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Cardiac Regeneration – Victor Chang Cardiac Research Institute

Posted: Published on May 30th, 2018

1.Sugimoto K, Hui SP, Sheng DZ, Kikuchi K. Dissection of zebrafish shha function using site-specific targeting with a Cre-dependent genetic switch.eLIFE DOI: 10.7554/eLife.24635. 2. Sugimoto K, Hui SP, Sheng DZ, Gonzalez-Rajal A, Nakayama M, Kikuchi K. Zebrafish Foxp3a is required for the maintenance of immune tolerance.Developmental and Comparative Immunology 73:156-62 (2017). 3. Xiang M. S. W., Kikuchi K, Endogenous mechanisms of cardiac regeneration.International Review of Cell and Molecular Biology 326:67-131 (2016). 4.Karra K, Knecht A, Kikuchi K, Poss KD. Myocardial NF-B activation is essential for zebrafish heart regeneration.Proceedings of the National Academy of Sciences of USA 112:13255-13260 (2015). 5.Kikuchi K. Dedifferentiation, transdifferentiation, and proliferation: mechanisms underlying cardiac regeneration in zebrafish.Current Pathobiology Reports 3:81-88 (2015). 6.Kikuchi K. Advances in understanding the mechanism of zebrafish heart regeneration.Stem Cell Research 13:542-555 (2014). 7. Nachtrab G, Kikuchi K, Tornini VA, and Poss KD. Transcriptional components of anteroposterior positional information during zebrafish fin regeneration.Development. 140:3754-64 (2013) 8.Fang Y, Gupta V, Karra R, Holdway JE, Kikuchi K, Poss KD. Translational profiling of cardiomyocytes identifies an early Jak1/Stat3 injury response required for zebrafish heart regeneration.Proceedings of the National Academy of Sciences of USA 110:13416-21 (2013). 9. Guner-Ataman B, Paffett-Lugassy N, Adams MS, Nevis KR, Jahangiri L, Obregon … Continue reading →

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Cardiac rhythm abnormalities – symptoms and treatment …

Posted: Published on May 30th, 2018

In order to understand how cardiac rhythm abnormalities occur and how different treatments can be effective, it is firstly important to appreciate how the normal heart works. To put it very simply, the heart has only one function and that is to maintain a continuous and adequate flow of blood around the body. Blood is the vehicle for delivering oxygen and nutrition to all the vital organs. Some organs such as the brain are extremely sensitive to deprivation from oxygen and glucose. If there is a disruption to blood supply for more than a few minutes irreversible damage may occur. The heart is a simple muscular pump that contracts every few seconds. There arefour cardiac chambers andfour major heart valves. Blood flows from the top atrial chambers to the lower ventricular muscular pumping chamber. The heart valves ensure that blood travel in a single direction only. Like many mechanical pumps the heart is controlled by electrical circuitry. An inbuilt pacemaker (sino atrial node) initiates an impulse that sends a wave of electricity over the muscle to make it contract. The impulse is then passed onto a middle relay station (the AV node), this is normally the only thread of connection … Continue reading →

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Heart Rhythm Abnormalities (Arrhythmias) – NYP.org

Posted: Published on May 30th, 2018

More than six million Americans live with an abnormal (often rapid or irregular) heartbeat called an arrhythmia. NewYork-Presbyterian is a leader in the control of arrhythmias, offering the latest diagnostic techniques and treatments to patients of all ages. Our treatments restore proper heart function and enable you to live a better quality of life by reducing your symptoms. We offer a range of treatment options for arrhythmias, including medication, catheter ablation, implanted devices, and surgery. When you come to us for your care, you benefit from our exceptional expertise in this area. You'll have access to all the experts needed for your care, including cardiologists, heart surgeons, and other specialists with expertise in the care of people with irregular heartbeat. We use the latest electrophysiology tests, heart imaging techniques, and other exams to identify the cause and location of your arrhythmia with precision. This knowledge enables us to put together a customized plan of care designed just for you. We may correct your arrhythmia using medication or catheter ablation, in which we interrupt the path of the abnormal electrical impulses in your heart, curing your arrhythmia. NewYork-Presbyterian is home to one of the largest programs for the implantation of devices … Continue reading →

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Dermatitis – Symptoms and causes – Mayo Clinic

Posted: Published on May 30th, 2018

Overview Dermatitis is a general term that describes an inflammation of the skin. Dermatitis can have many causes and occurs in many forms. It usually involves an itchy rash on swollen, reddened skin. Skin affected by dermatitis may blister, ooze, develop a crust or flake off. Examples of dermatitis include atopic dermatitis (eczema), dandruff and rashes caused by contact with any of a number of substances, such as poison ivy, soaps and jewelry with nickel in it. Dermatitis is a common condition that's not contagious, but it can make you feel uncomfortable and self-conscious. A combination of self-care steps and medications can help you treat dermatitis. Dermatitis care at Mayo Clinic Each type of dermatitis may look a little different and tends to occur on different parts of your body. The most common types of dermatitis include: See your doctor if: A number of health conditions, allergies, genetic factors and irritants can cause different types of dermatitis: A number of factors can increase your risk of developing certain types of dermatitis. Examples include: Scratching the itchy rash associated with dermatitis can cause open sores, which may become infected. These skin infections can spread and may very rarely become life-threatening. Avoiding … Continue reading →

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Hyperbaric Medicine – Lourdes Health System

Posted: Published on May 30th, 2018

Most people have heard of scuba divers entering hyperbaric chambers for emergency treatment of decompression sickness, also known as the bends. Lately, some athletes have also used the sealed chambers, claiming that breathing pure oxygen at high pressures for extended periods can heal sports injuries and improve musculoskeletal recovery. A patient undergoes hyperbaric oxygen treatment at the Center for Advanced Wound Healing and Hyperbaric Medicine at Our Lady of Lourdes Medical Center, Camden. But for each of those uses, many other individuals and patients have availed themselves of this type of therapy, known as HBOT or hyperbaric oxygen therapy, for more common medical conditions and a growing list of such conditions, at that. HBOT for wound healing, for example, has become an important treatment in wound care and is the most prominent and common application of this expanding form of therapy. The branch of medicine that provides this HBOT for wounds and many other applications is called Hyperbaric Medicine. Lourdes Health System is pleased to offer hyperbaric medicine services at both of our hospital locations, at Our Lady of Lourdes Medical Center and at Lourdes Medical Center of Burlington County. Together, Lourdes is helping to lead the region in making … Continue reading →

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Cardiac Nursing – 9781416029342 | US Elsevier Health Bookshop

Posted: Published on May 28th, 2018

Part I: Foundations of Cardiac Care 1.Cardiac Nursing Today: Evidence-Based Practice 2.Epidemiology of Coronary Artery Disease 3.Epidemiology of Heart Failure 4.Anatomy of the Cardiovascular System 5.Cardiovascular Physiology: The Myocardium 6.Adaptations to and During Exercise 7.Regulation of Blood Pressure and Cardiac Output 8.Systemic and Pulmonary Circulation 9.Inflammation 10.Pathogenesis of Atherosclerosis 11.Central and Autonomic Nervous System and the Heart 12.Nutrition 13.Genetic and Environmental Basis of Cardiac Disease 14.Impact of Aging on Cardiac Function 15.Impact of Cardiac Disease on Psychological State 16.Impact of Cardiac Disease on the Family 17.Sleep, Sleep Disorders, and Cardiac Disease 18.Impact of Cardiac Disease on Sexuality Part II: Core Competencies of Clinicians Practicing Across the Continuum of Care 19.Multidisciplinary Versus Interdisciplinary Care 20.Nurses in the Emergency Department 21.Nurses in Intensive Care 22.Nurses in Telemetry and Step-Down 23.Perioperative Nursing Care 24.Nurses in Outpatient Clinics 25.Cardiac Rehabilitation 26.Nurses in Home Care 27.Nurses in Hospice and Palliative Care 28.Nurses in the Cardiac Catheterization Laboratory 29.Nurse's Role in Exercise Testing and Noninvasive Imaging 30.Contributions of Clinical Pharmacologists 31.Contribution of Clinical Psychologists Part III: Risk Factor Modification in Primary, Secondary, and Tertiary Prevention 32.Primary Prevention in Childhood 33.Smoking 34.Dyslipidemia 35.Hypertension 36.Obesity 37.Metabolic Syndrome and Diabetes 38.Sedentary Lifestyle 39.Stress 40.Impact of Depression on Cardiac Disease … Continue reading →

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Cardiomyopathy what it is and types British Heart …

Posted: Published on May 28th, 2018

Types of cardiomyopathy There are three main types of inherited cardiomyopathy: Another type of cardiomyopathy, Takotsubo cardiomyopathy, can be caused by extreme stress. This type is not passed on through families and often disappears in time. Other, specialised types of cardiomyopathy include: You can find more information about these conditions on Cardiomyopathy UKs website. The changes to yourheartare different for each type of cardiomyopathy and can affect people differently. They all affect the structure of your heart and reduce its ability to pump blood around the body. They can also affect the way the electrical system makes your heart beat. You can read more about how each type of cardiomyopathy affects you and your heart on the pages listed on the right. Watch Deb's story on living with dilated cardiomyopathy. Although inherited cardiomyopathy cannot be cured, in most cases living with it will not affect your quality or length of life. There are many effective treatments that can help you control your symptoms such as: Your GP or cardiologist will be able to let you know what treatments are right for you. You may also need to make some lifestyle changes such as cutting down on the amount of alcohol … Continue reading →

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C3, C4, & C5 Vertebrae Spinal Cord Injury | SpinalCord.com

Posted: Published on May 28th, 2018

The C3, C4, and C5 vertebrae form the midsection of the cervical spine, near the base of the neck. Injuries to the nerves and tissue relating to the cervical regionare the most severe of all spinal cord injuries because the higher up in the spine an injury occurs, the more damage that is caused to the central nervous system. Depending on the how severe the damage to the spinal cord is, the injury may be noted as complete or incomplete. The C2 - C3 junction of the spinal column is important, as this is where flexion and extension occur (flexion is the movement of the chin toward the chest and extension is the backward movement of the head). Patients with spinal cord damage at the C3 level will have limited mobility in both their flexion and extension. Symptoms of a spinal cord injury corresponding toC3 vertebrae include: The portion of the spinal cord which relatesto the C4 vertebra directly affects the diaphragm. Patients with C4 spinal cord injuries typically need 24 hour-a-day support to breathe and maintain oxygen levels. Symptoms of a spinal cord injury corresponding toC4 vertebrae include: Damage to the spinal cord at the C5 vertebra affects the … Continue reading →

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Clinical Cardiology Section | Cleveland Clinic

Posted: Published on May 27th, 2018

Overview The Section of Clinical Cardiology is often times the area where patients first have access to specialized inpatient and outpatient heart care and long-term management of their conditions. We offer the latest innovations in cardiac care and clinical therapies to patients of all ages. We provide state-of-the-art tests and procedures to help make an accurate diagnosis and create a treatment plan. We see patients with very common heart problems, such as angina, artery problems, valvular heart disease, and heart failure. We also treat patients with some very rare forms of heart disease, including those who have been told by other doctors that their condition cannot be treated. Our cardiologists use a broad range of treatment options to give each patient the best care possible. These include lifestyle modification recommendations, medications and procedures. Our cardiologists also work closely with our team of cardiovascular surgeons, should surgery be the best treatment option. Our cardiologists treat all kinds of heart and blood vessel diseases including: The Section of Clinical Cardiology's primary mission is to deliver high quality, cardiovascular care to all of our patients, in the hospital as well as in the outpatient setting by: Treatment options include: Why choose Cleveland Clinic … Continue reading →

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Interventional radiology – Wikipedia

Posted: Published on May 27th, 2018

Interventional radiology Balloon dilatation of the stenosed internal jugular vein (photo from an X-ray angiograph monitor). While pressure in the balloon is relatively low, stenosis prevents the balloon from inflating in the middle. Further increase in pressure will dilate the narrowing and restore the full blood flow. Interventional radiology (IR), sometimes known as vascular and interventional radiology (VIR), is a medical specialty which provides minimally invasive image-guided diagnosis and treatment of disease. Although the range of procedures performed by interventional radiologists is broad, the unifying concept behind these procedures is the application of image guidance and minimally invasive techniques in order to minimize risk to the patient. Training for interventional radiology occurs in the residency portion of medical education, and has gone through developments. In 2000, the Society of Interventional Radiology (SIR) created a program named "Clinical Pathway in IR", which modified the "Holman Pathway" that was already accepted by the American Board of Radiology to including training in IR; this was accepted by ABR but was not widely adopted. In 2005 SIR proposed and ABR accepted another pathway called "DIRECT (Diagnostic and Interventional Radiology Enhanced Clinical Training) Pathway" to help trainees coming from other specialities learn IR; this too … Continue reading →

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