Scientists have developed a molecule that promotes the clearance of toxic clumps of the alpha-synuclein protein a hallmark of Parkinsons disease by targeting its template rather that the protein itself. We have found that targeting the RNA needed to build the toxic protein may be an optimal strategy to slowing or even stopping disease progression, Matthew Disney, PhD, chair of the chemistry department at the University of Floridas Institute for Biomedical Innovation & Technology and the studys lead author, said in a university social media release. The study, Decreasing the intrinsically disordered protein -synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera, was published in the journal PNAS. Continue reading →

We all know that there is no cure for Parkinsons disease but there exist natural treatments. It can ease the discomfort and help manage the symptoms in the long term. Continue reading →

A revolutionary solution to Parkinsons Freezing of Gait Freezing of gait (FoG) is a common, disabling symptom of Parkinsons disease, severely affecting a patients ability to walk and participate in daily activities. However, a revolutionary development in the field offers new hope. A wearable, soft, robotic device has been created to help individuals with Parkinsons disease overcome FoG Continue reading →

Coya Therapeutics is expanding the pipeline for its COYA 302 immunotherapy, adding two neurodegenerative disorders frontotemporal dementia (FTD) and Parkinsons disease as targets for the amyotrophic lateral sclerosis (ALS) treatment candidate. Brain inflammation is known to drive Parkinsons and is a mechanism shared across several neurodegenerative diseases. Continue reading →

When I was diagnosed with Parkinsons disease, one of my fears was that I would have to stop refereeing basketball. Continue reading →

Despite immense gains in knowledge about the disease in recent years, scientists still do not know what causes it and have struggled to find a treatment that will stop its progression once and for all. But now a potential new drug being tested by a group of Chinese scientists and clinicians may offer a glimmer of hope, with promising results after it was used on a severely affected patient for six months. Continue reading →