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Heart Disease – A Closer Look at Stem Cell Treatments

Posted: Published on May 27th, 2018

Cardiovascular disease is the number one cause of death worldwide in men, women and children, claiming more than 17 million lives each year. The effects of congestive heart failure and acute myocardial infarction (heart attack) present great challenges for doctors and researchers alike. In this section: Heart attacks cause damage to the heart muscle, making it less efficient at pumping blood throughout the circulatory system. Your heart is constructed of several types of cells. For mending damaged heart tissue, researchers generally focus on three specific heart cell types: Gladstone Institutes. Close up of a mouse heart stained to reveal the important structural protein that helps heart muscle cells to contract (red). The cell nuclei are labeled in magenta. Despite major advances in how heart disease is managed, heart disease is progressive. Once heart cells are damaged, they cannot be replaced efficiently, at least not as we understand the heart today. There is evidence that the heart has some repair capability, but that ability is limited and not yet well understood. Heart failure is a general term to describe a condition in which the hearts blood-pumping action is weaker than normal. How much weaker varies widely from person to person, but … Continue reading →

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ECU Interventional Cardiology Fellowship

Posted: Published on May 26th, 2018

The Department of Cardiovascular Sciences at East Carolina University offers a 12 month ACGME accredited fellowship program in Interventional Cardiology for those physicians who have completed a 3 year internal medicine residency and a 3 year cardiology fellowship. Our program provides training in all aspects of interventional cardiology including ICE, IVUS and Flow wire evaluations; PCI (including post IV lysis for STEMI); Angiojet and other aspiration thrombectomy modalities; Rotablator; Peripheral vascular interventions (including occasional venous PTA/stent, 4-vessel cerebral arteriography); Endomyocardial biopsies; Transseptal puncture; Complex PFO and ASD closure; Balloon valvuloplasty for AV or MV stenosis; VSD closure; Alcohol septal ablation for HOCM; and coronary aneurysm coiling. Our average interventional volume is 750 coronary interventions per year of which, 300 are performed via radial approach. We have three interventional faculty members with full time academic appointments who are dedicated to teaching. Research opportunities are plentiful including collaborative work with basic scientists. The Interventional Cardiology Fellowship at East Carolina University is an exciting place to learn and grow. Thank you for your interest in East Carolina University. If you have any further questions or need assistance, please contact echifellows@ecu.edu. View post: ECU Interventional Cardiology Fellowship … Continue reading →

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Cardiac regeneration: current therapiesfuture concepts …

Posted: Published on May 26th, 2018

Introduction In 2009 cardiovascular disease (CVD) still accounted for 32.3% of all deaths in the United States and therefore continues to be one of the main causes of death (1). From 1999 to 2009, the rate of death due to CVD has declined, but nevertheless the burden of disease remains high. Although improved medical care and acute management of myocardial infarction have led to a considerable reduction of early mortality rate survivors are susceptible to an increased prevalence of chronic heart failure as they develop scarring followed by ventricular remodeling despite optimum medical care (2,3). Interestingly, cardiovascular operations and interventional procedures increased by 28% from 2000 to 2010 implicating an enormous cost factor for the healthcare system (1). For 2009, it was estimated that the direct and indirect costs of CVD and stroke add up to about $312.6 billion in the United States, which was more than for any other diagnostic group (1). The main issue of current pharmacological, interventional or operative therapies is their disability to compensate the irreversible loss of functional cardiomyocytes (4). Hence, the future challenge of cardiovascular therapies will be the functional regeneration of myocardial contractility by novel concepts, like cell based therapy, tissue engineering or … Continue reading →

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2019 Vascular Cell Biology Conference GRC

Posted: Published on May 26th, 2018

The Vascular Cell Biology Gordon Research Conference is focused on integrative aspects of vascular biology and pathology. The main goal of the Conference is to discuss the emerging biological and translational concepts in the field, to provide an opportunity to learn about the most recent data and new experimental approaches. The conference will address the basic biology of vascular cells and the reciprocal connections between vasculature and human diseases ranging from cardiovascular, neurovascular and metabolic diseases to organ fibrosis and cancer. The program includes sessions focused on fundamental aspects of vascular biology, e.g. mechanisms of vascular specification and development, vascular cell differentiation, inflammation, vascular metabolism and mechanobiology of vascular and lymphatic systems. These will be combined with discussions of newer areas of vascular biology, e.g. regulation of vascular cell fate and its role in disease, advances in endothelial targeting, novel regulatory networks in vascular inflammation and aging. In parallel with human studies, various experimental models ranging from zebrafish to mouse will be discussed. The program includes a new afternoon session on career development, inclusion of women and minorities, discussion of specific opportunities for junior investigators in academia and industry, and international visibility of the next generation of vascular biologists. Every … Continue reading →

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PET/CT – Molecular Imaging – Nuclear MedicinePET-CTPET …

Posted: Published on May 26th, 2018

TRUE DISCOVERY AWAITS It takes a certain mind to go in search of true discovery. In PET/CT, they are the clinical researchers looking to set new standards of care and the practitioners working to deliver better outcomes for the patients they see every day. They are also the healthcare providers in developing regions looking to invest in their first molecular imaging technology. These are the minds that we collaborate with to come up with meaningful advancements in PET/CT technology. The promise of PET/CT is its ability to provide personalized care. Its high resolution and sensitivity allow it to detect small lesions and quantitative tools make it possible to more accurately monitor cancer therapy. It also has the potential to go beyond oncology with disease-specific tracers for neurology and cardiology. Our goal is to help deliver on the promise of personalized care and to make it accessible to as many people as possible. Accomplishing this goal requires a commitment to innovations that reduce dose and improve quantitation accuracy. It also means taking a comprehensive approach to PET/CT. By providing a complete technology solution from tracer development to systems, we can drive down costs and make it more accessible. It is also … Continue reading →

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Spinal Cord Injury Presentation and Treatment | Bone and Spine

Posted: Published on May 25th, 2018

Spinal cord injury is term used for spectrum of insults to the spinal cord which results in either temporary or permanent loss of function of the affected area of the cord. Spinal cord works to relay motor and sensory signals to the peripheral organs. Therefore the function affected are sensation, proprioreception, activity of smooth and striated muscles. The profile of the injury and region affected would determine the functions affected. This motor and sensory loss pattern in fact guides the clinicians to reach at the diagnosis of the levels of injury. At any level, the injury to spinal cord could be complete[ a total loss of sensation and muscle function at and below the level of injury] incomplete [sparing of some functions distal to level of injury indicating the signal transmission] The prognosis of the spinal cord injury depends on the severity of the injury and may range from complete recovery to permanent quadriplegia [cervical injuries] and complete paraplegia in lower injuries. Physical trauma like motor vehicle injury, gunshots, falls, or sports injuries are most common causes of injury to spinal cord. But the cord injury can also occur due to non-traumatic causes like infection, insufficient blood flow, and tumors. … Continue reading →

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Hormone Replacement Therapy | Hormonal Imbalance Treatment

Posted: Published on May 23rd, 2018

Palm Springs Life Extension Institute is the only clinic in the country that owns a U.S. Patent for growth hormone and other bio-identical hormone replacements. It is the only clinic that offers a cash reward of $25,000 to the public for non-patients who can show a difference of greater than 27 years between the persons biological age and calendar age. Many of its patients, including the founder, Dr. Edmund Chein, M.D. have accomplished this miraculous feat. As the only clinic in the U.S. that specializes in Longevity Medicine, the cliniccures menopause, andropause, atherosclerosis, elevated cholesterol, and hypertension without drugs or pharmaceuticals. It cures these diseases with bio-identical hormones and nutrition. It treats the cause of the disease and cures it rather than controlling the disease with pharmaceuticals. It is the use of bio-identical hormones and nutrition to cure and eliminate age related diseases such as hypertension, cholesterol elevation, osteoporosis, menopause, andropause, erectile dysfunction, atherosclerosis, dementia and Alzheimers disease. Hormones are emails, faxes and letters between organs in the body. Bio-identical hormone replacement therapy, including the use of Growth Hormone, is safe because the doctors simply replace the levels to the levels you had them when you were in your 20s. … Continue reading →

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Facts on Parkinson’s Disease Treatment – Is it Possible to …

Posted: Published on May 23rd, 2018

Research Fact 1*: "A clinical comparison of Mucuna pruriens (available in our kit) and synthetic Levodopa- a conventional drug used to treat Parkinson's, showed Mucuna exhibiting significantly better anti-parkinsonian effects and behavioural benefits with no side effects in the patients." 1 *Individual results may vary from individual to individual, as is seen in all clinical trials. Despite this peer reviewed scientific research these herbs and homeopathies may or may not have been approved by the FDA in every single country as a treatment or cure for Parkinsons disease yet. Hence one is advised to see a Doctor licensed in their city and state and we may only advertise our product in such countries for Brain and Nerve Health presently. Generally Ayurveda is only accepted as medicine in India. Homeopathy is considered medicine in most parts of the world but can only be used for over the counter issues in USA. Imagine getting back the life you once had. Do you remember how free it felt? If reclaiming that freedom is your aim, then please realize that it is essential for you to read this page and apply it to your life without delay, because nature alone completes you in many … Continue reading →

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Congenital Heart Defects, Simplified

Posted: Published on May 23rd, 2018

Good morning happy summer Lindsay and Ken Great news yesterday I passed my Peds Echo boards. Thank you both for the encouragement and very educational useful study tools! Sincerely Lanett Eddy, RDCS, AE,PE Ken Heidens Congenital Heart Defects, Simplified does for congenital heart disease what a map does for your road trip. Complex defects are laid out simply and logically, with well-executed artwork that makes this otherwise bewilderingly complicated field accessible, even to the non-expert. It is readable enough for any health professional to learn about this topic for the first time or to use as a refresher. It can also serve as a concise, crystal-clear bedside reference for the busy echocardiographer. William Davis, MD Author of Track Your Plaque: The only heart disease prevention program that shows how the new CT heart scans can be used to detect, track, and control coronary plaque Congenital Heart Defects, Simplified is destined to become the reference book for neonatal and pediatric units. The major defects are covered completely and succinctly in bullet format. The color illustrations help enormously in the understanding of each heart or vascular defect. These illustrations not only help clarify the issue for RNs, but they are also an … Continue reading →

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UKNEQAS for Molecular Genetics

Posted: Published on May 23rd, 2018

The United Kingdom National External Quality Assessment Services (UK NEQAS) for Molecular Genetics provides external quality assessment for a range of inherited diseases and acquired disorders currently tested in diagnostic molecularlaboratories. UK NEQAS for Molecular Genetics gives objective information and advice to clinical laboratories throughout laboratory molecular medicine on the quality of their analytical and interpretative performance, in order to help them provide accurate and reliable test results and advice to clinicians, which facilitates optimal patient care. Advances in our understanding of genetic diseases has led to a revolution in testing technologies. UK NEQAS for Molecular Genetics is committed to providing external quality assessment in this rapidly evolving field. The Scheme was granted unconditional accreditation by Clinical Pathology Accreditation in January 2001 until March 2016. The Scheme has been granted UK Accreditation Service (UKAS) accredititaion to ISO 17043 in March, 2016 and the scope can be accessed athttp://www.ukas.com/wp-content/uploads/schedule_uploads/00013/8505Proficiency%20Testing%20Multiple.pdf In addition to external quality assessment (EQA) for Molecular Genetics and Molecular Pathology, theEdinburgh centre also provides EQA for Peptidehormones, Tumourmarkers, Pregnancy testing and Maternal serum screening see http://edqas.org/ NHS Lothian operating UK NEQAS for Molecular Genetics.UK NEQAS for Molecular Genetics is a member of the United Kingdom National ExternalQuality Assessment Service … Continue reading →

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