5-HT2B Antagonist Market Economic impact analysis of Covid-19 on the market: along with a historic view from 2015 and a long-term forecast until 2026…

GLOBAL 5-HT2B Antagonist INSIGHTS, FORECAST TO 2026

Global 5-HT2B Antagonist Market research report provides an excellent vision to analyze Global as well as regional industry. This research report delivers a detailed analysis by using various methods like SWOT Analysis, PEST Analysis, and Porters 5 Forces Model to bestow strategies for industrial growth that will help to determine factors like major industry vendors, key regions, demand & supply, applications, innovations, revenue cost, and challenges, trends, restraints, and drivers. These Factors will help to determine Global Business Scope for 5-HT2B Antagonist Market.

Market Dynamics like CAGR, Competition by Revenue, Price Trend, Market Share, Market Size, Inventory Turnover, etc. are provided through qualitative and quantitative analysis, which renders a cavernous understanding of the market to the readers, business owners, and industry experts.

5-HT2B Antagonist Market Competitive Insights(Key Players):

Eli Lilly

Egis Pharmaceuticals

Pfizer

AcurePharma

& list continues

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The serotonin (5-HT) pathway was shown to play a role in pulmonary hypertension (PH), but its functions in right ventricular failure (RVF) remain poorly understood. The aim of the current study was to investigate the effects of Terguride (5-HT2A and 2B receptor antagonist) or SB204741 (5-HT2B receptor antagonist) on right heart function and structure upon pulmonary artery banding (PAB) in mice.Methods. Seven days after PAB, mice were treated for 14 days with Terguride (0.2mg/kg bid) or SB204741 (5mg/kg day). Right heart function and remodeling were assessed by right heart catheterization, magnetic resonance imaging (MRI), and histomorphometric methods. Total secreted collagen content was determined in mouse cardiac fibroblasts isolated from RV tissues.Results. Chronic treatment with Terguride or SB204741 reduced right ventricular fibrosis and showed improved heart function in mice after PAB. Moreover, 5-HT2B receptor antagonists diminished TGF-beta1 induced collagen synthesis of RV cardiac fibroblastsin vitro.Conclusion. 5-HT2B receptor antagonists reduce collagen deposition, thereby inhibiting right ventricular fibrosis. Chronic treatment prevented the development and progression of pressure overload-induced RVF in mice. Thus, 5-HT2B receptor antagonists represent a valuable novel therapeutic approach for RVF.

Regional Analysis for 5-HT2B Antagonist

The report provides a detailed breakdown of the market region-wise and categorizes it at various levels. Regional segment analysis displaying regional production volume, consumption volume, revenue, and growth rate from 2020-2026 covers:

Americas (United States, Canada, Mexico, Brazil),

APAC (China, Japan, Korea, Southeast Asia, India, Australia),

Europe (Germany, France, UK, Italy, Russia, Spain),

Middle East & Africa (Egypt, South Africa, Israel, Turkey, GCC Countries).

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Key Assessments Patient Segmentation Disease Risk and Burden Risk of disease by the segmentation Factors driving growth in a specific patient population

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5-HT2B Antagonist Market Economic impact analysis of Covid-19 on the market: along with a historic view from 2015 and a long-term forecast until 2026...