Aggressive blood pressure management associated with a lower risk of heart attack, heart failure, death from CVD – Cardiovascular Business

Posted: Published on May 25th, 2021

This post was added by Alex Diaz-Granados

Aggressive blood pressure managementtargeting a systolic blood pressure (SBP) less than 120 mm Hgis associated with much better cardiovascular outcomes than taking a more traditional approach, according to new findings published in the New England Journal of Medicine.

The analysis represented a fresh look at data from the SPRINT study, which was originally completed back in 2015. Researchers were able to include additional data in this update, including new findings from an observational post-intervention period.

The SPRINT study was sponsored by the National Heart, Lung and Blood Institute and enrolled more than 9,000 adults with a SBP of 130 to 180 mm HG. All patients were 50 years old or older.

Overall, the studys authors reported that targeting a SBP of less than 120 mm HG provided significantly more value than targeting a SBP less than 140 mm HG. In fact, the more aggressive approach was associated with a 27% lower risk of the studys primary outcome, a composite of outcomes that included myocardial infarctions, acute coronary syndrome not resulting in a myocardial infarction, stroke, acute heart failure and death from cardiovascular disease.

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Aggressive blood pressure management associated with a lower risk of heart attack, heart failure, death from CVD - Cardiovascular Business

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