Causes of Death in Patients with Acute and Chronic Myocardial Injury – DocWire News

BACKGROUND:

Information about causes of death in patients withmyocardialinjury is limited. The purpose of this study was to explore causes of death in patients withmyocardialinjury.

In a cohort of 22,589 patients, 3,853 patients withmyocardialinjury were identified and categorized into: type 1myocardial infarction, type 2myocardial infarction, and non-ischemic acute and chronicmyocardialinjury. We included all 1,466/3,853 (38%) patients who died during follow-up (3.9 2 years). We estimated rates and adjusted OR with 95% CI for causes of death in the four categories ofmyocardialinjury using patients withoutmyocardialinjury 819/17,932 (4.6%) who died as reference.

The study cohort included 2,285 patients. The proportion of cardiovascular deaths was higher in patients with type 1myocardial infarction(48%), acute (43%), and chronic (45%)myocardialinjury and type 2myocardial infarction(39%) compared with patients withoutmyocardialinjury (25%). Adjusted rates for cardiovascular death were similar in patients withmyocardialinjury. Type 1myocardial infarction, acute, and chronicmyocardialinjury was associated with a 77% (OR: 1.77, 95% CI 1.29-2.41), 40% (OR: 1.40, 95% CI: 1.07-1.84), and 36% (OR: 1.36, 95% CI: 1.05-1.76) higher risk of cardiovascular death.

Patients with type 1myocardial infarctionand acute or chronicmyocardialinjury have similar proportions and high risks for cardiovascular death. We believe that these findings stress the need for investigating patients without known heart diseases who present with non-ischemicmyocardialinjury, or type 2myocardial infarction.

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Causes of Death in Patients with Acute and Chronic Myocardial Injury - DocWire News