Category Archives: Myocardial Infarction

Abstract Objective To determine the association between levels of low density lipoprotein cholesterol (LDL-C) and all cause mortality, and the concentration of LDL-C associated with the lowest risk of all cause mortality in the general population. Design Prospective cohort study Continue reading →

This nationwide retrospective cohort study used the National Health Insurance Research Database of Taiwan to compare the impact of bleeding on clinical outcomes in patients with acute myocardial infarction (AMI) versus chronic coronary syndrome (CCS). Continue reading →

Living near hydraulic fracturing is associated with increased risk of hospitalization in people with heart failure (HF), a new study from Pennsylvania suggests. The link was strongest among those with more severe heart failure but patients with either HF phenotype showed this association of increased risk with exposure to fracking activities, according to the investigators, led by Tara P. McAlexander, PhD, MPH, Drexel University Dornsife School of Public Health in Philadelphia Continue reading →

The FDA has granted a Breakthrough Therapy designation to the KRAS G12C inhibitor sotorasib for the treatment of patients with locally advanced or metastatic nonsmall cell lung cancer (NSCLC) who harbored a KRAS G12C mutation as detected by an FDA-approved test and following at least 1 prior line of systemic therapy, announced Amgen, developer of the drug, in a press release. "Breakthrough Therapy designation and Real-Time Oncology Review bring Amgen closer to potentially providing a targeted therapy to patients with aKRAS G12Cmutation and establishing sotorasib as the foundational therapy inKRAS G12C-driven cancers," saidDavid M Continue reading →

This article was originally published here J Am Heart Assoc. 2020 Dec 7:e017729. doi: 10.1161/JAHA.120.017729 Continue reading →

After a first severe heart attack, women face a 20% increased risk of developing heart failure or dying within five years when compared with men, according to new findings. A fresh look at patient care may be warranted, investigators say. Continue reading →

This article was originally published here J Thromb Thrombolysis. 2020 Nov 30. Continue reading →

This article was originally published here Turk Kardiyol Dern Ars. Continue reading →

A new study suggests that COVID-19 guidance in Sweden may have reduced peoples risks of having a heart attack. By usinganonymouslocation data from mobilephones, researchers - which included Professor Chris Gale, Co-Director at the Leeds Institute for Data Analytics - developed an aggregate picture of the activities ofthe Swedish populationand mappeditagainstattendances at Sweden's 29emergencycardiac angiography units. Cardiac angiographyisusedto treat blockagesto thehearts bloodvessels that cause a heart attack Continue reading →

PLoS Med. 2020 Dec 4;17(12):e1003410. Continue reading →