Category Archives: Cardiac Remodeling

March 04, 2021 11:00 ET | Source: Berlin Heals Holding AG BERLIN and ZUG, Switzerland, March 04, 2021 (GLOBE NEWSWIRE) -- BERLIN HEALS, a company dedicated to developing and offering novel and life-saving treatments for patients suffering from heart failure, announces results of a first-in-human study published in ESC Heart Failure, in patients with dilated cardiomyopathy for its proprietary C-MIC device. The C-MIC is a small implantable device that delivers a minimal constant electrical DC current to the heart. The results show significant, rapid improvements in heart function, heart size and quality of life of patients. Continue reading →

Parveen K Garg,1 Traci M Bartz,2 Gregory Burke,3 John S Gottdiener,4 David Herrington,5 Susan R Heckbert,6 Jorge R Kizer,7,8 Nona Sotoodehnia,9 Kenneth J Mukamal10 1Division of Cardiology, University of Southern California Keck School of Medicine, Los Angeles, CA, USA; 2Department of Biostatistics, University of Washington, Seattle, WA, USA; 3Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA; 4Cardiology Division, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA; 5Departments of Cardiology, Epidemiology and Prevention, Wake Forest University, Winston-Salem, NC, USA; 6Cardiovascular Health Research Unit and Department of Epidemiology, University of Washington, Seattle, WA, USA; 7Cardiology Section, San Francisco Veterans Affairs Health Care System, San Francisco, CA, USA; 8Departments of Medicine, and Epidemiology and Biostatistics, University of California, San Francisco, CA, USA; 9Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, WA, USA; 10Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA Correspondence: Parveen K Garg Division of Cardiology, University of Southern California Keck School of Medicine, 1510 San Pablo St. Suite 322, Los Angeles, CA, 90033, USA Tel +1 323-442-6131 Fax +1 323-442-6133 Email parveeng@med.usc.edu Background: Endothelial dysfunction is associated with common risk factors for AF and has been implicated in the pathophysiology of atrial fibrillation (AF) through a variety of mechanisms. We determined the prospective association of brachial flow-mediated dilation (FMD) with incident AF among older adults. Continue reading →

GLOBAL 5-HT2B Antagonist INSIGHTS, FORECAST TO 2026 Global 5-HT2B Antagonist Market research report provides an excellent vision to analyze Global as well as regional industry. This research report delivers a detailed analysis by using various methods like SWOT Analysis, PEST Analysis, and Porters 5 Forces Model to bestow strategies for industrial growth that will help to determine factors like major industry vendors, key regions, demand & supply, applications, innovations, revenue cost, and challenges, trends, restraints, and drivers. Continue reading →

The research report on global Absorbable Heart Stent Market is a comprehensive guide for new market entrants. Continue reading →

Visit the News Hub Washington University researchers part of team probing inflammation after heart attack Inflammatory cells are visible as colored areas in this PET scan of a persons torso, with brighter colors indicating denser cell clusters. A bright spot on the heart indicates that inflammatory cells are clustered around a site that has lost blood supply, causing a heart attack. An international team of researchers, including scientists at Washington University School of Medicine in St Continue reading →

Introduction For more than twenty years, heart failure (HF) has been recognized as a pandemic1 and up-to-date, evidence-based management guidelines have been established. In addition, the importance of early detection and the need for prevention strategies are also recognized. Continue reading →

Introduction Extracellular vesicles (EVs) including exosomes, microvesicles, and apoptotic bodies are produced and released by almost all types of cell. EVs vary in size, properties, and secretion pathway depending on the originating cell.1,2 Exosomes are small EVs (sEVs) which are formed by a process of inward budding in early endosomes to form multivesicular bodies (MVBs) with an average size of 100 nm, and released into the extracellular microenvironment to transfer their components.3,4 Microvesicles are composed of lipid components of the plasma membrane and their sizes range from 1001000 nm, whereas apoptotic bodies result from programmed cell death.5 Initially, EVs were considered to maintain cellular waste through release of unwanted proteins and biomolecules; later, these organelles were considered important for intercellular communications through various cargo molecules such as lipids, proteins, DNA, RNA, and microRNAs (miRNAs).6 Previously, it was suggested that EVs play a critical role in normal cells to maintain homeostasis and prevent cancer initiation. Inhibition of EVs secretion causes accumulation of nuclear DNA in the cytoplasm, leading to apoptosis.1 The induction of apoptosis is the principal event of the reactive oxygen species (ROS) dependent DNA damage response.7,8 Several studies reported that exosomes are synthesized by means of two major pathways, the endosomal sorting complexes required for transport (ESCRT)-dependent and ESCRT-independent, and the processes are highly regulated by multiple signal transduction cascades.18 Exosomes released from the cell through normal exocytosis mechanisms are characterized by vesicular docking and fusion with the aid of SNARE complexes. Continue reading →

Absorbable Heart Stent Market with Covid-19 Impact Analysis: Forecast to Show Spurring Growth by 2021-2027 to its research database. The global Absorbable Heart Stent Market research report is an output of a brief assessment and an extensive analysis of practical data collected from the global Absorbable Heart Stent Market. The data are collected on the basis of industrial drifts and demands related to the services & products. Continue reading →

Fort Collins, Colorado: Reports Globe added the latest research report on future growth opportunities, development trends, and forecasts for 2027 of the Absorbable Cardiac Stent Market. Continue reading →

ABSTRACT Background:Multiple myeloma is a plasma cell dyscrasia accounting for 1% of neoplastic diseases and is the second most common hematologic malignancy after lymphoma. Continue reading →