When I started my working life in a pediatric intensive care unit, I could not possibly have imagined that, 30 years later, I would be living through a phenomenal scientific revolution in which we are using mRNA to give the instructions a cell uses to make proteins. Even as recently as 2003, when the human genome was cloned and we were all brimming with curiosity about what it meant for DNA-based therapies, I do not think we realized that mRNA therapeutics would prove so attractive. The beauty of mRNA therapy is that it acts locally and transiently. Continue reading
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