Adel Galeshi,1,2 Maryam Ghasemi-Kasman,3,4 Farideh Feizi,2,3 Nahid Davoodian,5,6 Leila Zare,7 Zeinab Abedian3 1Babol University of Medical Sciences, Babol, Iran; 2Department of Anatomical Sciences, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran; 3Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran; 4Neuroscience Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran; 5Molecular Medicine Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran; 6Department of Clinical Biochemistry, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran; 7Department of Physiology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran Correspondence: Maryam Ghasemi-KasmanHealth Research Institute, Babol University of Medical Sciences, PO Box 4136747176, Babol, IranTel +98 113 219 0557Fax +98 113 219 0557Email m.ghasemi@mubabol.ac.ir Farideh FeiziDepartment of Anatomical Sciences, Faculty of Medicine, Babol University of Medical Sciences, PO Box 4136747176, Babol, IranTel +98 113 219 2033Fax +98 113 219 9936Email faridehfeizi@yahoo.com Introduction: Based on beneficial effects of aspirin and mesenchymal stem cells (MSCs) on myelin repair, in a preset study, effects of co-administration of aspirin and conditioned medium from adipose tissue-derived stem cells (ADSC-CM) on functional recovery of optic pathway, demyelination levels, and astrocytes activation were evaluated in a lysolecithin (LPC)-induced demyelination model of optic chiasm.Methods: LPC (1%, 2 L) was injected into the rat optic chiasm and animals underwent daily intraperitoneal (i.p.) injections of ADSCs-CM and oral gavage of aspirin at a dose of 25 mg/kg for 14 days post LPC injection. The conductivity of visual signals was assessed using visual evoked potential recordings (VEPs) before LPC injection and on days 7 and 14 post lesion. Continue reading →

Share this Article You are free to share this article under the Attribution 4.0 International license. The CRISPR gene editing technique may provide the means for lifelong correction of the genetic mutation responsible for Duchenne muscular dystrophy, a new study with mice shows. Duchenne muscular dystrophy (DMD), a rare but devastating genetic disorder, causes muscle loss and physical impairment. Continue reading →

16 September 2019 Google has announced a new Healthcare and Medicines policy whereby clinics offering 'unproven or experimental medical techniques' will not be allowed to advertise on the platform. The policy will covermost stem cell and gene therapies, and follows a recent campaign by the FDA to take action against clinics offering unapproved stem cell treatments (see BioNews 949 and 916), as well as reports of patients being harmed by unregulated treatments (see BioNews893). 'This new policy will prohibit ads selling treatments that have no established biomedical or scientific basis Continue reading →