study appearing today inSTEM CELLS Translational Medicinedesigned to test how stem cell injections affect primates with spinal cord injury (SCI) showed the treatments significantly improved the animals motor function recovery and promoted faster healing too. The researchers call their findings a step forward toward the goal of improving outcomes for humans with chronic SCI.
Previous research conducted by various groups had indicated stem cell treatments helped rats with SCI. But because there are distinct differences in the nervous system and immunological responses between rodents and primates it is critical to determine how effective and safe the injections might be in a non-human primate SCI model as part of the translational research required for clinical trials explained Hideyuki Okano M.D. Ph.D. of Keio University School of Medicines physiology department and a co-author of the new study.
In this study the researchers grafted neural stem/progenitor cells (NS/PCs)derived from marmoset (a type of monkey) embryonic stem cells into adult marmosets suffering from a moderately bruised spinal cord. The advantage of using common marmosets is the similarity between their nervous system and immunological responses and those of humans Dr. Okano said.
The injections were given 14 days after the SCI occurred which research shows is an optimal time window for SCI therapy as inflammation has generally subsided by then and scar tissue has not yet had time to form.(Doctors believe that an incomplete spinal cord injury such as those of the study animals offers better chance for recovery than a complete SCI injury.) The results were promising.
Eventually motor function recovery significantly improved in the transplantation group compared to a control group that did not receive stem cells reported co-author Masaya Nakamura M.D. Ph.D. of Keios Department of Orthopedic Surgery. An animal in the control group for example could not raise her hands up to head height at 12 weeks after injury when motor function almost plateaus. On the other hand at the same point in time a transplanted animalwas able to jump successfully and run so fast it was difficult for us to catch her. She could also grip a pen at 3 cm. above head-height.
In addition he added there were no signs of immune rejection or tumors which have been a side effect of some stem cell therapies.
The researchers say this study is a step forward in their goal is to improve patients with complete SCI at the chronic phase. But we believe it will require a combination of stem cell transplantation rehabilitation and pharmacological therapy with the stem cells a key part of the treatment Dr. Okano added.
This translational research using a nonhuman primate model is a critical step in eventually applying these cells to injured spinal cord in human patients said Anthony Atala M.D. Editor-in-Chief ofSTEM CELLS Translational Medicineand director of the Wake Forest Institute for Regenerative Medicine.
Read the original:
Stem Cell Treatment Speeds Up Recovery after Spinal Cord ...
- Dr. Oz to Oprah and Michael J Fox: "The stem cell debate is dead." - March 13th, 2011 [March 13th, 2011]
- COPD and Stem Cell Treatments - www.StemCellRegenMed.com - April 2nd, 2011 [April 2nd, 2011]
- Stem Cell Treatments - Future Research - April 6th, 2011 [April 6th, 2011]
- Stem Cell Treatment - Current Research - May 11th, 2011 [May 11th, 2011]
- Brain Damage and Stem Cell Treatments - www.stemcellregenmed.com - May 20th, 2011 [May 20th, 2011]
- Stem Cell Treatments and COPD - WWW.STEMCELLREGENMED.COM - May 23rd, 2011 [May 23rd, 2011]
- Adult Stem Cell treatments center - American Stem Cell - May 30th, 2011 [May 30th, 2011]
- Pt. 2--Dr. Darwin Prockop--Adult Stem Cell Treatments - May 31st, 2011 [May 31st, 2011]
- Mother Shares Her Children's Story of Stem Cell Treatments for Autism - June 1st, 2011 [June 1st, 2011]
- Stem cell treatments and rejection reactions - June 1st, 2011 [June 1st, 2011]
- Interview with Dr. Feinerman Stem Cell Treatments and Tay Sachs disease www.stemcellregenmed.com - June 2nd, 2011 [June 2nd, 2011]
- The success rate of stem cell treatments for diabetes - June 12th, 2011 [June 12th, 2011]
- Stem Cell Treatments for Autism: Community Outreach Miami, Florida - Juliana Ubinas - June 13th, 2011 [June 13th, 2011]
- Tay-Sachs Disease and Stem Cell Treatments WWW.STEMCELLREGENMED.COM - June 20th, 2011 [June 20th, 2011]
- Stem Cell Therapy for Spinal Cord Injury - Injured Airline Pilot Flies Again - June 23rd, 2011 [June 23rd, 2011]
- A Dose of Reality on Alternative Stem Cell Treatments: What you don't know can hurt you - July 11th, 2011 [July 11th, 2011]
- Stem Cell City - Lisa Ray - July 15th, 2011 [July 15th, 2011]
- Stem Cell Treatment for Cerebral Palsy at the XCell-Center in Germany - September 10th, 2011 [September 10th, 2011]
- A Touch of Love® - InGeneron - Stem Cell Therapy Interview - September 26th, 2011 [September 26th, 2011]
- A Touch of Love® - Stem Cell Therapy for Thomas a Dogue De Bordeaux - September 27th, 2011 [September 27th, 2011]
- The Spinal Cord Journey - Stem cell therapy stories from three spinal cord injury patients - October 5th, 2011 [October 5th, 2011]
- Cerebral Palsy - October 5th, 2011 [October 5th, 2011]
- Stem Cell Health Alliance - Breakthrough to Independence - October 6th, 2011 [October 6th, 2011]
- ALS Patient Interview, Stem Cell Treatments and ALS www.stemcellregenmed.com - Video - November 13th, 2011 [November 13th, 2011]
- Yankees Pitcher Receives Adult Stem Cell Therapy for Shoulder Injury - Video - November 16th, 2011 [November 16th, 2011]
- Innovative stem cell treatment for Spinal Cord Injuries - Video - January 13th, 2012 [January 13th, 2012]
- Stem Cell Therapy - Medistem Labs Panama Laboratory Tour - Video - January 23rd, 2012 [January 23rd, 2012]
- Adult Stem Cell Treatments for COPD -Real patient results, USA Stem Cells- Shirlen M. Testimonial - Video - January 23rd, 2012 [January 23rd, 2012]
- Adult Stem Cell Treatments for COPD -Real patient results, USA Stem Cells- Leon B. Testimonial - Video - January 23rd, 2012 [January 23rd, 2012]
- Adult Stem Cell Treatments for COPD - Real patient results, USA Stem Cells - Marian H. Testimonial - Video - January 24th, 2012 [January 24th, 2012]
- Stem Cell Treatments - Video - February 7th, 2012 [February 7th, 2012]
- Documenting THE CURE: Seeking Stem Cell Healing Offshore -- MS patient - Video - February 20th, 2012 [February 20th, 2012]
- The Alliance for Regenerative Medicine Statement on Use of Cell Therapies Not Approved by the Federal Drug ... - March 6th, 2012 [March 6th, 2012]
- ETX mom hopes 'Joel's Journey for Sight' leads to China - March 6th, 2012 [March 6th, 2012]
- Nuvilex Forecasts Vast Partnership Opportunities Using Breakthrough Stem Cell Technology - March 6th, 2012 [March 6th, 2012]
- Unveilling stem cells - June 15th, 2012 [June 15th, 2012]
- FDA: Stem cell lab used by Perry has problems - June 26th, 2012 [June 26th, 2012]
- Stem Cells Restore Hearing In Deaf Gerbils - September 14th, 2012 [September 14th, 2012]
- Rylan heads to China soon - September 16th, 2012 [September 16th, 2012]
- Health Link Medical Center Introduces the Regenexx™ Orthopedic Stem Cell Treatments to the San Francisco Area - October 2nd, 2012 [October 2nd, 2012]
- Stem-cell advocacy ‘moved the needle’ - October 2nd, 2012 [October 2nd, 2012]
- Realizing the potential of stem cell therapy - October 16th, 2012 [October 16th, 2012]
- RBCC: Could Stem Cells Be Key to Promising Autism Therapy? - October 17th, 2012 [October 17th, 2012]
- DOH warns public vs stem cell therapies - October 23rd, 2012 [October 23rd, 2012]
- FAQ-8 of 19: Do Stem Cells Have Side Effects In Stem Cell Therapy? - Video - November 1st, 2012 [November 1st, 2012]
- FAQ-8 of 19: With Stem Cell Therapy Are There Any Stem Cell Side Effects? - Video - November 1st, 2012 [November 1st, 2012]
- FAQ-8 of 19: In Stem Cell Therapy Do Stem Cells Cause Side Effects? - Video - November 1st, 2012 [November 1st, 2012]
- FAQ-4 19- What Probability of Stem Cell HELP When I Take Stem Cell Treatments? - Video - November 1st, 2012 [November 1st, 2012]
- HIV and IDS Cure Reality With Stem Cell Treatments - Video - November 1st, 2012 [November 1st, 2012]
- stem cell AIDS cure by Stem Cell Treatments - Video - November 1st, 2012 [November 1st, 2012]
- 'German AIDS Cure' Means Stem Cell Treatments in Thailand, Under License - Video - November 1st, 2012 [November 1st, 2012]
- HIV and AIDS Cure With Stem Cell Treatments - Video - November 1st, 2012 [November 1st, 2012]
- Stem Cell Aids Cure Not Always, But Frequently - Video - November 1st, 2012 [November 1st, 2012]
- Quick Surgeon Profile - Stem Cells Specialist in Mexico - Video - November 1st, 2012 [November 1st, 2012]
- Heart Health - November 1st, 2012 [November 1st, 2012]
- Our adventure - Video - November 1st, 2012 [November 1st, 2012]
- Stem Cell Treatments Hold Hope for HIV-AIDS - Video - November 1st, 2012 [November 1st, 2012]
- Stem Cell Treatments Showing Great Results HIV-AIDS - Video - November 1st, 2012 [November 1st, 2012]
- Skin deep - Catalyst story on fat transfer and stem cell treatments - Video - November 1st, 2012 [November 1st, 2012]
- Disclosure Stem Cell Treatments and Heart Disease Part 2 - Video - November 1st, 2012 [November 1st, 2012]
- Disclosure Stem Cell Treatments and Heart Disease Part 1 - Video - November 1st, 2012 [November 1st, 2012]
- Research and Markets: Commercializing the Stem Cell Sciences - November 3rd, 2012 [November 3rd, 2012]
- FAQ-14 of 19: Do We Provide a Guarantee for Stem Cell Therapy? - Video - November 3rd, 2012 [November 3rd, 2012]
- FAQ-14 of 19: Your Stem Cell Therapy Has a Guarantee for Stem Cell Treatments? - Video - November 5th, 2012 [November 5th, 2012]
- FAQ-14-19: Does Your Stem Cell Clinic Guarantee Stem Cell Therapy? - Video - November 5th, 2012 [November 5th, 2012]
- FAQ-13-19: How Many Stem Cell Treatments Are Right Stem Cell Therapies for Me? - Video - November 5th, 2012 [November 5th, 2012]
- FAQ-14 of 19: Do Your Stem Cell Doctors Offer a Guarantee for Stem Cell Therapy? - Video - November 5th, 2012 [November 5th, 2012]
- FAQ-13 of 19: How Many Stem Cell Treatments Should I Have? - Video - November 5th, 2012 [November 5th, 2012]
- FAQ-11 of 19: For Stem Cell Therapy, Why Thailand's Licensed Stem Cell Treatments? - Video - November 5th, 2012 [November 5th, 2012]
- cord blood | Cord Blood Banking - Your Biological Insurance Policy - Video - November 7th, 2012 [November 7th, 2012]
- jodyMSvideo2012 0001 - Video - November 16th, 2012 [November 16th, 2012]
- Therafit Gym Multiple Sclerosis Jody MS (stem cell trial).wmv - Video - November 20th, 2012 [November 20th, 2012]
- World Renowned Stem Cell Therapist Lectures Around the World - November 24th, 2012 [November 24th, 2012]
- Guillaume Leblanc - Video - November 29th, 2012 [November 29th, 2012]
- Autologous Cell Therapy Market expected to reach $2.2 billion by 2017, growing at a CAGR of 21% : MarketsandMarkets - December 3rd, 2012 [December 3rd, 2012]
- Stem Cell Treatments for Rheumatoid Arthritis and MS at Stem Cell Institute in Panama: Tracey R. - Video - March 15th, 2013 [March 15th, 2013]
- Stem Cell Treatments March 23, 2013 - Video - March 28th, 2013 [March 28th, 2013]
- Rejuv Medical Announces Stem Cell Treatments Now Available - April 9th, 2013 [April 9th, 2013]
- Stem Cell Treatments for Rheumatoid Arthritis - Arminda Bourin - Video - April 13th, 2013 [April 13th, 2013]
- Stem Cell Treatments for Spinal Cord Injury: Theo K. - Stem Cell Institute Panama - Video - May 3rd, 2013 [May 3rd, 2013]