PURPOSE: Following a favourable pilot trial using a single-bolus of ciclosporin, it has been unclear why two large studies (CYCLE and CIRCUS) failed to prevent reperfusion injury and reduce infarct size in STEMI (ST elevationmyocardial infarction). The purpose of this study was to assess the effect of ciclosporin onmyocardialinjury, LV-remodelling, and lymphocyte kinetics in patients with acute STEMI undergoing primary PCI. Continue reading →

Heart disease is the primary cause of death worldwide, principally because the heart has minimal ability to regenerate muscle tissue. Myocardial infarction (heart attack) caused by coronary artery disease leads to heart muscle loss and replacement with scar tissue, and the heart's pumping ability is permanently reduced. Continue reading →

Over the 13-year period ending in 2016, revascularization procedural volumes have dropped by half, although the percentage of percutaneous coronary intervention (PCI) procedures done for myocardial infarction (MI) have more than doubled, a new administrative study shows. During the same period, risk-adjusted in-hospital mortality rates after coronary artery bypass grafting (CABG) have also improved, whereas in PCI for ST-segment elevation myocardial infarction (STEMI), they've hovered stubbornly around 5%. Continue reading →

HS:I have a deep-seated feeling within my core that how one takes care of a human is not proprietary. We should share that information. Continue reading →

Background Coexistence of cancer and cardiovascular disease is increasingly frequent, but nationwide data covering cancer patients withmyocardial infarction(MI) are scarce. Continue reading →