The groundbreaking 'genetic guidebook for humans' that could lead to radical new personalised treatments for …

Posted: Published on November 2nd, 2012

This post was added by Dr Simmons

Project puts together genetic data from more than 1,000 people around the world Groundbreaking research paves the way for personalised cures

By Mark Prigg

PUBLISHED: 13:52 EST, 31 October 2012 | UPDATED: 13:52 EST, 31 October 2012

Scientists have created a map of gene mutations in more than 1,000 people around the world in a breakthrough that could lead to new treatments for cancer, heart disease and other illnesses.

The 1,000 Genomes Project which compares the DNA of participants from fourteen different populations also brings targeted, individualised therapy for patients a step closer.

By mapping the differences in our make-up researchers can understand why some people may be more susceptible to inherited disease or other genetic conditions.

Scientists have created a map of gene mutations in more than 1,000 people around the world - a breakthrough that could lead to new treatments for cancer, heart disease and other illnesses

It took the international team - including British scientists - five years to sequence the complete DNA of 1,092 individuals in England and Scotland as well as Africa, East Asia, the Americas and other European countries.

Professor Aravinda Chakravarti, of the Johns Hopkins School of Medicine in Baltimore, said: 'The DNA donors in the study were not known to have any diseases so the study gives us the genomic background we need for understanding which genetic variations are within the normal range.

'With this tool, scientists now have a standard with which they can compare the genome of someone with diabetes, for example.'

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